Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Haruyuki Chaki"'
Autor:
Yasuhiro Morinaka, Haruyuki Chaki, Reiko Tabata, Akihiro Tobe, Mitsuo Egawa, Shuji Morita, Haruko Yamabe, Tomoko Bessho, Kenichi Saito, Mamoru Sugano
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 5:1495-1500
4-Acylaminopyridine derivatives were synthesized and found to have high affinity choline uptake improvement activity. Optimum activity was obtained when the n-propylcarbonyl group was introduced as the acyl moiety. A series of 2-oxo-1-pyrrolidineacet
Autor:
Haruyuki Chaki, Haruko Yamabe, Mamoru Sugano, Shuji Morita, Tomoko Bessho, Reiko Tabata, Ken-Ichi Saito, Mitsuo Egawa, Akihiro Tobe, Yasuhiro Morinaka
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 5:1489-1494
Publikováno v:
ChemInform. 27
Tricycloillicinone (1), a novel tricyclic prenylated C6-C3 compound, has been isolated as a neurotrophic substance from the woods of Illicium tashiroi and its structure has been elucidated by spectroscopic analyses. Compound 1 could increase ChAT act
Publikováno v:
Chemicalpharmaceutical bulletin. 43(12)
Tricycloillicinone (1), a novel tricyclic prenylated C6-C3 compound, has been isolated as a neurotrophic substance from the woods of Illicium tashiroi and its structure has been elucidated by spectroscopic analyses. Compound 1 could increase ChAT act
Autor:
Haruyuki Chaki, Tetsuo Shiba, Shoichi Kusumoto, Tetsuo Shimamoto, Masahiro Imoto, Masaru Inage
Publikováno v:
Clinical Infectious Diseases. 6:478-482
For elucidation of a relationship between chemical structure and biologic activity of lipid A, syntheses of 13 derivatives of glucosamine beta (1-6) disaccharide, which were acylated at 3, 4, and 6'-hydroxyl groups and/or phosphorylated at positions
Autor:
Tetsuo Shiba, Tetsuo Shimamoto, Shoichi Kusumoto, Masahiro Imoto, Masaru Inage, Haruyuki Chaki
Publikováno v:
Tetrahedron Letters. 24:2011-2014
A synthetic route was established to construct the proposed structure of lipid A which consists of β (1–6) glucosamine disaccharide 1,4′-diphosphate O,N-acylated with (R)-3-hydroxy- or (R)-3-acyloxytetradecanoic acid.
Autor:
Tetsuo Shiba, Shoichi Kusumoto, Masaru Inage, Masaaki Nakahata, Haruyuki Chaki, Akira Tai, Yoshiharu Izumi, Tadao Harada
Publikováno v:
Chemistry Letters. 9:1373-1376
Synthesis is described on 6-O-[2-deoxy-2-((R)-3-hydroxytetradecanoylamino)-6-O-tetradecanoyl-β-D-glucopyranosyl]-2-deoxy-2-((R)-3-hydroxytetradecanoylamino)-3,4-di-O-tetradecanoyl-D-glucopyranose which corresponds to the phosphate-less lipid A struc
Publikováno v:
Tetrahedron Letters. 21:3889-3892
6- O -(2-Deoxy-2-myristoylamino-6- O -myristoyl-β-D-glucopyranosyl)-2-deoxy-2-myristoylamino-3,4-di- O -myristoyl-D-glucopyranose ( 2 ) was prepared in a synthetic approach to lipid A which is the active center of bacterial endotoxin.
Publikováno v:
Tetrahedron Letters. 22:2281-2284
1-α-Monophosphate ( 2 ), 4′-monophosphate ( 3 ), and 1-α, 4′-diphosphate ( 4 ) of 6-0-(2-deoxy-2-tetradecanoylamino-6-0-tetradecanoyl-β-D-glucopyranosyl) -2-deoxy-2-tetradecanoylamino-3, 4-di -0-tetradecanoyl-D-glucopyranose were prepared in o
A CONVENIENT PREPARATIVE METHOD OF CARBOHYDRATE PHOSPHATES WITH BUTYLLITHIUM AND PHOSPHOROCHLORIDATE
Publikováno v:
Chemistry Letters. 11:1281-1284
α-Glycosyl phosphates and 4-phosphates of N-acylglucosamine derivatives were prepared in high yields via the reaction of corresponding O-lithium salts with dibenzyl or diphenyl phosphorochloridate at low temperature.