Zobrazeno 1 - 10
of 74
pro vyhledávání: '"Harutoshi, Kizaki"'
Publikováno v:
In Japanese Journal of Pharmacology 1999 79(2):177-183
Autor:
Gen-yuki Yamane, Kazumasa Ohta, Harutoshi Kizaki, Morio Tonogi, Sachiko Takaki, Yasuhiro Kizu
Publikováno v:
Oral Radiology. 28:75-81
Radiation-induced xerostomia is a frequent consequence of radiotherapy for head and neck cancer, but its mechanisms remain unclear. Osteopontin (OPN), a highly phosphorylated glycoprotein, has been shown to be involved in the modulation of inflammato
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bac8a4ff652c4ea6f9d3321a28b2f6d6
https://doi.org/10.1007/s11282-012-0089-x
https://doi.org/10.1007/s11282-012-0089-x
Publikováno v:
The Bulletin of Tokyo Dental College. 52:21-29
The 5'-AMP-activated protein kinase (AMPK) is a key enzyme in the protection of cells during energy crisis. AMPK is a heterotrimer consisting of a catalytic α (α1, 2) subunit and two regulatory subunits, β (β1, 2) and γ (γ1-3). To elucidate the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef1d7fb9ccf749cb7e033fddd254b2aa
https://doi.org/10.2209/tdcpublication.52.21
https://doi.org/10.2209/tdcpublication.52.21
Publikováno v:
International Endodontic Journal. 41:197-203
AIM To investigate the effects of hydrogen peroxide on cell viability and expression and activation of AMP-activated protein kinase (AMPK) in rat dental pulp cell line RPC-C2A. METHODOLOGY RPC-C2A cells derived from rat dental pulp were maintained in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79425f5aa0da45506a78e19d41d29a63
https://doi.org/10.1111/j.1365-2591.2007.01337.x
https://doi.org/10.1111/j.1365-2591.2007.01337.x
Autor:
Kazumasa Ohta, Harutoshi Kizaki, Yutaka Sato, Ayako Ishikawa, Koji Sakiyama, Rintarou Okoshi, Yoshinobu Ide
Publikováno v:
Journal of Oral Biosciences. 50:51-58
AMP-activated protein kinase (AMPK) acts as a fuel gauge during musclar exercise and stress-induced energy crisis. The function of the masseter muscle changes during postnatal development, along with an alteration in the type of muscle fibers. We inv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::85ae6ebdeb5b510af039748f700eddce
https://doi.org/10.1016/s1349-0079(08)80018-7
https://doi.org/10.1016/s1349-0079(08)80018-7
Autor:
Kazumasa Ohta, Y. Fukuyama, Harutoshi Kizaki, Rintarou Okoshi, Masataka Suehara, Kan-Ichi Nakagawa
Publikováno v:
Journal of Dental Research. 86:903-907
AMP-activated protein kinase (AMPK) is a stress-responsive enzyme involved in cell adaptation to an energy crisis. We hypothesized that hypoxia suppresses oxidative phosphorylation and ATP production, resulting in AMPK activation to protect cells. We
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe7a528a3e04d02f958db92f0d2a79b9
https://doi.org/10.1177/154405910708600919
https://doi.org/10.1177/154405910708600919
Publikováno v:
Oral microbiology and immunology. 22(4):240-247
Introduction: Streptococcus sobrinus exhibits marked dextran-dependent aggregation mediated by glucan-binding proteins (GBPs). In contrast to Streptococcus mutans, in which the gbpC gene responsible for dextran-dependent aggregation of this organism
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::800032dba18a605392274e1d825bf7dc
http://hdl.handle.net/10130/531
http://hdl.handle.net/10130/531
Autor:
Kazumasa Ohta, Harutoshi Kizaki, Yutaka Sato, Ayako Ishikawa, Rintarou Okoshi, Maiko Wakabayashi
Publikováno v:
Biomedical Research. 28:33-42
Geldanamycin, a heat-shock protein 90 (Hsp90)-binding agent, modulates various cellular activities. The present study found that, although geldanamycin by itself had no effect on thymocyte viability, it induced apoptosis in thymocytes with a reductio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e79bf5d86de4f5f7ee08ebb802c147e5
https://doi.org/10.2220/biomedres.28.33
https://doi.org/10.2220/biomedres.28.33
Publikováno v:
Oral Microbiology and Immunology. 21:32-41
Background/aims: The past few decades have seen the isolation of certain glucosyltransferases and a number of proteins from mutans streptococci. Some of these proteins have been shown to possess glucan-binding capabilities which confer an important v
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aab98f374c20a8b0ba412106c8ca63d8
https://doi.org/10.1111/j.1399-302x.2005.00251.x
https://doi.org/10.1111/j.1399-302x.2005.00251.x
Publikováno v:
Journal of Oral Biosciences. 47(2):171-174
Streptococcus mutans glucan-binding protein C encoded by the gbpC gene is an important virulent factor in human dental caries. However, a nonsense mutation and several nucleotide substitutions in the gbpC gene have been detected in strain GS-5. There
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94787180fcdd362cd01407df655bc457
http://hdl.handle.net/10130/369
http://hdl.handle.net/10130/369