Genetic and chemical inhibition of autophagy in zebrafish induced myeloproliferation

Autor: Yi Z, Chen X, Lau Jj, Alvin C.H. Ma, Hasan Kmm

Autophagy is an evolutionary conserved and dynamic lysosomal degradation process for cellular homeostasis and remodelling, which is essential for the development and maintenance of different hematopoietic fates. However, the roles of autophagy in def

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::95ad3308d536d8ffefa73ec9582b6b38
https://doi.org/10.1101/2021.06.14.448302

Metformin accelerates zebrafish heart regeneration by inducing autophagy.

Autor: Xie F; Department of Biomedical Sciences, City University of Hong Kong, Hong Kong, China., Xu S; School of Life Sciences, Guangxi Normal University, Guilin, China.; Guangxi Universities Key Laboratory of Stem Cell and Biopharmaceutical Technology, Guangxi Normal University, Guilin, China., Lu Y; Department of Biomedical Sciences, City University of Hong Kong, Hong Kong, China.; City University of Hong Kong Shenzhen Research Institute, Shenzhen, China., Wong KF; Department of Biomedical Engineering, The Hong Kong Polytechnic University, Hong Kong, China., Sun L; Department of Biomedical Engineering, The Hong Kong Polytechnic University, Hong Kong, China., Hasan KMM; Department of Health Technology and Informatics, The Hong Kong Polytechnic University, Hong Kong, China., Ma ACH; Department of Health Technology and Informatics, The Hong Kong Polytechnic University, Hong Kong, China., Tse G; Kent and Medway Medical School, Canterbury, UK., Manno SHC; Department of Biomedical Sciences, City University of Hong Kong, Hong Kong, China., Tian L; Department of Biomedical Sciences, City University of Hong Kong, Hong Kong, China., Yue J; Department of Biomedical Sciences, City University of Hong Kong, Hong Kong, China. jianbyue@cityu.edu.hk.; City University of Hong Kong Shenzhen Research Institute, Shenzhen, China. jianbyue@cityu.edu.hk., Cheng SH; Department of Biomedical Sciences, City University of Hong Kong, Hong Kong, China. bhcheng@cityu.edu.hk.

Publikováno v: NPJ Regenerative medicine [NPJ Regen Med] 2021 Oct 08; Vol. 6 (1), pp. 62. Date of Electronic Publication: 2021 Oct 08.

Monoallelic Mutations in CC2D1A Suggest a Novel Role in Human Heterotaxy and Ciliary Dysfunction.

Autor: Ma ACH; Department of Health Technology and Informatics, The Hong Kong Polytechnic University, Hong Kong Special Administrate Region, China (A.C.H., K.M.M.H.)., Mak CCY; Department of Paediatrics and Adolescent Medicine, Li Ka Shing Faculty of Medicine, The University of Kong Kong, Hong Kong Special Administrate Region, China (C.C.Y.M., K.S.Y., S.L.C.P., D.Y., M.H.C.Y., P.C.C., Y.F.C., B.H.Y.C.)., Yeung KS; Department of Paediatrics and Adolescent Medicine, Li Ka Shing Faculty of Medicine, The University of Kong Kong, Hong Kong Special Administrate Region, China (C.C.Y.M., K.S.Y., S.L.C.P., D.Y., M.H.C.Y., P.C.C., Y.F.C., B.H.Y.C.)., Pei SLC; Department of Paediatrics and Adolescent Medicine, Li Ka Shing Faculty of Medicine, The University of Kong Kong, Hong Kong Special Administrate Region, China (C.C.Y.M., K.S.Y., S.L.C.P., D.Y., M.H.C.Y., P.C.C., Y.F.C., B.H.Y.C.)., Ying D; Department of Paediatrics and Adolescent Medicine, Li Ka Shing Faculty of Medicine, The University of Kong Kong, Hong Kong Special Administrate Region, China (C.C.Y.M., K.S.Y., S.L.C.P., D.Y., M.H.C.Y., P.C.C., Y.F.C., B.H.Y.C.)., Yu MHC; Department of Paediatrics and Adolescent Medicine, Li Ka Shing Faculty of Medicine, The University of Kong Kong, Hong Kong Special Administrate Region, China (C.C.Y.M., K.S.Y., S.L.C.P., D.Y., M.H.C.Y., P.C.C., Y.F.C., B.H.Y.C.)., Hasan KMM; Department of Health Technology and Informatics, The Hong Kong Polytechnic University, Hong Kong Special Administrate Region, China (A.C.H., K.M.M.H.)., Chen X; Laboratory of Neurodegenerative Diseases, School of Biomedical Sciences, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong Special Administrative Region, China (X.C.)., Chow PC; Department of Paediatrics and Adolescent Medicine, Li Ka Shing Faculty of Medicine, The University of Kong Kong, Hong Kong Special Administrate Region, China (C.C.Y.M., K.S.Y., S.L.C.P., D.Y., M.H.C.Y., P.C.C., Y.F.C., B.H.Y.C.)., Cheung YF; Department of Paediatrics and Adolescent Medicine, Li Ka Shing Faculty of Medicine, The University of Kong Kong, Hong Kong Special Administrate Region, China (C.C.Y.M., K.S.Y., S.L.C.P., D.Y., M.H.C.Y., P.C.C., Y.F.C., B.H.Y.C.)., Chung BHY; Department of Paediatrics and Adolescent Medicine, Li Ka Shing Faculty of Medicine, The University of Kong Kong, Hong Kong Special Administrate Region, China (C.C.Y.M., K.S.Y., S.L.C.P., D.Y., M.H.C.Y., P.C.C., Y.F.C., B.H.Y.C.).

Publikováno v: Circulation. Genomic and precision medicine [Circ Genom Precis Med] 2020 Dec; Vol. 13 (6), pp. e003000. Date of Electronic Publication: 2020 Nov 16.