Zobrazeno 1 - 10
of 334
pro vyhledávání: '"Harvey A. Klein"'
Autor:
Verity J. Ford, Willard N. Applefeld, Jeffrey Wang, Junfeng Sun, Steven B. Solomon, Harvey G. Klein, Jing Feng, Juan Lertora, Parizad Parizi‐Torabi, Robert L. Danner, Michael A. Solomon, Marcus Y. Chen, Charles Natanson
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 13, Iss 15 (2024)
Background High levels of catecholamines are cardiotoxic and associated with stress‐induced cardiomyopathies. Using a septic shock model that reproduces the reversible cardiomyopathy seen over 10 days associated with human septic shock, we investig
Externí odkaz:
https://doaj.org/article/a57db40968374e55a6dd3757f6f640fe
Autor:
Verity J. Ford, Willard N. Applefeld, Jeffrey Wang, Junfeng Sun, Steven B. Solomon, Stanislav Sidenko, Jing Feng, Cynthia Sheffield, Harvey G. Klein, Zu‐Xi Yu, Parizad Torabi‐Parizi, Robert L. Danner, Vandana Sachdev, Michael A. Solomon, Marcus Y. Chen, Charles Natanson
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 13, Iss 15 (2024)
Background Septic shock is associated with increases in end‐diastolic volume (EDV) and decreases in ejection fraction that reverse within 10 days. Nonsurvivors do not develop EDV increases. The mechanism is unknown. Methods and Results Purpose‐br
Externí odkaz:
https://doaj.org/article/af495b8bb43042a29f124e2468971206
Autor:
Willard N. Applefeld, Jeffrey Wang, Steven B. Solomon, Junfeng Sun, Harvey G. Klein, Charles Natanson
Publikováno v:
Applied Sciences, Vol 10, Iss 5, p 1838 (2020)
The finding of toxicity in a meta-analysis of observational clinical studies of transfused longer stored red blood cells (RBC) and ethical issues surrounding aging blood for human studies prompted us to develop an experimental model of RBC transfusio
Externí odkaz:
https://doaj.org/article/5162450c79a649b693130507b816f815
Autor:
Jan Hartmann, Harvey G. Klein
Publikováno v:
Transfusion
Plasma‐derived medicinal products (PDMP) play an integral role in medical treatment and prophylaxis. Most plasma used for manufacturing medicinal products is collected as source plasma by apheresis from donors in dedicated plasma collection centers
Autor:
Willard N. Applefeld, Charles Natanson, Robert L. Danner, Peter Q. Eichacker, Harvey G. Klein, Jeffrey Wang
Publikováno v:
Critical Care and Resuscitation. 22:110-118
Comparative effectiveness research can help guide the use of common, routine medical practices. However, to be safe and informative, such trials must include at least one treatment arm that accurately portrays current practices. While comparative eff
Autor:
Willard N, Applefeld, Jeffrey, Wang, Junfeng, Sun, Benjamin M, Pockros, Steven B, Solomon, Jing, Feng, Thomas, Risoleo, Irene, Cortés-Puch, Aurélie, Gouél-Cheron, Harvey G, Klein, Charles, Natanson
Publikováno v:
Transfusion. 60:698-712
BACKGROUND In experimental canine septic shock, depressed circulating granulocyte counts were associated with a poor outcome and increasing counts with prophylactic granulocyte colony-stimulating factor (G-CSF) improved outcome. Therapeutic G-CSF, in
Publikováno v:
New England Journal of Medicine. 381:150-162
Hemolytic Transfusion Reactions Blood transfusion is very safe; occasionally, however, the recipient has an adverse reaction to the donor blood. This review summarizes the types of transfusion reac...
Autor:
Harvey G. Klein, Juan J Lertora, Thomas F. Risoleo, Mark T. Gladwin, Elmira Alipour, Swati Basu, Willard N. Applefeld, Zoe G. Couse, Daniel B. Kim-Shapiro, Jing Feng, Steven B. Solomon, Robert L. Danner, Jesús Tejero, Charles Natanson, Jeffrey Wang, Vandana Sachdev, Junfeng Sun
Publikováno v:
American journal of physiology. Heart and circulatory physiology. 320(6)
Cell-free hemoglobin (CFH) elevations are a known consequence of clinical sepsis. Using a two-by-two factorial design and extensive physiological and biochemical evidence, we found a direct mechanism of injury related to nitric oxide scavenging leadi
Autor:
Katherine Dura, Nena C Wendzel, James Long, Debrean A. Loy, Nasha Elavia, Divya Gandla, Katie L. Lewis, Harvey G. Klein, Sharon Adams, Harold E. Smith, John D. Roback, Uma S Krishnan, Alexandra Simone, Robert Rivera, Spencer E Grissom, Marina U Bueno, Steven McLaughlin, Maxim Tynuv, Bhavesh Delvadia, Rizaldi Cacanindin, Leslie G. Biesecker, Shahin Shahsavari, Panagiota Karagianni, Patricia A. R. Brunker, Oscar A. Montemayor, Celina Montemayor
Publikováno v:
Vox sanguinisReferences. 116(4)
BACKGROUND AND OBJECTIVES Next generation sequencing (NGS) has promising applications in transfusion medicine. Exome sequencing (ES) is increasingly used in the clinical setting, and blood group interpretation is an additional value that could be ext