Critical research gaps and translational priorities for the successful prevention and treatment of breast cancer

Autor: Eccles, SA, Aboagye, EO, Ali, S, Anderson, AS, Armes, J, Berditchevski, F, Blaydes, JP, Brennan, K, Brown, NJ, Bryant, HE, Bundred, NJ, Burchell, JM, Campbell, AM, Carroll, JS, Clarke, RB, Coles, CE, Cook, GJR, Cox, A, Curtin, NJ, Dekker, LV, Silva, IS, Duffy, SW, Easton, DF, Eccles, DM, Edwards, DR, Edwards, J, Evans, DG, Fenlon, DF, Flanagan, JM, Foster, C, Gallagher, WM, Garcia-Closas, M, Gee, JMW, Gescher, AJ, Goh, V, Groves, AM, Harvey, AJ, Harvie, M, Hennessy, BT, Hiscox, S, Holen, I, Howell, SJ, Howell, A, Hubbard, G, Hulbert-Williams, N, Hunter, MS, Jasani, B, Jones, LJ, Key, TJ, Kirwan, CC, Kong, A, Kunkler, IH, Langdon, SP, Leach, MO, Mann, DJ, Marshall, JF, Martin, LA, Martin, SG, Macdougall, JE, Miles, DW, Miller, WR, Morris, JR, Moss, SM, Mullan, P, Natrajan, R, O’Connor, JPB, O’Connor, R, Palmieri, C, Pharoah, PDP, Rakha, EA, Reed, E, Robinson, SP, Sahai, E, Saxton, JM, Schmid, P, Smalley, MJ, Speirs, V, Stein, R, Stingl, J, Streuli, CH, Tutt, ANJ, Velikova, G, Walker, RA, Watson, CJ, Williams, KJ, Young, LS, Thompson, AM

Publikováno v: Eccles, S A, Aboagye, E O, Ali, S, Anderson, A S, Armes, J, Berditchevski, F, Blaydes, J P, Brennan, K, Brown, N J, Bryant, H E, Bundred, N J, Burchell, J M, Campbell, A M, Carroll, J S, Clarke, R B, Coles, C E, Cook, G J, Cox, A, Curtin, N J, Dekker, L V, Dos Santos Silva, I, Duffy, S W, Easton, D F, Eccles, D M, Edwards, D R, Edwards, J, Evans, D, Fenlon, D F, Flanagan, J M, Foster, C, Gallagher, W M, Garcia-closas, M, Gee, J M W, Gescher, A J, Goh, V, Groves, A M, Harvey, A J, Harvie, M, Hennessy, B T, Hiscox, S, Holen, I, Howell, S J, Howell, A, Hubbard, G, Hulbert-williams, N, Hunter, M S, Jasani, B, Jones, L J, Key, T J, Kirwan, C C, Kong, A, Kunkler, I H, Langdon, S P, Leach, M O, Mann, D J, Marshall, J F, Martin, L, Martin, S G, Macdougall, J E, Miles, D W, Miller, W R, Morris, J R, Moss, S M, Mullan, P, Natrajan, R, O'Connor, J P, O'Connor, R, Palmieri, C, Pharoah, P D P, Rakha, E A, Reed, E, Robinson, S P, Sahai, E, Saxton, J M, Schmid, P, Smalley, M J, Speirs, V, Stein, R, Stingl, J, Streuli, C H, Tutt, A N J, Velikova, G, Walker, R A, Watson, C J, Williams, K J, Young, L S & Thompson, A M 2013, ' Critical research gaps and translational priorities for the successful prevention and treatment of breast cancer ', Breast Cancer Research, vol. 15, no. 5, pp. R92 . https://doi.org/10.1186/bcr3493
Eccles, S A, Aboagye, E O, Ali, S, Anderson, A S, Armes, J, Berditchevski, F, Blaydes, J P, Brennan, K, Brown, N J, Bryant, H E, Bundred, N J, Burchell, J M, Campbell, A M, Carroll, J S, Clarke, R, Coles, C E, Cook, G J R, Cox, A, Curtin, N J, Dekker, L V, dos Santos Silva, I, Duffy, S W, Easton, D F, Eccles, D M, Edwards, D R, Edwards, J, Evans, D G, Fenlon, D F, Flanagan, J M, Foster, C, Gallagher, W M, Garcia-Closas, M, Gee, J M W, Gescher, A J, Goh, V, Groves, A M, Harvey, A J, Harvie, M, Hennessy, B T, Hiscox, S, Holen, I, Howell, S J, Howell, A, Hubbard, G, Hulbert-Williams, N, Hunter, M S, Jasani, B, Jones, L J, Key, T J, Kirwan, C C, Kong, A, Kunkler, I H, Langdon, S P, Leach, M O, Mann, D J, Marshall, J F, Martin, L A, Martin, S G, Macdougall, J E, Miles, D W, Miller, W R, Morris, J R, Moss, S M, Mullan, P, Natrajan, R, O'Connor, J P B, O'Connor, R, Palmieri, C, Pharoah, P D P, Rakha, E A, Reed, E, Robinson, S P, Sahai, E, Saxton, J M, Schmid, P, Smalley, M J, Speirs, V, Stein, R, Stingl, J, Streuli, C H, Tutt, A N J, Velikova, G, Walker, R A, Watson, C J, Williams, K J, Young, L S & Thompson, A M 2013, ' Critical research gaps and translational priorities for the successful prevention and treatment of breast cancer ', Breast Cancer Research, vol. 15, no. 5, R92 . https://doi.org/10.1186/bcr3493
Eccles, S A, Aboagye, E O, Ali, S, Anderson, A S, Armes, J, Berditchevski, F, Blaydes, J P, Brennan, K, Brown, N J, Bryant, H E, Bundred, N J, Burchell, J M, Campbell, A M, Carroll, J S, Clarke, R, Coles, C E, Cook, G J R, Cox, A, Curtin, N J, Dekker, L V, dos Santos Silva, I, Duffy, S W, Easton, D F, Eccles, D M, Edwards, D R, Edwards, J, Evans, D G, Fenlon, D F, Flanagan, J M, Foster, C, Gallagher, W M, Garcia-Closas, M, Gee, J M W, Gescher, A J, Goh, V, Groves, A M, Harvey, A J, Harvie, M, Hennessy, B T, Hiscox, S, Holen, I, Howell, S J, Howell, A, Hubbard, G, Hulbert-Williams, N, Hunter, M S, Jasani, B, Jones, L J, Key, T J, Kirwan, C C, Kong, A, Kunkler, I H, Langdon, S P, Leach, M O, Mann, D J, Marshall, J F, Martin, L A, Martin, S G, Macdougall, J E, Miles, D W, Miller, W R, Morris, J R, Moss, S M, Mullan, P, Natrajan, R, O'Connor, J P B, O'Connor, R, Palmieri, C, Pharoah, P D P, Rakha, E A, Reed, E, Robinson, S P, Sahai, E, Saxton, J M, Schmid, P, Smalley, M J, Speirs, V, Stein, R, Stingl, J, Streuli, C H, Tutt, A N J, Velikova, G, Walker, R A, Watson, C J, Williams, K J, Young, L S & Thompson, A M 2013, ' Critical research gaps and translational priorities for the successful prevention and treatment of breast cancer ' Breast Cancer Research, vol. 15, no. 5, R92 . https://doi.org/10.1186/bcr3493

IntroductionBreast cancer remains a significant scientific, clinical and societal challenge. This gap analysis has reviewed and critically assessed enduring issues and new challenges emerging from recent research, and proposes strategies for translat

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