Zobrazeno 1 - 10
of 93
pro vyhledávání: '"Haruyasu Kinashi"'
Autor:
Yosi Nindita, Zhisheng Cao, Amirudin Akhmad Fauzi, Aiko Teshima, Yuya Misaki, Rukman Muslimin, Yingjie Yang, Yuh Shiwa, Hirofumi Yoshikawa, Michihira Tagami, Alexander Lezhava, Jun Ishikawa, Makoto Kuroda, Tsuyoshi Sekizuka, Kuninobu Inada, Haruyasu Kinashi, Kenji Arakawa
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-11 (2019)
Abstract Streptomyces rochei 7434AN4 produces two structurally unrelated polyketide antibiotics, lankacidin and lankamycin, and carries three linear plasmids, pSLA2-L (211 kb), -M (113 kb), and -S (18 kb), whose nucleotide sequences were previously r
Externí odkaz:
https://doaj.org/article/38545547c5a644cd8f4d1d735a5d7b7d
Autor:
Yuya Misaki, Shouji Yamamoto, Toshihiro Suzuki, Miyuki Iwakuni, Hiroaki Sasaki, Yuzuru Takahashi, Kuninobu Inada, Haruyasu Kinashi, Kenji Arakawa
Publikováno v:
Frontiers in Microbiology, Vol 11 (2020)
Streptomyces rochei 7434AN4, a producer of lankacidin (LC) and lankamycin (LM), carries many regulatory genes including a biosynthesis gene for signaling molecules SRBs (srrX), an SRB receptor gene (srrA), and a SARP (Streptomyces antibiotic regulato
Externí odkaz:
https://doaj.org/article/6a3177e39e0d4cbd8680674c1796b6e8
Autor:
Haruyasu Kinashi, Yuya Misaki, Aiko Teshima, Yosi Nindita, Kenji Arakawa, Yuji Konaka, Hisashi Kondo, Yasuhiro Itakura, Yu Tanaka, Tsugumi Tonokawa
Publikováno v:
Bioscience, biotechnology, and biochemistry. 85(1)
To elucidate the gross lankamycin biosynthetic pathway including two cytochrome P450 monooxygenases, LkmK and LkmF, we constructed two double mutants of P450 genes in combination with glycosyltransferase genes, lkmL and lkmI. An aglycon 8,15-dideoxyl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8007068ba3781f0ed4c0e5acfa433545
https://pubmed.ncbi.nlm.nih.gov/33577670
https://pubmed.ncbi.nlm.nih.gov/33577670
Autor:
Keisuke Hara, Toshihiro Suzuki, Asako Umeshiro, Haruyasu Kinashi, Kenji Arakawa, Yu Yabuuchi, Yosi Nindita, Yusuke Yamauchi
Publikováno v:
Journal of Bioscience and Bioengineering. 126:145-152
Reinvestigation of the metabolite profile in a disruptant of the quinoprotein dehydrogenase (orf23) gene revealed that the Orf23 protein catalyzes dehydrogenation of the C23-C25 lactate moiety to pyruvate during lankacidin biosynthesis in Streptomyce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c28d60b4ee75d96724c793bf6a32353c
https://doi.org/10.1016/j.jbiosc.2018.03.006
https://doi.org/10.1016/j.jbiosc.2018.03.006
Autor:
Hirofumi Yoshikawa, Aiko Teshima, Yuya Misaki, Kenji Arakawa, Makoto Kuroda, Yuh Shiwa, Kuninobu Inada, Michihira Tagami, Rukman Muslimin, Alexander Lezhava, Jun Ishikawa, Amirudin Akhmad Fauzi, Yingjie Yang, Yosi Nindita, Tsuyoshi Sekizuka, Haruyasu Kinashi, Zhisheng Cao
Publikováno v:
Scientific Reports
Scientific Reports, Vol 9, Iss 1, Pp 1-11 (2019)
Scientific Reports, Vol 9, Iss 1, Pp 1-11 (2019)
Streptomyces rochei 7434AN4 produces two structurally unrelated polyketide antibiotics, lankacidin and lankamycin, and carries three linear plasmids, pSLA2-L (211 kb), -M (113 kb), and -S (18 kb), whose nucleotide sequences were previously reported.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ffa5ce9ceb7344a3cb6cf4905f3f41f9
http://europepmc.org/articles/PMC6662830
http://europepmc.org/articles/PMC6662830
Autor:
Yuh Shiwa, Alexander Lezhava, Kenji Arakawa, Yosi Nindita, Yingjie Yang, Haruyasu Kinashi, Michihira Tagami, Zhisheng Cao, Hirofumi Yoshikawa
Publikováno v:
Molecular Microbiology. 95:846-858
Summary Streptomyces rochei 7434AN4 carries three linear plasmids, pSLA2-L (211 kb), pSLA2-M (113 kb) and pSLA2-S (18 kb), their complete nucleotide sequences having been determined. Restriction and sequencing analysis revealed that the telomere sequ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ac45d0c7176e773b4fd61babb3a4cd05
https://doi.org/10.1111/mmi.12904
https://doi.org/10.1111/mmi.12904
Autor:
Tsuyoshi Nakano, Yukari Totsuka, Hirokazu Fukuda, Masafumi Yamamoto, Azusa Takahashi-Nakaguchi, Haruyasu Kinashi, Takeji Takamura-Enya, Yuko Matsushima-Hibiya, Masaya Ono
Publikováno v:
Toxicon. 63:55-63
The Streptomyces coelicolor A3(2) genome encodes a possible secretion protein, SCO5461, that shares a 30% homology with the activity domains of two toxic ADP-ribosyltransferases, pierisins and mosquitocidal toxin. We found ADP-ribosylating activity f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf81e4a59323b2aeb7bc18889b8eccd4
https://doi.org/10.1016/j.toxicon.2012.11.019
https://doi.org/10.1016/j.toxicon.2012.11.019
Publikováno v:
Tetrahedron. 67:5199-5205
Lankamycin, a 14-membered macrolide antibiotic, contains a 3-hydroxy-2-butyl side chain at C-13. To analyze the function of lkmE, which encodes type-II thioesterase in the lankamycin cluster, we carried out a gene disruption experiment. Disruption of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::48cb46018017b76de1fc4f4da87b53db
https://doi.org/10.1016/j.tet.2011.05.047
https://doi.org/10.1016/j.tet.2011.05.047
Autor:
Susumu Mochizuki, Satoru Endo, Yosi Nindita, Toru Kurokawa, Yingjie Yang, Yoshifumi Takahama, Kenji Arakawa, Haruyasu Kinashi
Publikováno v:
Bioscience, Biotechnology, and Biochemistry. 75:1147-1153
The 113,463-bp nucleotide sequence of the linear plasmid pSLA2-M of Streptomyces rochei 7434AN4 was determined. pSLA2-M had a 69.7% overall GC content, 352-bp terminal inverted repeats with 91% (321/352) identity at both ends, and 121 open reading fr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7fb75b03a9da498d9626a8c6ee79f6e5
https://doi.org/10.1271/bbb.110054
https://doi.org/10.1271/bbb.110054
Publikováno v:
Archives of Microbiology. 193:299-306
We have comprehensively analyzed the linear chromosomes of Streptomyces griseus mutants constructed and kept in our laboratory. During this study, macrorestriction analysis of AseI and DraI fragments of mutant 402-2 suggested a large chromosomal inve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef4e6eead5c31816bbf14505d8ca31b5
https://doi.org/10.1007/s00203-010-0674-5
https://doi.org/10.1007/s00203-010-0674-5