Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Harvey Perez"'
Publikováno v:
Endocrinology and Metabolism, Vol 39, Iss 2, Pp 191-205 (2024)
In the quest to combat insulin-dependent diabetes mellitus (IDDM), allogenic pancreatic islet cell therapy sourced from deceased donors represents a significant therapeutic advance. However, the applicability of this approach is hampered by donor sca
Externí odkaz:
https://doaj.org/article/b75f2fdb2d2c4dfaabbc7bed1b0d1c33
Autor:
Harvey Perez, May F Abdallah, Jose I Chavira, Angelina S Norris, Martin T Egeland, Karen L Vo, Callan L Buechsenschuetz, Valentina Sanghez, Jeannie L Kim, Molly Pind, Kotoka Nakamura, Geoffrey G Hicks, Richard A Gatti, Joaquin Madrenas, Michelina Iacovino, Peter J McKinnon, Paul J Mathews
Publikováno v:
eLife, Vol 10 (2021)
Ataxia Telangiectasia (A-T) and Ataxia with Ocular Apraxia Type 1 (AOA1) are devastating neurological disorders caused by null mutations in the genome stability genes, A-T mutated (ATM) and Aprataxin (APTX), respectively. Our mechanistic understandin
Externí odkaz:
https://doaj.org/article/58f72a12e1074e83ad3fff4ba229dc94
Autor:
Stefania Beretta, Kelly M. Cunningham, Daniel L. Haus, Eric M. Gold, Harvey Perez, Luci López-Velázquez, Brian J. Cummings
Publikováno v:
Cell Transplantation, Vol 26 (2017)
Traumatic brain injury (TBI) is one of the leading causes of death and disability in the population worldwide, with a broad spectrum of symptoms and disabilities. Posttraumatic hyperexcitability is one of the most common neurological disorders that a
Externí odkaz:
https://doaj.org/article/dda844fe5b544e0d94fae15628416cda
Autor:
Daniel L. Haus, Hal X. Nguyen, Eric M. Gold, Noriko Kamei, Harvey Perez, Harry D. Moore, Aileen J. Anderson, Brian J. Cummings
Publikováno v:
Stem Cell Research, Vol 13, Iss 2, Pp 214-226 (2014)
Common methods for the generation of human embryonic-derived neural stem cells (hNSCs) result in cells with potentially compromised safety profiles due to maintenance of cells in conditions containing non-human proteins (e.g. in bovine serum or on mo
Externí odkaz:
https://doaj.org/article/0afe92b0566e46269311a9bc172a542f
Autor:
Paul J. Mathews, Joaquín Madrenas, Molly Pind, Jose I Chavira, Karen L Vo, Richard A. Gatti, Callan L Buechsenschuetz, Peter J. McKinnon, Jeannie L Kim, Kotoka Nakamura, Angelina S Norris, May F Abdallah, Martin T. Egeland, Michelina Iacovino, Geoffrey G. Hicks, Harvey Perez, Valentina Sanghez
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f8d4c48beecfc326da3f1191f97d04c9
https://doi.org/10.7554/elife.64695.sa2
https://doi.org/10.7554/elife.64695.sa2
Autor:
Martin T. Egeland, Angelina S Norris, Molly Pind, Valentina Sanghez, Harvey Perez, Michelina Iacovino, Joaquín Madrenas, Karen L Vo, Peter J. McKinnon, Paul J. Mathews, Callan L Buechsenschuetz, Kotoka Nakamura, May F Abdallah, Geoffrey G. Hicks, Jose I Chavira, Richard A. Gatti, Jeannie L Kim
Publikováno v:
eLife, Vol 10 (2021)
eLife
eLife
Ataxia Telangiectasia (A-T) and Ataxia with Ocular Apraxia Type 1 (AOA1) are devastating neurological disorders caused by null mutations in the genome stability genes, A-T mutated (ATM) and Aprataxin (APTX), respectively. Our mechanistic understandin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3f67ace6e99390e76a16a7eed29d9f9
https://doi.org/10.1101/2020.11.23.394098
https://doi.org/10.1101/2020.11.23.394098
Autor:
Kelly M. Cunningham, Luci López-Velázquez, Daniel L. Haus, Eric M. Gold, Stefania Beretta, Harvey Perez, Brian J. Cummings
Publikováno v:
