Machine learning-based cluster analysis of immune cell subtypes and breast cancer survival

Autor: Zhanwei Wang, Dionyssios Katsaros, Junlong Wang, Nicholetta Biglio, Brenda Y. Hernandez, Peiwen Fei, Lingeng Lu, Harvey Risch, Herbert Yu

Publikováno v: Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)

Abstract Host immunity involves various immune cells working in concert to achieve balanced immune response. Host immunity interacts with tumorigenic process impacting disease outcome. Clusters of different immune cells may reveal unique host immunit

Externí odkaz: https://doaj.org/article/99cf4fdad143454da2285472ed768b03

Bayesian copy number detection and association in large-scale studies

Autor: Stephen Cristiano, David McKean, Jacob Carey, Paige Bracci, Paul Brennan, Michael Chou, Mengmeng Du, Steven Gallinger, Michael G. Goggins, Manal M. Hassan, Rayjean J. Hung, Robert C. Kurtz, Donghui Li, Lingeng Lu, Rachel Neale, Sara Olson, Gloria Petersen, Kari G. Rabe, Jack Fu, Harvey Risch, Gary L. Rosner, Ingo Ruczinski, Alison P. Klein, Robert B. Scharpf

Publikováno v: BMC Cancer, Vol 20, Iss 1, Pp 1-14 (2020)

Abstract Background Germline copy number variants (CNVs) increase risk for many diseases, yet detection of CNVs and quantifying their contribution to disease risk in large-scale studies is challenging due to biological and technical sources of hetero

Externí odkaz: https://doaj.org/article/ca17e3298f774a5f858a0abae0f47a86

Supplement 3 from Fallopian Tube Lesions in Women at High Risk for Ovarian Cancer: A Multicenter Study

Autor: Ie-Ming Shih, Robert Kurman, Robert Soslow, Douglas A. Levine, Russell Vang, Vinita Parkash, Tian-Li Wang, Steven Narod, Harvey Risch, Alpana Kaushiva, Asli Bahadirli-Talbott, Betty J. May, Patricia Shaw, Kala Visvanathan

Supplement 3: Baseline characteristics for the 105 women that underwent extensive sampling of thefallopian tube.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5512aafe70cf11d9ba83744d639c2a5d
https://doi.org/10.1158/1940-6207.22532666.v1

Table S7 from A Transcriptome-Wide Association Study Among 97,898 Women to Identify Candidate Susceptibility Genes for Epithelial Ovarian Cancer Risk

