Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Harvey M. Morris"'
Autor:
Jonathan Savitz, Wayne C. Drevets, Teresa A. Victor, Robert Dantzer, Harvey M. Morris, Bart N. Ford, Brent E. Wurfel, T. Kent Teague, Timothy B. Meier, Jerzy Bodurka
Publikováno v:
Brain, Behavior, and Immunity. 53:39-48
Reductions in gray matter volume of the medial prefrontal cortex (mPFC), especially the rostral and subgenual anterior cingulate cortex (rACC, sgACC) are a widely reported finding in major depressive disorder (MDD). Inflammatory mediators, which are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69a0215769f57ead311626127105ebcd
https://doi.org/10.1016/j.bbi.2015.11.003
https://doi.org/10.1016/j.bbi.2015.11.003
Activation of the kynurenine pathway is associated with striatal volume in major depressive disorder
Autor:
Wayne C. Drevets, Timothy B. Meier, Jonathan Savitz, Teresa A. Victor, Brent E. Wurfel, T. Kent Teague, Harvey M. Morris, Bart N. Ford, Robert Dantzer, Scott A. McIntosh, Jerzy Bodurka
Publikováno v:
Psychoneuroendocrinology. 62:54-58
Inflammation, which may be present in a subgroup of individuals with major depressive disorder (MDD), activates the kynurenine metabolic pathway to produce kynurenine metabolites kynurenic acid (KynA) and quinolinic acid (QA). We have previously repo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63f263fb31a613c4e83fa7392f60b93e
https://doi.org/10.1016/j.psyneuen.2015.07.609
https://doi.org/10.1016/j.psyneuen.2015.07.609
Publikováno v:
Neurotoxicity Research. 14:237-248
Impairments in cognitive control, such as those involved in working memory, are associated with dysfunction of the dorsolateral prefrontal cortex (DLPFC) in individuals with schizophrenia. This dysfunction appears to result, at least in part, from ab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba3c4b298026844abeac1608435afe3a
https://doi.org/10.1007/bf03033813
https://doi.org/10.1007/bf03033813
Publikováno v:
Cerebral Cortex. 18:1575-1587
Alterations in the inhibitory circuitry of the dorsolateral prefrontal cortex (DLPFC) in schizophrenia include reduced expression of the messenger RNA (mRNA) for somatostatin (SST), a neuropeptide present in a subpopulation of gamma-aminobutyric acid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac48cc4d732c67a3efcb5377027a561a
https://doi.org/10.1093/cercor/bhm186
https://doi.org/10.1093/cercor/bhm186
Publikováno v:
Bipolar Depression: Molecular Neurobiology, Clinical Diagnosis, and Pharmacotherapy ISBN: 9783319316871
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dbf1ee130ec97c3063c303908cfabdcf
https://doi.org/10.1007/978-3-319-31689-5_8
https://doi.org/10.1007/978-3-319-31689-5_8
Autor:
Brent Wurfel, T.K. Teague, Bart N. Ford, J. R. McMillin, S. A. Bliss, Robert Dantzer, Jonathan Savitz, Hideo Suzuki, Wayne C. Drevets, Harvey M. Morris
Publikováno v:
Translational Psychiatry
A subgroup of individuals with mood and psychotic disorders shows evidence of inflammation that leads to activation of the kynurenine pathway and the increased production of neuroactive kynurenine metabolites. Depression is hypothesized to be causall
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0503e9fc4422a146d7b966adc5af3b9a
https://doi.org/10.1038/tp.2017.88
https://doi.org/10.1038/tp.2017.88
Reduced cortical c-aminobutyric acid (GABA) levels and altered markers for subpopulations of GABA interneurons have been reported in major depressive disorder (MDD) by in-vivo brain imaging and post-mortem histological studies. Subgroups of GABA inte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e3b85dcbbc2d1316d96c96f53fe54ce
https://europepmc.org/articles/PMC3388740/
https://europepmc.org/articles/PMC3388740/
Publikováno v:
Neuropharmacology. 62(3)
Disturbed cortical γ-aminobutyric acid (GABA) neurotransmission in schizophrenia is evident from lamina- and cell type- specific alterations in presynaptic markers. In the dorsolateral prefrontal cortex (DLPFC), these alterations include lower trans
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a39274a9eb1742e76ba64937474f039e
https://pubmed.ncbi.nlm.nih.gov/21215273
https://pubmed.ncbi.nlm.nih.gov/21215273
Publikováno v:
Schizophrenia research. 115(2-3)
Alterations in the inhibitory circuitry of the dorsolateral prefrontal cortex (DLPFC) in schizophrenia include reduced expression of the messenger RNA (mRNA) for somatostatin (SST), a neuropeptide present in a subpopulation of gamma-aminobutyric acid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f42ea69f2275626c9033a4d65de9619
https://pubmed.ncbi.nlm.nih.gov/19804960
https://pubmed.ncbi.nlm.nih.gov/19804960
Publikováno v:
Cortical Deficits In Schizophrenia ISBN: 9780387743509
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9e172d7f432b64fa7818c0d9a2de629f
https://doi.org/10.1007/978-0-387-74351-6_10
https://doi.org/10.1007/978-0-387-74351-6_10