Zobrazeno 1 - 10
of 99
pro vyhledávání: '"Harvey W. Mohrenweiser"'
Autor:
Isaac Wirgin, Yelena Afanasyeva, Alan A. Arslan, Karen L. Koenig, Harvey W. Mohrenweiser, Paolo Toniolo, Roy E. Shore, Diane Currie, Anne Zeleniuch-Jacquotte
Publikováno v:
International Journal of Cancer. 122:2101-2105
To evaluate the associations of breast cancer risk with polymorphisms in the XPC and XPD/ERCC2 DNA nucleotide excision repair genes, a case-control study nested within a prospective cohort of 14,274 women was conducted. Genotypes were characterized f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da60c9fadf9e8c9c040d4a67e1558e60
https://doi.org/10.1002/ijc.23361
https://doi.org/10.1002/ijc.23361
Autor:
Harvey W. Mohrenweiser
Publikováno v:
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis. 616:221-226
Systematic screens have revealed extensive DNA sequence variation existing in the human population. Studies of the role of polymorphic genetic variants in explaining the association of family history with risk of common disease have generally focused
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::562328cea9df964904dc98bfe7fa9c53
https://doi.org/10.1016/j.mrfmmm.2006.11.008
https://doi.org/10.1016/j.mrfmmm.2006.11.008
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 314:923-931
The human organic anion transporter hOAT1 ( SLC22A6 ) contributes to the uptake of a range of small organic anions across the basolateral membrane of the renal proximal tubule and drives their urinary elimination. The aim of this study was to identif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee14c583f39c482020dc41eb8fe1f0fc
https://doi.org/10.1124/jpet.105.084301
https://doi.org/10.1124/jpet.105.084301
Publikováno v:
Genomics. 83:970-979
Over 520 different amino acid substitution variants have been previously identified in the systematic screening of 91 human DNA repair genes for sequence variation. Two algorithms were employed to predict the impact of these amino acid substitutions
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::178301df6eb3836bc3e895954dda21cf
https://doi.org/10.1016/j.ygeno.2003.12.016
https://doi.org/10.1016/j.ygeno.2003.12.016
Autor:
Joseph E. Maxwell, Beata D. Przybyla-Zawislak, Johana Vázquez-Matías, Harvey W. Mohrenweiser, Ahmed Enayetallah, Bruce D. Hammock, David F. Grant, Punit K. Srivastava, Darryl C. Zeldin, J. Alyce Bradbury
Publikováno v:
Molecular Pharmacology. 64:482-490
Human soluble epoxide hydrolase (hsEH) metabolizes a variety of epoxides to the corresponding vicinal diols. Arachidonic and linoleic acid epoxides are thought to be endogenous substrates for hsEH. Enzyme activity in humans shows high interindividual
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ddda8f4716ada0925324ad1cd8e3694
https://doi.org/10.1124/mol.64.2.482
https://doi.org/10.1124/mol.64.2.482
Autor:
Mark Steven Miller, Ethan M. Lange, L. Douglas Case, Kurt Lohman, Tasha R. Smith, Harvey W. Mohrenweiser, Jennifer J. Hu
Publikováno v:
Cancer Letters. 190:183-190
Mammalian cells are constantly exposed to a wide variety of genotoxic agents from both endogenous and exogenous sources. Genetic variability in DNA repair may contribute to human cancer risk. We used a case-control study design (162 cases and 302 con
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1c75ce9ce81f6b4690a38fa1177590c
https://doi.org/10.1016/s0304-3835(02)00595-5
https://doi.org/10.1016/s0304-3835(02)00595-5
Publikováno v:
Toxicology Letters. 120:269-280
Everyone has a unique combination of polymorphic traits that modify susceptibility and response to drugs, chemicals and carcinogenic exposures. The metabolism of exogenous and endogenous chemical toxins may be modified by inherited and induced variat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c51f7add6f9ad9ec839e5e44164d3f7
https://doi.org/10.1016/s0378-4274(01)00279-x
https://doi.org/10.1016/s0378-4274(01)00279-x
Autor:
Cheryl L. Soderberg, David N. Louis, Bernd W. Scheithauer, Justin S. Smith, Thomas J. Borell, Arie Perry, Robert B. Jenkins, Andreas von Deimling, Ute Pohl, Sandra M. Hosek, Harvey W. Mohrenweiser, Issei Tachibana, Hyun K. Lee, Junqi Qian
Publikováno v:
Genes, Chromosomes and Cancer. 29:16-25
Allelic loss of chromosome arm 19q is a frequent event in human diffuse glioma, suggesting the presence of a tumor suppressor gene. Previous loss of heterozygosity (LOH) analyses have mapped this gene to a 1.4-megabase interval, between the genetic m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2db43ddae0395774cfcf976577c92764
https://doi.org/10.1002/1098-2264(2000)9999:9999<::aid-gcc1007>3.3.co
https://doi.org/10.1002/1098-2264(2000)9999:9999<::aid-gcc1007>3.3.co
Autor:
Xiaobing Yu, Kun Shen, Harvey W. Mohrenweiser, Kyung Chin, Constance Tom Noguchi, Bojana B. Beleslin-Cokic, Chun Liu
Publikováno v:
Molecular Brain Research. 81:29-42
The expression of erythropoietin receptor (EpoR) in brain and neuronal cells, and hypoxia-responsive production of erythropoietin (Epo) in the brain suggests that the function of Epo as a survival or viability factor may extend beyond hematopoietic t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::765f7857a5179c34742336a951777d2a
https://doi.org/10.1016/s0169-328x(00)00157-1
https://doi.org/10.1016/s0169-328x(00)00157-1
Autor:
Ute Pohl, Harvey W. Mohrenweiser, Thomas J. Borell, Cheryl L. Soderberg, Junqi Qian, Hyun K. Lee, Andreas von Deimling, David N. Louis, Robert B. Jenkins, Arie Perry, Bernd W. Scheithauer, Justin S. Smith, Sandra M. Hosek, Issei Tachibana
Publikováno v:
Genes, Chromosomes and Cancer. 29:16-25
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b09b1d4ae23d94c0071734858bc91653
https://doi.org/10.1002/1098-2264(2000)9999:9999<::aid-gcc1007>3.0.co
https://doi.org/10.1002/1098-2264(2000)9999:9999<::aid-gcc1007>3.0.co