Autor: Jirong Long, Wei Zheng, Paul D.P. Pharoah, Thomas A. Sellers, Georgia Chenevix-Trench, Ellen L. Goode, Andrew Berchuck, Antonis C. Antoniou, Simon A. Gayther, Kristin K. Zorn, Drakoulis Yannoukakos, Anna H. Wu, Alicja Wolk, Emily White, Nicolas Wentzensen, Jeffrey N. Weitzel, Penelope M. Webb, Digna Velez Edwards, Ana Vega, Adriaan Vanderstichele, Elizabeth J. van Rensburg, Shelley S. Tworoger, Nadine Tung, Antonia Trichopoulou, Amanda E. Toland, Marc Tischkowitz, Mads Thomassen, Soo H. Teo, Manuel R. Teixeira, Anthony J. Swerdlow, Rebecca Sutphen, Amanda B. Spurdle, Melissa C. Southey, Honglin Song, Christian F. Singer, Jacques Simard, Weiva Sieh, Priyanka Sharma, Veronica W. Setiawan, Rita K. Schmutzler, Dale P. Sandler, Iwona K. Rzepecka, Mary Anne Rossing, Matti A. Rookus, Isabelle Romieu, Cristina Rodríguez-Antona, Gustavo C. Rodriguez, Harvey Risch, Gad Rennert, Susan J. Ramus, Miquel Angel Pujana, Catherine M. Phelan, Paolo Peterlongo, Tanja Pejovic, Petra H.M. Peeters, Michael T. Parsons, Sue K. Park, Ana Osorio, Håkan Olsson, Sara H. Olson, Olufunmilayo I. Olopade, Edith Olah, Kenneth Offit, Robert L. Nussbaum, Liene Nikitina-Zake, Finn C. Nielsen, Heli Nevanlinna, Susan L. Neuhausen, Marco Montagna, Francesmary Modugno, Melissa A. Merritt, Iain A. McNeish, Lesley McGuffog, Taymaa May, Amalia Mattiello, Douglas A. Levine, Fabienne Lesueur, Goska Leslie, Nhu D. Le, Ava Kwong, Susanne K. Kjaer, Lambertus A. Kiemeney, Linda E. Kelemen, Beth Y. Karlan, Paul James, Anna Jakubowska, Claudine Isaacs, Evgeny N. Imyanitov, David G. Huntsman, Peter J. Hulick, Antoinette Hollestelle, Claus K. Høgdall, Michelle A.T. Hildebrandt, Florian Heitz, Ute Hamann, Jacek Gronwald, Mark H. Greene, Marc T. Goodman, David E. Goldgar, Andrew K. Godwin, Graham G. Giles, Judy Garber, Patricia A. Ganz, Eitan Friedman, George Fountzilas, Renée T. Fortner, Peter A. Fasching, Diana M. Eccles, Douglas F. Easton, Thilo Dörk, Susan M. Domchek, Orland Diez, Joe Dennis, Anna deFazio, Mary B. Daly, Daniel W. Cramer, Fergus J. Couch, Kathleen B.M. Claes, Jenny Chang-Claude, Ian Campbell, Maria A. Caligo, Trinidad Caldes, Ralf Butzow, James Brenton, Line Bjorge, Javier Benitez, Daniel R. Barnes, Rosa B. Barkardottir, Elisa V. Bandera, Banu K. Arun, Hoda Anton-Culver, Irene L. Andrulis, Kirsten B. Moysich, Jamie K. Teer, Brett M. Reid, Jennifer B. Permuth, Yian A. Chen, Hae Kyung Im, Joellen M. Schildkraut, Bingshan Li, Xingyi Guo, Lang Wu, Alicia Beeghly-Fadiel, Yingchang Lu

Variants with P < 5E-8 either in BCAC or OCAC between 42,836,399 and 44,910,520 on the chromosome 17.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1cab58e6e83b40cbbaa4e303fdfbe2c7
https://doi.org/10.1158/0008-5472.22419638.v1

Supplementary Figure Legend from Polymorphisms in Inflammation Pathway Genes and Endometrial Cancer Risk

Autor: Xiao-Ou Shu, Wei Zheng, Qiuyin Cai, Wei Lu, Wanqing Wen, Nurzhan Turmanov, Jone Trovik, Madeleine Corssen, Harvey Risch, Paul Pharoah, Rayna K. Matsuno, Tracy O'Mara, Galina Lurie, Lingeng Lu, Felicity Lose, Camilla Krakstad, Dylyara Kaydarova, Maggie Gorman, Kimberly Howarth, Alexander Hein, Mari K. Halle, Peter A. Fasching, Arif B. Ekici, Douglas Easton, Ingo B. Runnebaum, Alison Dunning, Natalia Dubrowinskaja, An Coosemans, Lieve Coenegrachts, Matthias W. Beckmann, Frederic Amant, Ping-Ping Bao, Helga B. Salvesen, Ying Zheng, Marc T. Goodman, Thilo Dörk, Diether Lambrechts, Herbert Yu, Ian Tomlinson, Deborah Thompson, Jirong Long, Alicia Beeghly-Fadiel, Amanda Spurdle, Yong-Bing Xiang, Ryan J. Delahanty

PDF file - 48K

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1cd250f436a54d05538f0f8539c0bf14
https://doi.org/10.1158/1055-9965.22436205