Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Harvey A Tatum"'
Autor:
Reem Ghalib, Michelle Treitel, Claudia Martorell, Harvey A Tatum, J. Hanson, Paul J. Thuluvath, E. Cooney, Natarajan Ravendhran, J. Zhao, Vinod K. Rustgi, M. Demicco, J. Zamparo, Eric Lawitz, S. Cohen, Eric Hughes
Publikováno v:
Journal of Viral Hepatitis. 22:658-664
Beclabuvir is a potent, non-nucleoside inhibitor of the HCV NS5B RNA polymerase, with nanomolar activity against HCV genotypes 1, 3, 4, 5 and 6 in vitro. This study evaluated the efficacy and safety of beclabuvir, in combination with peginterferon al
Autor:
Paul J. Thuluvath, Paul Y. Kwo, Harvey A Tatum, John M. Vierling, Paul J. Pockros, Stanislas Pol, Fiona McPhee, Megan Wind-Rotolo, Ola Weiland, Nina Weis, Philip D. Yin, William Sievert, Eric Hughes, Gideon M. Hirschfield, Maribel Rodriguez-Torres, Eric Lawitz, Vinod K. Rustgi, Stephen D. Shafran, Mark S. Sulkowski, Stefan Zeuzem, Gamal Esmat, Marc Bourlière, Gregory T. Everson, Dennis Hernandez, Lawrence Serfaty, Zhaohui Liu, Imam Waked, Wayne Ghesquiere, Michael W. Fried, Steven Schnittman, Maurizia Rossana Brunetto, Stephanie Noviello, Christophe Hézode, Norbert Bräu
Publikováno v:
Gut. 64(6)
To evaluate the safety and efficacy of daclatasvir, an HCV NS5A inhibitor with pangenotypic activity, administered with peginterferon-alfa-2a/ribavirin.In this Phase 2b double-blind, placebo-controlled study, treatment-naive adults with HCV genotype
Autor:
David W. Morris, Dennis Hernandez, Stanislas Pol, Robert Reindollar, Jean-Pierre Bronowicki, Ulysses Diva, Gary A Abrams, Joseph K. Lim, Norbert Bräu, R. Hindes, Christophe Hézode, Steven Schnittman, Megan Wind-Rotolo, Reem Ghalib, Eric Hughes, Vinod K. Rustgi, Paul J. Thuluvath, Harvey A Tatum, Claudia Martorell, Fiona McPhee, G.T. Everson, Philip D. Yin
Publikováno v:
The Lancet. Infectious diseases. 12(9)
Summary Background Several direct-acting antivirals for chronic hepatitis C virus (HCV) infection are available, but they are limited by tolerability and dosing schedules. Once-daily daclatasvir, a potent NS5A replication complex inhibitor, was gener
Autor:
William M. Lee, Timothy J Friel, Laura Kriebel, Geraldine B. Guillon, Mark Fischl, Alexander Monto, Keith W. Kardos, Lisa A. Kurtz, Eugene R. Schiff, Scott E. Eder, Jay Lynn Unangst, Cheryl A. Berne, Alpha T. Banks, Karam Mounzer, Harvey A. Tatum, Michael P. DeMicco, Stephen R. Lee, Gary Feiss, Michele Roehler, Graham Yearwood
Publikováno v:
Journal of virological methods. 172(1-2)
The availability of a highly accurate, rapid, point-of-care test for hepatitis C virus (HCV) may be useful in addressing the problem of under-diagnosis of HCV, by increasing opportunities for testing outside of traditional clinical settings. A new HC
Autor:
Scott Fung, Fiona McPhee, Stanislas Pol, Serena Zaltron, Alnoor Ramji, Victor de Ledinghen, David Cohen, Harvey A Tatum, Stephen D. Shafran, Dominique Larrey, Christophe Hézode, Gloria Taliani, E. Cooney, Peggy Hagens, Nina Weis, Albert Tran, Hugh Harley, Maurizia Rossana Brunetto, Stephanie Noviello, Samuel S. Lee, Gregory J. Dore, Wayne Ghesquiere, Eric Lawitz, Eric Hughes, Simone I. Strasser, Dennis Hernandez, Jacob George
Publikováno v:
Gastroenterology
Gastroenterology, WB Saunders, 2015, 148 (2), pp.355-366.e1. ⟨10.1053/j.gastro.2014.10.007⟩
Gastroenterology, Elsevier, 2015, 148 (2), pp.355-366.e1. ⟨10.1053/j.gastro.2014.10.007⟩
Gastroenterology, WB Saunders, 2015, 148 (2), pp.355-366.e1. ⟨10.1053/j.gastro.2014.10.007⟩
Gastroenterology, Elsevier, 2015, 148 (2), pp.355-366.e1. ⟨10.1053/j.gastro.2014.10.007⟩
International audience; BACKGROUND & AIMS:Twenty-four weeks of treatment with peginterferon and ribavirin for chronic hepatitis C virus (HCV) genotype 2 or 3 infection produces a sustained virologic response (SVR) in 70%-80% of patients. We performed
Autor:
G.J. Dore, Stephen D. Shafran, Nina Weis, Maurizia Rossana Brunetto, Simone I. Strasser, Scott Fung, Daniel Cohen, P. Hagens, Alnoor Ramji, Serena Zaltron, Wayne Ghesquiere, Stanislas Pol, Eric Hughes, E. Lawitz, Harvey A Tatum, E. Cooney, Dominique Larrey, Hugh Harley, Stephanie Noviello, Albert Tran, Christophe Hézode, Gloria Taliani, Jacob George, V. de Ledinghen, Samuel S. Lee
Publikováno v:
Journal of Hepatology. 58:S570-S571
All study medications were discontinued due to adverse events (AEs) in 4%, 4% and 5% of patients, and FDV only was discontinued in 0%, 1% and 3% of patients, respectively. Serious AEs occurred in 6%, 7% and 7% of patients. Grade 3 rash occurred in
Autor:
Vinod K. Rustgi, K. Sims, Ellen Chung, David F. Gardiner, Harvey A Tatum, Dennis M. Grasela, Christophe Hézode, Fiona McPhee, Timothy Eley, Maribel Rodriguez-Torres, Megan Wind-Rotolo, M. Bourlière, Claudio Pasquinelli, Véronique Loustaud-Ratti, X. Wang, G.T. Everson, E.J. Lawitz, Howard J. Schwartz, Shu-Pang Huang, Stanislas Pol, Paul J. Thuluvath, Patrick Marcellin
Publikováno v:
Journal of Hepatology. 58:S573
13.6±1.8 g/dL [8.8–17.5], respectively. After 12W, a complete early virological response was obtained in 34 (83%) boceprevir patients and in 35 (61%) telaprevir patients (p = 0.026). Among 17 boceprevir and 16 telaprevir patients, 14 (82%) and 7 (
Publikováno v:
International Journal of Systematic Bacteriology. 22:19-38
Sixty-two strains of moraxellae and allied bacteria assembled by the Subcommittee on Moraxella and Allied Bacteria of the International Committee on Systematic Bacteriology and distributed by the American Type Culture Collection were examined serolog
Autor:
Elizabeth O. King, Harvey W. Tatum
Publikováno v:
The Journal of Infectious Diseases. 111:85-94
Publikováno v:
Canadian Journal of Microbiology. 18:1477-1482
Pseudomonas acidovorans can be distinguished from P. testosteroni by gas chromatography on the basis of acids detected after 20 h growth on heart infusion agar plates. The data obtained support the findings of other workers that P. acidovorans and P.