Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Haruyo Sugimoto"'
Autor:
Takeharu Nagai, Haruyo Sugimoto, Akira Nozawa, Kiwamu Takemoto, Yutaka Satou, Naoto Ueno, Tatsuya Sawasaki, Sang-Kee Jung, Kumiko Chiba, Hirotaka Takahashi, Ayako Takeuchi, Satoshi Matsuoka, Takahiro Ishii, Kazuhiro Sakamaki, Koji Koyamada, Ryo Morishita, Akiko Saito, Shuhei Tamate, Toshiya Sakata, Chiyo Takagi, Hajime Shinoda
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. 1863:2766-2783
Activation of caspases is crucial for the execution of apoptosis. Although the caspase cascade associated with activation of the initiator caspase-8 (CASP8) has been investigated in molecular and biochemical detail, the physiological role of CASP8 is
Publikováno v:
Analytical chemistry. 90(21)
We demonstrated the live monitoring of cellular respiration using an ion-sensitive field-effect transistor (ISFET), focusing on different types of living cells, namely cancer and normal cells. In particular, we realized the label-free, real-time, and
Publikováno v:
Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology. 155:266-271
Two mammalian monoamine oxidases (MAO), MAO-A and MAO-B, are similar in primary structures but have unique substrate/inhibitor selectivities. Carp (Cyprinus carpio) contains a MAO enzyme (C-MAO) with properties different from MAO-A and MAO-B. To dete
Autor:
Lars Oreland, Izuru Kakuta, Haruyo Sugimoto, Kazuya Takahashi, Toshio Obata, Hiroyasu Kinemuchi
Publikováno v:
Life Sciences. 80:1094-1099
We have previously reported that carp (Cyprinus carpio) tissue mitochondria contain a novel form of monoamine oxidase (MAO), which belongs neither to MAO-A nor to MAO-B of the mammalian enzyme. This conclusion results from the findings that the carp
Publikováno v:
NeuroToxicology. 25:325-335
Semicarbazide-sensitive amine oxidase (SSAO, EC 1.4.3.6) is a group of enzymes highly sensitive to inhibition by semicarbazide. This high sensitivity distinguishes these enzymes from monoamine oxidase (MAO). Various mammalian tissues contain membrane
Autor:
Toshiya Sakata, Hiroaki Inui, Eiko Kikuchi, Haruyo Sugimoto, Jinji Mizuno, Kaori Noguchi, Akiko Saito
Publikováno v:
Analytical chemistry. 85(14)
In this study, we have proposed and demonstrated experimentally a novel monitoring device of single mouse embryo activity after in vitro fertilization (IVF) using a semiconductor-based field effect transistor (FET). The FET biosensor realized to dete
Autor:
Shoji Yamaoka, Ayako Arai, Naoki Yamamoto, Yasunori Saitoh, Mayumi Takahashi, Haruyo Sugimoto, Osamu Miura, Mizuho Nonaka, Tohti Amet, Shin Uota
Publikováno v:
Experimental cell research. 315(2)
Adult T-cell leukemia (ATL) is a fatal lymphoproliferative disease that develops in human T-cell leukemia virus type I (HTLV-I)-infected individuals. Despite the accumulating knowledge of the molecular biology of HTLV-I-infected cells, effective ther
Autor:
Takao Masuda, Naoki Yamamoto, Haruyo Sugimoto, Atae Utsunomiya, Yasunori Saitoh, Shoji Yamaoka, Xiaohua Qi, Johji Inazawa, Katsuyoshi Matsubara, Vicente Javier Martínez Bruyn, M. Zahidunnabi Dewan, Issei Imoto, Norio Yamamoto, Toshiki Watanabe, Tatsuya Saitoh, Yuki Iwasaki
Publikováno v:
Blood. 111(10)
The nuclear factor-κB (NF-κB) transcription factors play important roles in cancer development by preventing apoptosis and facilitating the tumor cell growth. However, the precise mechanisms by which NF-κB is constitutively activated in specific c
Autor:
Bo Blomgren, Camilla Göktürk, Mats Sjoquist, Godfried M. Roomans, Haruyo Sugimoto, Lars Oreland, Karin Forsberg-Nilsson
Publikováno v:
American journal of hypertension. 20(7)
Background: The catalytic activity of semicarbazide-sensitive amine oxidase (SSAO) is increased in diabetes, as well as in other disorders of cardiovascular origin. Our hypothesis is that SSAO is involved in the synthesis or maturation of elastin in
Autor:
Karin Forsberg-Nilsson, Camilla Göktürk, Jenny Nordquist, Haruyo Sugimoto, Lars Oreland, Joakim Nilsson
Publikováno v:
Biochemical and biophysical research communications. 325(3)
Semicarbazide-sensitive amine oxidase (SSAO) activity in plasma is increased in diabetes, and in particular, in diabetic patients with vascular complications. It has been speculated that SSAO is involved in the development of such complications due t