Beretta, S; Cunningham, KM; Haus, DL; Gold, EM; Perez, H; Lopez-Velazquez, L; et al.(2017). Effects of Human ES-Derived Neural Stem Cell Transplantation and Kindling in a Rat Model of Traumatic Brain Injury. CELL TRANSPLANTATION, 26(7), 1247-1261. doi: 10.1177/0963689717714107. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/16n2434w
Beretta, S; Cunningham, K; Haus, D; Gold, E; Perez, H; López-Velázquez, L; et al.(2016). Effects of Human ES-Derived Neural Stem Cell Transplantation and Kindling in a Rat Model of Traumatic Brain Injury.. Cell transplantation. doi: 10.3727/096368916x693815. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/2g88j187
Cell Transplantation, Vol 26 (2017)
Cell Transplantation
Beretta, S; Cunningham, K; Haus, D; Gold, E; Perez, H; López-Velázquez, L; et al.(2016). Effects of Human ES-Derived Neural Stem Cell Transplantation and Kindling in a Rat Model of Traumatic Brain Injury.. Cell transplantation. doi: 10.3727/096368916x693815. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/2g88j187
Cell Transplantation, Vol 26 (2017)
Cell Transplantation
Traumatic brain injury (TBI) is one of the leading causes of death and disability in the population worldwide, with a broad spectrum of symptoms and disabilities. Posttraumatic hyperexcitability is one of the most common neurological disorders that a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1252e75f4aa9d6463a549ab417c2edd2
http://www.escholarship.org/uc/item/16n2434w
http://www.escholarship.org/uc/item/16n2434w
Autor:
Aileen J. Anderson, Daniel L. Haus, Noriko Kamei, Eric M. Gold, Harry Moore, Brian J. Cummings, Hal X. Nguyen, Harvey Perez
Publikováno v:
Stem cell research
Stem Cell Research, Vol 13, Iss 2, Pp 214-226 (2014)
Stem cell research, vol 13, iss 2
Haus, DL; Nguyen, HX; Gold, EM; Kamei, N; Perez, H; Moore, HD; et al.(2014). CD133-enriched Xeno-Free human embryonic-derived neural stem cells expand rapidly in culture and do not form teratomas in immunodeficient mice. Stem Cell Research, 13(2), 214-226. doi: 10.1016/j.scr.2014.06.008. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/52h60563
Stem Cell Research, Vol 13, Iss 2, Pp 214-226 (2014)
Stem cell research, vol 13, iss 2
Haus, DL; Nguyen, HX; Gold, EM; Kamei, N; Perez, H; Moore, HD; et al.(2014). CD133-enriched Xeno-Free human embryonic-derived neural stem cells expand rapidly in culture and do not form teratomas in immunodeficient mice. Stem Cell Research, 13(2), 214-226. doi: 10.1016/j.scr.2014.06.008. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/52h60563
Common methods for the generation of human embryonic-derived neural stem cells (hNSCs) result in cells with potentially compromised safety profiles due to maintenance of cells in conditions containing non-human proteins (e.g. in bovine serum or on mo
Autor:
Luci López-Velázquez, George A Lacuesta, Diane Su, Daniel L. Haus, Harvey Perez, Brian J. Cummings, Eric M. Gold, Aileen J. Anderson
Publikováno v:
Regenerative Medicine. 8:483-516
Traumatic brain injury (TBI) ranks as the leading cause of mortality and disability in the young population worldwide. The annual US incidence of TBI in the general population is estimated at 1.7 million per year, with an estimated financial burden i
Autor:
Daniel L. Haus, Mitra J. Hooshmand, Harvey Perez, Christopher J. Sontag, Brian J. Cummings, Aileen J. Anderson
Publikováno v:
Regenerative Medicine. 6:367-406
There is potential for a variety of stem cell populations to mediate repair in the diseased or injured CNS; in some cases, this theoretical possibility has already transitioned to clinical safety testing. However, careful consideration of preclinical