Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Haruyo Yagi"'
Autor:
Zhong Li, Zixuan Lin, Silvia Liu, Haruyo Yagi, Xiurui Zhang, Lauren Yocum, Monica Romero‐Lopez, Claire Rhee, Meagan J. Makarcyzk, Ilhan Yu, Eileen N. Li, Madalyn R. Fritch, Qi Gao, Kek Boon Goh, Benjamen O'Donnell, Tingjun Hao, Peter G. Alexander, Bhushan Mahadik, John P. Fisher, Stuart B. Goodman, Bruce A. Bunnell, Rocky S. Tuan, Hang Lin
Publikováno v:
Advanced Science, Vol 9, Iss 21, Pp n/a-n/a (2022)
Abstract Diseases of the knee joint such as osteoarthritis (OA) affect all joint elements. An in vitro human cell‐derived microphysiological system capable of simulating intraarticular tissue crosstalk is desirable for studying etiologies/pathogene
Externí odkaz:
https://doaj.org/article/74a01e20f19b40abb97cd5398781aced
Autor:
Haruyo Yagi, Shinsuke Kihara, Peter N. Mittwede, Patrick L. Maher, Adam C. Rothenberg, Alyssa D. C. M. Falcione, Antonia Chen, Kenneth L. Urish, Rocky S. Tuan, Peter Geoffrey Alexander
Publikováno v:
Bone & Joint Research, Vol 10, Iss 3, Pp 156-165 (2021)
Aims: Periprosthetic joint infections (PJIs) and osteomyelitis are clinical challenges that are difficult to eradicate. Well-characterized large animal models necessary for testing and validating new treatment strategies for these conditions are lack
Externí odkaz:
https://doaj.org/article/99b4fa32ea5d417e81a4a9117468cb58
Autor:
Meagan J. Makarczyk, Sophie Hines, Haruyo Yagi, Zhong Alan Li, Alyssa M. Aguglia, Justin Zbikowski, Anne-Marie Padget, Qi Gao, Bruce A. Bunnell, Stuart B. Goodman, Hang Lin
Publikováno v:
Biomolecules, Vol 13, Iss 2, p 384 (2023)
Osteoarthritis (OA) is a painful and disabling joint disease affecting millions worldwide. The lack of clinically relevant models limits our ability to predict therapeutic outcomes prior to clinical trials, where most drugs fail. Therefore, there is
Externí odkaz:
https://doaj.org/article/996a34d5ca5449e680fc2fb1ca0c1f96
Autor:
Haruyo Yagi, Antonia F. Chen, David Hirsch, Adam C. Rothenberg, Jian Tan, Peter G. Alexander, Rocky S. Tuan
Publikováno v:
Stem Cell Research & Therapy, Vol 11, Iss 1, Pp 1-12 (2020)
Abstract Introduction There have been limited advances in the treatment of bone and joint infections, which currently involves a combination of surgery and antibiotic administration. There is a timely need in orthopedics to develop more effective and
Externí odkaz:
https://doaj.org/article/2db7c79322d14e198fcaf47885e22ce3
Publikováno v:
Osteoarthritis and Cartilage Open, Vol 2, Iss 3, Pp 100064- (2020)
Reactive oxygen species (ROS) and nitric oxide (NO) have been implicated in chondrocyte senescence and cartilage aging, pathogenesis of osteoarthritis (OA), and rheumatoid arthritis. Naturally occurring polyphenolic compounds (PPCs), such as curcumin
Externí odkaz:
https://doaj.org/article/cd75f363dc41403b9ccee91794f21053
Publikováno v:
Journal of Experimental Orthopaedics, Vol 1, Iss 1, Pp n/a-n/a (2014)
Abstract Background Osteomyelitis is a devastating condition whose treatment relies on the detection of bacteria. The current standard of microbiology culture may not be adequate. Molecular biology based diagnostic procedures for detecting bacteria i
Externí odkaz:
https://doaj.org/article/a6f94b3a561740d0a24da365de411148
Autor:
Zhong Alan Li, Jiangyinzi Shang, Shiqi Xiang, Eileen N. Li, Haruyo Yagi, Kanyakorn Riewruja, Hang Lin, Rocky S. Tuan
Publikováno v:
Organoids; Volume 1; Issue 2; Pages: 135-148
Organoids offer a promising strategy for articular tissue regeneration, joint disease modeling, and development of precision medicine. In this study, two types of human stem cells—primary mesenchymal stem cells (MSCs) and induced pluripotent stem c
Autor:
Hang Lin, Peter G. Alexander, Rocky S. Tuan, Stuart B. Goodman, Bruce A. Bunnell, Qi Gao, Madalyn R. Fritch, Eileen Li, Lauren Yocum, Xiurui Zhang, Haruyo Yagi, Ilhan Yu, Zhong Alan Li, Meagan J. Makarcyzk
Publikováno v:
J Vis Exp
The high prevalence of debilitating joint diseases like osteoarthritis (OA) poses a high socioeconomic burden. Currently, the available drugs that target joint disorders are mostly palliative. The unmet need for effective disease-modifying OA drugs (
Autor:
Patrick L. Maher, Rocky S. Tuan, Antonia F. Chen, Adam C. Rothenberg, Peter G. Alexander, Alyssa D C M Falcione, Shinsuke Kihara, Haruyo Yagi, Peter N. Mittwede, Kenneth L. Urish
Publikováno v:
Bone & Joint Research, Vol 10, Iss 3, Pp 156-165 (2021)
Bone & Joint Research
Bone & Joint Research
Aims Periprosthetic joint infections (PJIs) and osteomyelitis are clinical challenges that are difficult to eradicate. Well-characterized large animal models necessary for testing and validating new treatment strategies for these conditions are lacki
Autor:
David Hirsch, Rocky S. Tuan, Adam C. Rothenberg, Haruyo Yagi, Peter G. Alexander, Jian Tan, Antonia F. Chen
Publikováno v:
Stem Cell Research & Therapy, Vol 11, Iss 1, Pp 1-12 (2020)
Stem Cell Research & Therapy
Stem Cell Research & Therapy
Introduction There have been limited advances in the treatment of bone and joint infections, which currently involves a combination of surgery and antibiotic administration. There is a timely need in orthopedics to develop more effective and less inv