Human induced pluripotent stem cells display a similar mutation burden as embryonic pluripotent cells in vivo .

Autor: Hasaart KAL; Princess Máxima Center for Pediatric Oncology, Heidelberglaan 25, 3584 CS Utrecht, the Netherlands.; Oncode Institute, Jaarbeursplein 6, 3521 AL Utrecht, the Netherlands., Manders F; Princess Máxima Center for Pediatric Oncology, Heidelberglaan 25, 3584 CS Utrecht, the Netherlands.; Oncode Institute, Jaarbeursplein 6, 3521 AL Utrecht, the Netherlands., Ubels J; Princess Máxima Center for Pediatric Oncology, Heidelberglaan 25, 3584 CS Utrecht, the Netherlands.; Oncode Institute, Jaarbeursplein 6, 3521 AL Utrecht, the Netherlands., Verheul M; Princess Máxima Center for Pediatric Oncology, Heidelberglaan 25, 3584 CS Utrecht, the Netherlands.; Oncode Institute, Jaarbeursplein 6, 3521 AL Utrecht, the Netherlands., van Roosmalen MJ; Princess Máxima Center for Pediatric Oncology, Heidelberglaan 25, 3584 CS Utrecht, the Netherlands.; Oncode Institute, Jaarbeursplein 6, 3521 AL Utrecht, the Netherlands., Groenen NM; Princess Máxima Center for Pediatric Oncology, Heidelberglaan 25, 3584 CS Utrecht, the Netherlands.; Oncode Institute, Jaarbeursplein 6, 3521 AL Utrecht, the Netherlands., Oka R; Princess Máxima Center for Pediatric Oncology, Heidelberglaan 25, 3584 CS Utrecht, the Netherlands.; Oncode Institute, Jaarbeursplein 6, 3521 AL Utrecht, the Netherlands., Kuijk E; Oncode Institute, Jaarbeursplein 6, 3521 AL Utrecht, the Netherlands.; Center for Molecular Medicine, University Medical Center Utrecht, Universiteitsweg 100, 3584 CG Utrecht, the Netherlands., Lopes SMCS; Department of Anatomy and Embryology, Leiden University Medical Center, 2333 ZC Leiden, the Netherlands., Boxtel RV; Princess Máxima Center for Pediatric Oncology, Heidelberglaan 25, 3584 CS Utrecht, the Netherlands.; Oncode Institute, Jaarbeursplein 6, 3521 AL Utrecht, the Netherlands.

Publikováno v: IScience [iScience] 2022 Jan 06; Vol. 25 (2), pp. 103736. Date of Electronic Publication: 2022 Jan 06 (Print Publication: 2022).

Mutation accumulation and developmental lineages in normal and Down syndrome human fetal haematopoiesis.

Autor: Hasaart KAL; Princess Máxima Center for Pediatric Oncology and Oncode Institute, Heidelberglaan 25, 3584CS, Utrecht, The Netherlands., Manders F; Princess Máxima Center for Pediatric Oncology and Oncode Institute, Heidelberglaan 25, 3584CS, Utrecht, The Netherlands., van der Hoorn ML; Leiden University Medical Center, 2333 ZC, Leiden, The Netherlands., Verheul M; Princess Máxima Center for Pediatric Oncology and Oncode Institute, Heidelberglaan 25, 3584CS, Utrecht, The Netherlands., Poplonski T; Princess Máxima Center for Pediatric Oncology, Heidelberglaan 25, 3584CS, Utrecht, The Netherlands., Kuijk E; Center for Molecular Medicine, University Medical Center Utrecht and Oncode Institute, Universiteitsweg 100, 3584 CG, Utrecht, The Netherlands., de Sousa Lopes SMC; Department of Anatomy and Embryology, Leiden University Medical Center, 2333 ZC, Leiden, The Netherlands., van Boxtel R; Princess Máxima Center for Pediatric Oncology and Oncode Institute, Heidelberglaan 25, 3584CS, Utrecht, The Netherlands. R.vanBoxtel@prinsesmaximacentrum.nl.

Publikováno v: Scientific reports [Sci Rep] 2020 Jul 31; Vol. 10 (1), pp. 12991. Date of Electronic Publication: 2020 Jul 31.

Single-cell multi-omics map of human fetal blood in Down syndrome.

Autor: Marderstein, Andrew R., De Zuani, Marco, Moeller, Rebecca, Bezney, Jon, Padhi, Evin M., Wong, Shuo, Coorens, Tim H. H., Xie, Yilin, Xue, Haoliang, Montgomery, Stephen B., Cvejic, Ana

Publikováno v: Nature; Oct2024, Vol. 634 Issue 8032, p104-112, 9p