Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Harveen Dhillon"'
Autor:
Lynette C.Y. Chee, David M Ross, Shuh Ying Tan, Joel Wight, George Kannourakis, Miranda Ross, Wei Feng, Ying Jiang, Harveen Dhillon Natarajan, Christine Graham, Christopher Rovaldi, Simon Cooper, Jen L. Salstrom
Publikováno v:
Blood. 140:8181-8183
Autor:
Chee, Lynette C.Y., Ross, David M *, Tan, Shuh Ying *, Wight, Joel, Kannourakis, George, Ross, Miranda *, Feng, Wei *, Jiang, Ying *, Natarajan, Harveen Dhillon *, Graham, Christine *, Rovaldi, Christopher *, Cooper, Simon *, Salstrom, Jen L.
Publikováno v:
In Blood 15 November 2022 140 Supplement 1:8181-8183
Autor:
Vera Hoving, Albertine Donker, Enrikas Vainorius, Harveen Dhillon Natarajan, Jenn Lachey, Simon Cooper, Dorine W. Swinkels, Saskia Schols
Publikováno v:
Blood. 140:2475-2476
Akademický článek
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Autor:
Harveen Dhillon Natarajan, Alejandro Arbelaez, Ying Jiang, Chris Rovaldi, Chun Yew Fong, Tse-Chieh Teh, Claudia Ordonez, Hannah Rose, George Kannourakis, Adrienne Gaggi, John Kwan, David Westerman, Shuhying Tan, James Liang, Jenn Lachey, David M. Ross, Devendra K Hiwase, Lynette C.Y. Chee, Elissa Furutani, Joel Wight, Anish Puliyayil
Publikováno v:
Blood. 138:3675-3675
Background: Myelodysplastic syndromes (MDS) are characterized by ineffective hematopoiesis leading to cytopenias, including anemia and thrombocytopenia. KER-050, a modified activin receptor type IIA inhibitor, is designed to target transforming growt
Autor:
Hoving, Vera *, Donker, Albertine *, Vainorius, Enrikas *, Natarajan, Harveen Dhillon *, Lachey, Jenn, Cooper, Simon *, Swinkels, Dorine W. *, Schols, Saskia *
Publikováno v:
In Blood 15 November 2022 140 Supplement 1:2475-2476
High-fat feeding promotes obesity via insulin receptor/PI3K-dependent inhibition of SF-1 VMH neurons
Autor:
Jeffrey M. Zigman, Tim Klöckener, Andreas Husch, Bradford B. Lowell, Jens C. Brüning, Linda A W Verhagen, Bengt F. Belgardt, Kevin W. Williams, Lars Paeger, Joel K. Elmquist, Tamas L. Horvath, Peter Kloppenburg, Jong Woo Sohn, Simon Hess, Harveen Dhillon, Brigitte Hampel
Publikováno v:
Nature Neuroscience; Vol 14
Nature neuroscience
Nature Neuroscience
Nature neuroscience
Nature Neuroscience
Steroidogenic factor 1 (SF-1)-expressing neurons of the ventromedial hypothalamus (VMH) control energy homeostasis, but the role of insulin action in these cells remains undefined. We show that insulin activates phosphatidylinositol-3-OH kinase (PI3K
Autor:
Ki Woo Kim, Jeffrey M. Zigman, Jennifer W. Hill, Laurent Gautron, Danielle A. Lauzon, Joel K. Elmquist, Charlotte E. Lee, Michelle J. Choi, Jean J. Zhao, Bradford B. Lowell, Jong Woo Sohn, Makoto Fukuda, Yong Xu, Harveen Dhillon
Publikováno v:
Cell Metabolism. 12(1):88-95
SummaryPhosphatidyl inositol 3-kinase (PI3K) signaling in the hypothalamus has been implicated in the regulation of energy homeostasis, but the critical brain sites where this intracellular signal integrates various metabolic cues to regulate food in
Autor:
Tina R. Ivanov, Zoe Hawke, Brad B. Lowell, Harveen Dhillon, David A. Bechtold, Simon M. Luckman
Publikováno v:
The Journal of Neuroscience. 29:14828-14835
The adipose-derived hormone, leptin, was discovered over 10 years ago, but only now are we unmasking its downstream pathways which lead to reduced energy intake (feeding) and increased energy expenditure (thermogenesis). Recent transgenic models have
Autor:
Eleftheria Maratos-Flier, Ren Zhang, Harveen Dhillon, Bradford B. Lowell, Huali Yin, Jeffrey S. Flier, Akihiko Yoshimura
Publikováno v:
Endocrinology. 149:5654-5661
Suppressor of cytokine signaling 3 (Socs3) has been identified as a mediator of central leptin resistance, but the identity of specific neurons in which Socs3 acts to suppress leptin signaling remains elusive. The ventromedial hypothalamus (VMH) was