Zobrazeno 1 - 10
of 335
pro vyhledávání: '"Harvey D. Preisler"'
Autor:
Azra Raza, Wei-Tong Hsu, Naomi Galili, Parameswaran Venugopal, Ian Janssen, Jie Yang, Harvey D. Preisler, Jaya Nayini, Betty Gladstone, S. Sivaraman
Publikováno v:
Leukemia Research. 27:529-537
A novel method for simultaneously detecting clonality by FISH, and presence of telomerase activity (telo+ cells) or histone H3 mRNA (H3+) in single cells from a mixed leukemic population is reported. The methods were validated using K562 cells mixed
Publikováno v:
Leukemia & Lymphoma. 44:157-164
The effects of the farnesyl transferase inhibitor FTI-778,123 on the proliferation of normal, MDS, AML, and CML hemopoietic progenitor cells was studied. MDS myeloid and erythroid progenitors are significantly more sensitive to FTI than normal progen
Autor:
L. Fisher, J. Nayini, Harvey D. Preisler, Azra Raza, Biaoru Li, S. Creech, H. Chen, Parameswaran Venugopal
Publikováno v:
Leukemia. 15:1589-1595
P15INK4B methylation and expression was studied in bone marrow cells obtained from normal individuals, from patients who had been cured of lymphoma, and from patients with either MDS or AML. The level of p15 methylation was very low in normal BM cell
Autor:
Shiwen Song, Min Tao, Marc Toofanfard, Biaoru Li, Harvey D. Preisler, Alan Larson, S. Sivaraman, Jaya Nayini, Hong Chen, Parameswaran Venugopal
Publikováno v:
Leukemia & Lymphoma. 41:161-168
Both IL-4 and IL-10 have been shown in vitro to inhibit leukemia cell secretion of IL-1beta, GM-CSF, and TNFalpha, and increase leukemia cell release of IL-1ra. In this study, we have investigated the in vivo effects of IL-4, IL-10, and amifostine on
Autor:
Mary Beth Riley, Stephanie A. Gregory, Raywin Huang, Ahmad Jajeh, Homayoun Shahidi, Sari H. Enschede, Parameswaran Venugopal, Harvey D. Preisler
Publikováno v:
Leukemia & Lymphoma. 40:325-334
Interferon-alfa in combination with cytotoxic chemotherapy has been shown to be effective in treating certain types of non-Hodgkin's lymphoma (NHL) (1). However, there is no published data on upfront induction treatment of aggressive NHL with IFN-alf
Autor:
Jerome Loew, Ahmad Jajeh, Angel G. Galvez, Stephanie A. Gregory, Tanja Andric, Steve Creech, Sefer Gezer, Wei-Tong Hsu, Parameswaran Venugopal, David Slivnick, Solomon S. Adler, Richard A. Larson, Harvey D. Preisler
Publikováno v:
Leukemia Research. 24:671-680
Twenty patients with poor prognosis AML and four patients in the blastic phase of a myeloproliferative disorder were treated with two 'pulses' of therapy each consisting of two doses of high dose araC (separated by 12 h) followed by a single dose of
Autor:
Azra Raza, Harpreet Chopra, Emmanuelle Devemy, Parameswaran Venugopal, Sucai Bi, Xue-Zhi Gao, Harvey D. Preisler
Publikováno v:
Cytokine. 12:1124-1128
The studies described here demonstrate that in vitro processing of cells before extraction of RNA has a major effect on the number and type of cytokine transcripts present within MDS and leukemia cells. Transcripts for GM-CSF, a cytokine whose produc
Autor:
Stephanie A. Gregory, La Tanya Broady-Robinson, Azra Raza, Bruce Dangerfield, B. Yifwayimare Mativi, Parameswaran Venugopal, Harvey D. Preisler, Suneel D. Mundle, Biarou Li, Jonathan D. Cartlidge, Vilasini Shetty
Publikováno v:
British Journal of Haematology. 109:376-381
Myelodysplastic syndromes (MDS) have previously been reported to show competitively high rates of apoptosis and proliferation in the bone marrow (BM). Using a double-labelling technique in the present study, we demonstrated that a significantly high
Autor:
S. Sivaraman, R. Ranganathan, Teresa O'Brien, Xiao-Ke Huang, Raywin Huang, Harvey D. Preisler, A. Jajeh, P. Venugopal, Stephanie A. Gregory, Charuhas Deshpande
Publikováno v:
Microscopy Research and Technique. 50:251-257
Tumor necrosis factor alpha (TNF alpha) is a pleiotropic cytokine that is constitutively produced by leukemic cells in B Chronic Lymphocytic Leukemia (B-CLL). It has been shown to have autocrine and paracrine functions in normal B cells and in B lymp