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Akademický článek

RCT-based Social Return on Investment (SROI) of a Home Exercise Program for People With Early Dementia Comparing In-Person and Blended Delivery Before and During the COVID-19 Pandemic

Autor: Kodchawan Doungsong MSc, Ned Hartfiel PhD, John Gladman MD, Rowan Harwood MD, Rhiannon Tudor Edwards DPhil

Publikováno v: Inquiry: The Journal of Health Care Organization, Provision, and Financing, Vol 61 (2024)

Regular exercise and community engagement may slow the rate of function loss for people with dementia. However, the evidence is uncertain regarding the cost-effectiveness and social return on investment (SROI) of home exercise with community referral

Externí odkaz: https://doaj.org/article/32c991041cda4d4180401faea8ccfc81

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Akademický článek

A diagnostic dilemma: Atypical melanocytic lesions arising in the setting of treatment with the BRAF inhibitor, vemurafenib

Autor: Mary Clark, MD, Paul Imbriano, DO, Michael Harwood, MD, Klaus Busam, MD, Leslie Robinson-Bostom, MD

Publikováno v: JAAD Case Reports, Vol 24, Iss , Pp 32-34 (2022)

Externí odkaz: https://doaj.org/article/4d0425d3b53948cb9b5d3bbc7ec6c4c5

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Akademický článek

Patient Resilience Has Moderate Correlation With Functional Outcomes, but Not Satisfaction, After Primary Unilateral Total Knee Arthroplasty

Autor: Amer Haffar, BS, Sean Bryan, MD, Marc Harwood, MD, Jess H. Lonner, MD

Publikováno v: Arthroplasty Today, Vol 10, Iss , Pp 123-127 (2021)

Background: As many as 20% of patients who undergo total knee arthroplasty (TKA) are dissatisfied. Psychological factors have been shown to play a role in outcomes after TKA. The purpose of this study was to investigate the impact of patient resilien

Externí odkaz: https://doaj.org/article/0cdb2f1a8ac44ec9afdd3c09f06bd408

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Akademický článek

Social Return on Investment of Home Exercise and Community Referral for People With Early Dementia

Autor: Ned Hartfiel PhD, John Gladman DM, Rowan Harwood MD, Rhiannon Tudor Edwards D.Phil

Publikováno v: Gerontology and Geriatric Medicine, Vol 8 (2022)

Exercise can improve physical function and slow the progression of dementia. However, uncertainty exists around the costeffectiveness of exercise programmes for people with early dementia. The aim of this study was to determine whether a home-based s

Externí odkaz: https://doaj.org/article/e3e87c75d4d449b0bce4ad0108755100

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Akademický článek

Catastrophic failure of an acetabular total hip arthroplasty component mimicking a posterior dislocation

Autor: Christopher Joyce, MD, Jared L. Harwood, MD, Andrew H. Glassman, MD, MS

Publikováno v: Arthroplasty Today, Vol 3, Iss 1, Pp 7-11 (2017)

In our case study, we examine a case of catastrophic failure of a total hip arthroplasty acetabular component leading to complete central wear by the ceramic femoral head, requiring revision total hip arthroplasty. Despite subtle clinical findings, i

Externí odkaz: https://doaj.org/article/9846d58fff54435cbe1311e37cd2bfb2

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Absolute abundance and function of intestinal drug transporters: a prerequisite for fully mechanistic in vitro–in vivo extrapolation of oral drug absorption

Autor: Harwood, MD, Neuhoff, S., Carlson, G.L., Warhurst, G., Rostami-Hodjegan, Amin

Publikováno v: Harwood, MD, Neuhoff, S, Carlson, G L, Warhurst, G & Rostami-Hodjegan, A 2013, ' Absolute abundance and function of intestinal drug transporters: a prerequisite for fully mechanistic in vitro–in vivo extrapolation of oral drug absorption ', Biopharm Drug Dispos, vol. 34, no. 1, pp. 2-28 . https://doi.org/10.1002/bdd.1810, https://doi.org/10.1002/bdd.1810

The use of whole body physiological-based pharmacokinetic (PBPK) models linked with in vitro-in vivo extrapolation (IVIVE) of kinetic parameters from laboratory experiments, has become embedded within many of the pharmaceutical industry and is used e

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::9a35f9d47fb6ce1bfc30cfcde3b43506
https://www.research.manchester.ac.uk/portal/en/publications/absolute-abundance-and-function-of-intestinal-drug-transporters-a-prerequisite-for-fully-mechanistic-in-vitroin-vivo-extrapolation-of-oral-drug-absorption(0c104604-3ce1-49b1-b704-59f8e1162e82).html

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