Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Haruo Shibuya"'
Autor:
Yasuko Kurio, Yachiyo Takahashi, Masako Okawa, Hiroko Tobai, Haruo Shibuya, Keiko Ikemoto, Machiko Sugiura, Sayaka Hirano, Yuko Suzuki
Publikováno v:
Sleep and Biological Rhythms. 4:175-178
Light therapy is well accepted as an effective treatment for insomnia. We encountered a patient with epilepsy, cerebral palsy and severe motor and intellectual disabilities accompanied by severe behavioral disturbances. The sleep-wake cycle of this p
Autor:
Michiko Nakamura, Masashi Takeichi, Yasuo Suzuki, Ichiro Kusumi, Yasuyuki Fukumaki, Takeo Yoshikawa, Takashi Asada, Takuya Kojima, Takuya Ueno, Masanari Itokawa, Hiroshi Kunugi, Shinichiro Nanko, Sakae Takahashi, Yohtaro Numachi, Nakao Iwata, Akira Imamura, Tsuyuka Ohtsuki, Sunao Kaneko, Hiroshi Ujike, Ryota Hashimoto, Toshiya Inada, Hiroshi Fukuzako, Hiroki Shibata, Haruo Shibuya, Naoshi Kaneko, Shigeto Yamada, Hiroshi Yoneda, Tomoko Toyota, Takahiro Shinkai, Tadao Arinami, Kazuo Yamada, Mutsuo Harano, Yukitaka Morita, Ohmori Osamu, Tatsuyuki Muratake, Takafumi Hori, Mari Mineta, Tohru Ohnuma, Toshiyuki Someya, Yuji Tanaka, Norio Yasui-Furukori, Norio Ozaki, Shin ich Niwa, Yujitno Okazaki, Heii Arai, Hisashi Higuchi, Tomo Hashiguchi, Tsukasa Koyama, Koichi Ohara, Hiroki Ishiguro, Hirokazu Tachikawa, Kenshiro Ohara
Publikováno v:
The American Journal of Human Genetics. 77:937-944
The Japanese Schizophrenia Sib-Pair Linkage Group (JSSLG) is a multisite collaborative study group that was organized to create a national resource for affected sib pair (ASP) studies of schizophrenia in Japan. We used a high-density single-nucleotid
Autor:
Kimiko Yoshida, Shigeru Tanabu, Keiko Ikemoto, Haruo Shibuya, Kazuhisa Ishibashi, Koichi Ohara
Publikováno v:
Progress in Neuro-Psychopharmacology and Biological Psychiatry. 27:347-350
The authors studied the effect of aging and the CYP2D6*10 polymorphism on the plasma haloperidol (HAL) concentration after chronic administration of HAL. Subjects were 110 Japanese patients (66 male) treated orally with HAL. Venous blood was obtained
Autor:
Masahiro Nankai, Yasuhiko Sudo, Yoshiro Okubo, Akihiro Takano, Fumihiko Yasuno, Kazuhiko Nakayama, Tetsuya Ichimiya, Jun Maeda, Haruo Shibuya, Tetsuya Suhara, Makoto Inoue
Publikováno v:
Biological Psychiatry. 51:715-722
Background: Several lines of studies have suggested the involvement of serotonin transporter (5-HTT) in the pathophysiology of mood disorders. The aim of this study was to examine whether 5-HTT binding was altered in patients with mood disorders usin
Autor:
Koji Saito, Joanne M.A. Meerabux, Tomoko Toyota, Haruo Shibuya, Takeo Yoshikawa, Kazuo Yamada, Masahiro Nankai, Eiji Hattori
Publikováno v:
American Journal of Medical Genetics. 114:84-92
Chromosome 16p13 has been shown to display modest linkage signals for mood disorders in a number of studies. An interesting candidate gene in this region is the adenylate cyclase (AC) type 9 gene (ADCY9). ACs are critical in neuronal signaling, and p
Publikováno v:
Psychiatric Genetics. 9:135-138
Catechol-O-methyltransferase (COMT) is a key modulator of dopaminergic and noradrenergic neurotransmission. There is a functional polymorphism of the COMT gene, Val108Met in the soluble form of the enzyme (Vall58Met in the membrane-bound form). Invol
Autor:
Toshikazu Saito, Hiroki Ishiguro, Shigeru Akazawa, Hiroshi Mitushio, Haruo Shibuya, Hideo Mifune, Kunimaro Tada, Tadao Arinami, Minoru Enomoto, Michio Toru
Publikováno v:
Alcoholism: Clinical and Experimental Research. 23:1281-1284
Background: Involvement of the serotoninergic system (S/S) in alcoholism has been suggested in both mice and humans. Previous studies have suggested the S/S genotype of the serotonin transporter gene promoter polymorphism to be associated with severe
Publikováno v:
Psychiatry Research. 85:209-213
The activity of dopamine-containing neurons in the ventral tegmental area and nucleus accumbens may play a role in alcoholism. Cholecystokinin (CCK) co-exists in a large proportion of A10 dopamine neurons to exert some effect on dopamine-induced beha
Publikováno v:
Neurochemistry International. 29:279-287
We measured [125I] iomazenil binding, labeling the central-type benzodiazepine receptor in 37 discrete rat brain areas following single (7.5 mg/kg, i.p.) and repeated (7.5 mg/kg/day x 14 days, i.p.) treatment with phencyclidine (PCP), a non-competiti
Autor:
Hiromitsu Shimizu, Haruo Shibuya, Yoshiro Ookubo, Michio Toru, Masanari Itokawa, Katsuya Ota, Hideo Hamaguchi, Junichi Aoki, Atsushi Iwawaki, Tadao Arinami
Publikováno v:
American Journal of Medical Genetics. 67:133-138
The dopamine D2 receptor gene is a candidate gene for schizophrenia because the potency of certain neuroleptics correlates with their affinity for this receptor. Case-control studies in 291 schizophrenics, 78 patients with affective disorders, and 57