Mapping the landscape of histomorphological cancer phenotypes using self-supervised learning on unannotated pathology slides

Autor: Adalberto Claudio Quiros, Nicolas Coudray, Anna Yeaton, Xinyu Yang, Bojing Liu, Hortense Le, Luis Chiriboga, Afreen Karimkhan, Navneet Narula, David A. Moore, Christopher Y. Park, Harvey Pass, Andre L. Moreira, John Le Quesne, Aristotelis Tsirigos, Ke Yuan

Publikováno v: Nature Communications, Vol 15, Iss 1, Pp 1-24 (2024)

Abstract Cancer diagnosis and management depend upon the extraction of complex information from microscopy images by pathologists, which requires time-consuming expert interpretation prone to human bias. Supervised deep learning approaches have prove

Externí odkaz: https://doaj.org/article/24019f1068da441492cffc896558e017

New or enlarging hiatal hernias after thoracic surgery for early lung cancerCentral MessagePerspective

Autor: Kimberly J. Song, MD, Rowena Yip, MPH, Michael Chung, MD, Qiang Cai, MD, PhD, Yeqing Zhu, MD, PhD, Ayushi Singh, MD, Erik E. Lewis, MD, David Yankelevitz, MD, Emanuela Taioli, MD, PhD, Claudia Henschke, MD, PhD, Raja Flores, MD, Andrew Kaufman, MD, Dong-Seok Lee, MD, Daniel Nicastri, MD, Andrea Wolf, MD, Kimberly Song, MD, Kenneth Rosenzweig, MD, Jorge Gomez, MD, Mary Beth Beasley, MD, Maureen Zakowski, MD, David F. Yankelevitz, MD, Claudia I. Henschke, PhD, MD, Rebecca Schwartz, MD, Huiwen Chan, Jeffrey Zhu, Sydney Kantor, Shana Adler, Wissam Raad, MD, Zrzu Buyuk, MD, Adie Friedman, MD, Ronald Dreifuss, MD, Stacey Verzosa, MD, Mariya Yakubox, NP, Karina Aloferdova, NP, Patricia Stacey, Simone De Nobrega, Ardeshir Hakami, MD, Harvey Pass, MD, Berne Crawford, MD, Jessica Donnington, MD, Benjamin Cooper, MD, Andre Moreirea, MD, Audrey Sorensen, RN, Leslie Kohman, MD, Robert Dunton, MD, Jason Wallen, MD, Christopher Curtiss, MD, Ernest Scalzetti, MD, Linda Ellinwood, RN, Clifford P. Connery, MD, Emilo Torres, MD, Dan Cruzer, MD, Bruce Gendron, MD, Sonya Alyea, NP, Daniel Lackaye, Lauren Studer, Claudia Henschke, PhD, MD, Rebecca Schwartz, PhD, Betsy Becker, PhD, Artit Jirapatnakul, PhD, Nan You, MS, Huiwen Chan, MPH, MBA, Claudia I. Henschke, David F. Yankelevitz, Rowena Yip, Artit Jirapatnakul, Raja Flores, Andrea Wolf, Daniel M. Libby, James P. Smith, Mark Pasmantier, A.P. Reeves, Steven Markowitz, Albert Miller, Jose Cervera Deval, Heidi Roberts, Demetris Patsios, Shusuke Sone, Takaomi Hanaoka, Javier Zulueta, Juan P. de-Torres, Maria D. Lozano, Ralph Aye, Kristin Manning, Christiana Care, Thomas Bauer, Stefano Canitano, Salvatore Giunta, Enser Cole, Karl Klingler, John H.M. Austin, Gregory D.N. Pearson, Dorith Shaham, Cheryl Aylesworth, Patrick Meyers, Shahriyour Andaz, Davood Vafai, David Naidich, Georgeann McGuinness, Barry Sheppard, Matthew Rifkin, M. Kristin Thorsen, Richard Hansen, Samuel Kopel, William Mayfield, Dan Luedke, Donald Klippenstein, Alan Litwin, Peter A. Loud, Leslie J. Kohman, Ernest M. Scalzetti, Richard Thurer, Nestor Villamizar, Arfa Khan, Rakesh Shah, Xueguo Liu, Gary Herzog, Diana Yeh, Ning Wu, Joseph Lowry, Mary Salvatore, Carmine Frumiento, David S. Mendelson, Michael V. Smith, Robert Korst, Jana Taylor, Michelle S. Ginsberg, Michaela Straznicka, Mark Widmann, Gary Cecchi, Terence A.S. Matalon, Paul Scheinberg, Shari-Lynn Odzer, David Olsen, Fred Grannis, Arnold Rotter, Daniel Ray, David Mullen, Peter H. Wiernik, Edson H. Cheung, Melissa Lim, Louis DeCunzo, Robert Glassberg, Harvey Pass, Carmen Endress, Mark Yoder, Palmi Shah, Laura Welch, Michael Kalafer, Jeremy Green, James Walsh, David Bertsch, Elmer Camacho, Cynthia Chin, James O'Brien, James C. Willey

Publikováno v: JTCVS Open, Vol 10, Iss , Pp 415-423 (2022)

Objective: The study objective was to determine the relationship between lung resection and the development of postoperative hiatal hernia. Methods: Preoperative and postoperative computed tomography imaging from 373 patients from the International E

Externí odkaz: https://doaj.org/article/4f65b79d99da4ce3a91fab0dfbad99db

Combined Radiomic and Visual Assessment for Improved Detection of Lung Adenocarcinoma Invasiveness on Computed Tomography Scans: A Multi-Institutional Study

Autor: Pranjal Vaidya, Kaustav Bera, Philip A. Linden, Amit Gupta, Prabhakar Shantha Rajiah, David R. Jones, Matthew Bott, Harvey Pass, Robert Gilkeson, Frank Jacono, Kevin Li-Chun Hsieh, Gong-Yau Lan, Vamsidhar Velcheti, Anant Madabhushi

Publikováno v: Frontiers in Oncology, Vol 12 (2022)

ObjectiveThe timing and nature of surgical intervention for semisolid abnormalities are dependent upon distinguishing between adenocarcinoma-in-situ (AIS), minimally invasive adenocarcinoma (MIA), and invasive adenocarcinoma (INV). We sought to devel

Externí odkaz: https://doaj.org/article/77835c2afa8c4062b51d5989a9369b9a

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