Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Hasan Alsaid"'
Autor:
Saaussan Madi, Fang Xie, Kamyar Farhangi, Chih-Yang Hsu, Shih-Hsun Cheng, Tolulope Aweda, Bhasker Radaram, Stephanie Slania, Tammy Lambert, Mary Rambo, Tina Skedzielewski, Austin Cole, Valeriia Sherina, Shannon McKearnan, Hoang Tran, Hasan Alsaid, Minh Doan, Alan H. Stokes, Derek T. O’Hagan, Giulietta Maruggi, Sylvie Bertholet, Stéphane T. Temmerman, Russell Johnson, Beat M. Jucker
Publikováno v:
Frontiers in Immunology, Vol 13 (2023)
The goal of this study was to utilize a multimodal magnetic resonance imaging (MRI) and positron emission tomography (PET) imaging approach to assess the local innate immune response in skeletal muscle and draining lymph node following vaccination in
Externí odkaz:
https://doaj.org/article/f8cb07fbb3844bfdbcb71445fb51ca9e
Autor:
Hasan Alsaid, Tinamarie Skedzielewski, Mary V Rambo, Kristen Hunsinger, Bao Hoang, William Fieles, Edward R Long, James Tunstead, Danielle J Vugts, Matthew Cleveland, Neil Clarke, Christopher Matheny, Beat M Jucker
Publikováno v:
PLoS ONE, Vol 12, Iss 4, p e0176075 (2017)
The purpose of this work was to use various molecular imaging techniques to non-invasively assess GSK2849330 (anti HER3 ADCC and CDC enhanced 'AccretaMab' monoclonal antibody) pharmacokinetics and pharmacodynamics in human xenograft tumor-bearing mic
Externí odkaz:
https://doaj.org/article/8a2ccc9895534f1ca10fbfa2c7a01728
Autor:
Weike Bao, Karpagam Aravindhan, Hasan Alsaid, Thimmaiah Chendrimada, Matthew Szapacs, David R Citerone, Mark R Harpel, Robert N Willette, John J Lepore, Beat M Jucker
Publikováno v:
PLoS ONE, Vol 6, Iss 8, p e23570 (2011)
BACKGROUND: The cardioprotective effects of glucagon-like peptide-1 (GLP-1) and analogs have been previously reported. We tested the hypothesis that albiglutide, a novel long half-life analog of GLP-1, may protect the heart against I/R injury by incr
Externí odkaz:
https://doaj.org/article/6d43856cf96b496c95295fae57d270ed
Autor:
Shih-Hsun Cheng, M. Reid Groseclose, Cindy Mininger, Mats Bergstrom, Lily Zhang, Stephen C. Lenhard, Tinamarie Skedzielewski, Zachary D. Kelley, Debra Comroe, Hyundae Hong, Haifeng Cui, Jennifer L. Hoover, Steve Rittenhouse, Stephen Castellino, Beat M. Jucker, Hasan Alsaid
Publikováno v:
Journal of Controlled Release. 352:199-210
Liposomes are promising targeted drug delivery systems with the potential to improve the efficacy and safety profile of certain classes of drugs. Though attractive, there are unique analytical challenges associated with the development of liposomal d
Autor:
Hasan Alsaid, Shih-Hsun Cheng, Meixia Bi, Fang Xie, Mary Rambo, Tinamarie Skedzielewski, Bao Hoang, Sunish Mohanan, Debra Comroe, Andrew Gehman, Chih-Yang Hsu, Kamyar Farhangi, Hoang Tran, Valeriia Sherina, Minh Doan, M. Reid Groseclose, Christopher B. Hopson, Sara Brett, Ian A. Wilson, Andrew Nicholls, Marc Ballas, Jeremy D. Waight, Beat M. Jucker
Publikováno v:
Molecular Imaging and Biology. 25:528-540
Purpose The presence and functional competence of intratumoral CD8+ T cells is often a barometer for successful immunotherapeutic responses in cancer. Despite this understanding and the extensive number of clinical-stage immunotherapies focused on po
Autor:
Howard M. Solomon, Stacia Murzyn, Joyce Rendemonti, Sharon Chapman, Shih‐Hsun Cheng, Beat M. Jucker, Dinesh Stanislaus, Andrew Gehman, Hasan Alsaid
Publikováno v:
Birth Defects Research.
Autor:
Rakesh Kumar, Jeffrey M. Axten, Beat M. Jucker, Hasan Alsaid, Anthony E. Choudhry, Nathan Gaul, Aaron Goetz, Brent Sanders, Thomas B. Stanley, Katherine Moss, David J. Figueroa, Shu-Yun Zhang, Elisabeth Minthorn, Qi Liu, Charity Atkins
Supplementary Material PDF file - 147K, Supplementary Methods: Immunohistochemistry and magnetic resonance imaging. Supplementary Table 1: Kinase selectivity profiling of GSK2656157. Supplementary Table 2: Gene list for Human UPR array
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1bae45c3c74dc63b99fc43eade9948d3
https://doi.org/10.1158/0008-5472.22399736
https://doi.org/10.1158/0008-5472.22399736
Autor:
Rakesh Kumar, Jeffrey M. Axten, Beat M. Jucker, Hasan Alsaid, Anthony E. Choudhry, Nathan Gaul, Aaron Goetz, Brent Sanders, Thomas B. Stanley, Katherine Moss, David J. Figueroa, Shu-Yun Zhang, Elisabeth Minthorn, Qi Liu, Charity Atkins
Supplementary Figures 1-3 PDF file - 245K, Supplementary Figure 1: Dose-dependent pharmacodynamic effect of GSK2656157 on PERK in mouse pancreas. Supplementary Figure 2: Specificity of phospho-PERK antibody in mouse cells. Supplementary Figure 3: Eff
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1be769ac9df05c7852876b0e255be076
https://doi.org/10.1158/0008-5472.22399739
https://doi.org/10.1158/0008-5472.22399739
Autor:
Tolulope A. Aweda, Shih-Hsun Cheng, Stephen C. Lenhard, Armin Sepp, Tinamarie Skedzielewski, Chih-Yang Hsu, Shelly Marshall, Heather Haag, Jonathan Kehler, Prabhas Jagdale, Alessia Peter, Michael A. Schmid, Andrew Gehman, Minh Doan, Andrew P. Mayer, Peter Gorycki, Marie Fanget, Christophe Colas, Brenda Smith, Curtis C. Maier, Hasan Alsaid
Publikováno v:
European journal of nuclear medicine and molecular imaging.
Purpose Sotrovimab (VIR-7831), a human IgG1κ monoclonal antibody (mAb), binds to a conserved epitope on the SARS-CoV-2 spike protein receptor binding domain (RBD). The Fc region of VIR-7831 contains an LS modification to promote neonatal Fc receptor
Autor:
Mark Reid Groseclose, Jeremy Barry, Yongle Pang, Jennifer Deutsch, Shannon Berry, Elaina McCormick, David K. Lim, Hoang Tran, Sean Maguire, Hasan Alsaid, Amine Aziez, Elaine Paul, Keyur Gada
Publikováno v:
Cancer Research. 83:3581-3581
Purpose: There remains an unmet need to provide effective treatment therapy for patients with primary and metastatic brain tumors; lack of drug penetration across the blood brain barrier (BBB) is a key factor. Synthetic lethality is an attractive mec