Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Haruyuki Hongo"'
Autor:
Ayano Tofukuji, Haruyuki Hongo, Takako Nagao, Akemi Sebata, Miwako Suzuki, Yuko Maeno, Eiji Kurosaki, Akiko Fukuda, Tomoyuki Watanabe
Publikováno v:
Advances in Therapy. 40:1884-1898
Autor:
Teruhisa Tokunaga, Haruyuki Hongo, Kyoko Nakamura, Takako Nagao, Ichiro Koga, Tomomi Kitaichi, Akiko Fukuda, Yuko Maeno
Publikováno v:
Advances in Therapy
Introduction Dolutegravir (DTG), a novel HIV-integrase strand transfer inhibitor (INSTI), is usually used with multiple antiretrovirals (ARVs) for treatment of HIV. DTG is now approved as Tivicay tablets in over 120 countries and Triumeq combination
Autor:
Toshiaki Kume, Akinori Akaike, Takeshi Kihara, Yasuhiko Izumi, Haruyuki Hongo, Tetsuhiro Niidome, Hachiro Sugimoto
Publikováno v:
Biochemical and Biophysical Research Communications. 426:94-99
Rotenone, a mitochondrial complex I inhibitor, has been used to generate animal and cell culture models of Parkinson’s disease. Recent studies suggest that microtubule destabilization causes selective dopaminergic neuronal loss. In this study, we i
Autor:
Hachiro Sugimoto, Xiaofeng Wu, Tetsuhiro Niidome, Takeshi Kihara, Haruyuki Hongo, Akinori Akaike
Publikováno v:
British Journal of Pharmacology. 161:33-50
BACKGROUND AND PURPOSE Several clinical trials and in vivo animal experiments have suggested that blockade of angiotensin receptor type 1 (AT1) improves ischaemic outcomes. However, the mechanism(s) underlying these effects has not been elucidated. H
Autor:
William R. Kem, Tetsuhiro Niidome, Hachiro Sugimoto, Xiaofeng Wu, A Akaike, Shun Shimohama, Haruyuki Hongo, Takeshi Kihara, H Shen
Publikováno v:
British Journal of Pharmacology. 161:127-139
BACKGROUND AND PURPOSE Glutamate excitotoxicity may be involved in ischaemic injury to the CNS and some neurodegenerative diseases, such as Alzheimer's disease. Donepezil, an acetylcholinesterase (AChE) inhibitor, exerts neuroprotective effects. Here
Autor:
Takeshi Kihara, Akinori Akaike, Hachiro Sugimoto, Haruyuki Hongo, Tetsuhiro Niidome, Yasuaki Goto
Publikováno v:
European Journal of Pharmacology. 583:84-91
Cholinergic hypothesis and amyloid cascade hypothesis are mainly proposed for Alzheimer's disease; however, the relationship between these hypotheses is poorly understood. To address the question of whether amyloid beta-peptide pathology affects chol
Autor:
Jun Takahashi, Yoshitaka Yano, Ken-ichi Inui, Ikuko Yano, Haruyuki Hongo, Takaaki Kodawara, Y. O. Kishi
Publikováno v:
Journal of pharmaceutical sciences. 98(11)
We propose a simple and practical modeling approach for analysis of the data for myelosuppression after cancer chemotherapy, which can be applied when pharmacokinetic data are not available and several anticancer drugs were simultaneously administere