Zobrazeno 1 - 10
of 167
pro vyhledávání: '"Harvey R. Gralnick"'
Autor:
Longen Zhou, Sybil B. Williams, Rui G. Rodrigues, John M. Sipes, Harvey R. Gralnick, Neng-Hua Guo, David D. Roberts, Nancy Smyth Templeton
Publikováno v:
Journal of Biological Chemistry. 276:27913-27922
The recognition of extracellular matrix components can be regulated by conformational changes that alter the activity of cell surface integrins. We now demonstrate that conformational regulation of the matrix glycoprotein thrombospondin-1 (TSP1) can
Publikováno v:
Thrombosis Research. 92:195-198
intact platelet membrane glycoprotein Ib (GPIb), of platelet concentrates over a period of 6 days and which is a critical protein for binding of von Willebrand factor (vWf). The reduction in GPIb integ- have analyzed the correlation of these paramete
Autor:
Kristin Hansmann, McDonald K. Horne, Margaret E. Rick, Laurie P. McKeown, William A. Gahl, Kathryn E. Rosenfeld, Stephen J. Rosenfeld, Olga J. Wilson, Harvey R. Gralnick
Publikováno v:
American Journal of Hematology. 59:115-120
The Hermansky-Pudlak Syndrome (HPS) is an autosomal recessive inherited disorder characterized by oculocutaneous albinism, tissue accumulation of ceroid pigment, and a mild to moderate bleeding diathesis attributed to storage-pool deficient (SPD) pla
Autor:
Robert Yarchoan, Harvey R. Gralnick, Kathleen M. Wyvill, Tena Knudson, Perdita Taylor, Steven L. Zeichner, Sybil B. Williams, Masayuki Sano, McDonald K. Horne, Nikisha Smith
Publikováno v:
Journal of Laboratory and Clinical Medicine. 132:303-307
Glycocalicin (GC) is the carbohydrate-rich portion of platelet membrane glycoprotein Ib(alpha) that can be cleaved from circulating platelets by proteases. The plasma GC level is an indicator of platelet turnover. Using an ELISA for GC, we assayed th
Publikováno v:
Thrombosis Research. 86:417-421
Autor:
P. Merryman, Douglas L. Fraker, W. S. Arnold, McDonald K. Horne, S. H. Tannenbaum, Harvey R. Gralnick, Kelvin C. Yu, H R Alexander
Publikováno v:
Thrombosis and Haemostasis. 77:053-056
SummaryRegional limb perfusion with antineoplastic agents stresses the local vasculature in a variety of ways. However, by monitoring the perfusates from limbs treated with melphalan alone or with melphalan plus tumor necrosis factor (TNF) and interf
Publikováno v:
Journal of the American College of Cardiology. 28(7):1789-1795
ObjectivesMechanisms underlying the morning increase in platelet aggregation produced by arising and assuming the upright posture were studied by examining 1) the expression on the platelet surface of activation-dependent markers; 2) platelet aggrega
Autor:
Harvey R. Gralnick, Kathryn E. Goad
Publikováno v:
Hematology/Oncology Clinics of North America. 10:457-484
Coagulation disorders are common in cancer patients. This article reviews the coagulation laboratory findings in these patients and the thromboembolic and hemorrhagic manifestations of malignancy. Among the many topics addressed are Trousseau's syndr
Autor:
Kristin Hansmann, Harvey R. Gralnick, Paula K. Merryman, Laurie P. McKeown, Olga J. Wilson, G. Connaghan
Publikováno v:
American Journal of Hematology. 51:158-163
DDAVP is effective treatment in most types of von Willebrand's disease; however, in type 2B von Willebrand's disease the use of DDAVP has been contraindicated due to DDAVP-induced thrombocytopenia. Several reports have confirmed the thrombocytopenic
Autor:
Michael Vail, Harvey R. Gralnick, I. Chu, Paula K. Merryman, Laurie P. McKeown, Olga J. Wilson, Janice Kimball
Publikováno v:
British Journal of Haematology. 91:697-702
One of the major causes of morbidity and mortality in paroxysmal nocturnal haemoglobinuria (PNH) is venous thrombosis. We have studied fibrinolysis, coagulation and platelets in 11 patients with PNH in an attempt to identify the possible mechanism(s)