Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Haruo Iwabuchi"'
Publikováno v:
Mass Spectrometry (2187-137X); 2023, Vol. 12, p1-5, 5p
Autor:
Naoto Chigira, Ryuhei Uruno, Takahiro Okada, Teruaki Hasegawa, Yoshitsugu Amano, Masaki Nakamura, Haruo Iwabuchi, Yuki Nonaka, Ryoji Matsuoka, Maho Iwamura, Fumiko Dai
Publikováno v:
Tetrahedron. 72:5456-5464
2,2′-Bipyridines having two lactoside- or maltoside-appendages were prepared and then, complexed with ferrous ion to afford the corresponding tris-bipyridine ferrous complexes presenting hexavalent lactoside/maltoside clusters. Each of these comple
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a36a6534fc044991c7c7c94edfd4b38e
https://doi.org/10.1016/j.tet.2016.07.026
https://doi.org/10.1016/j.tet.2016.07.026
Autor:
Takahiro Okada, Teruaki Hasegawa, Haruo Iwabuchi, Yuki Nonaka, Ryoichi Koyama, Maho Iwamura, Ryoji Matsuoka, Fumiko Dai, Masaki Nakamura
Publikováno v:
Bulletin of the Chemical Society of Japan. 89:617-625
We synthesized rhodamine-labeled β-lactoside and assessed its rotatory diffusion rates in aqueous media containing various oligosaccharides through fluorescence intensity distribution analysis-pola...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::796f496775b6dac75b392d53f48524fe
https://doi.org/10.1246/bcsj.20150369
https://doi.org/10.1246/bcsj.20150369
Autor:
Minoru Oguchi, Thomas Fischer, Minoru Uchiyama, Juergen Mueller, Hiroko Koda, Haruo Iwabuchi, Takashi Izumi, Naotoshi Yamamura, Osamu Okazaki
Publikováno v:
Drug Metabolism and Disposition. 39:1311-1319
The in vitro metabolism of rivoglitazone, (RS)-5-{4-[(6-methoxy-1-methyl-1H-benzimidazol-2-yl)methoxy]benzyl}-1,3-thiazolidine-2,4-dione monohydrochloride, a novel thiazolidinedione (TZD) peroxisome proliferator-activated receptor γ selective agonis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9cf28e734dc4b500d99cfff5c1d49fa8
https://doi.org/10.1124/dmd.111.038729
https://doi.org/10.1124/dmd.111.038729
Autor:
Tomoe Tanimoto, Naoki Kiyosawa, Sunao Manabe, Osamu Okazaki, Klaus-Peter Adam, Yosuke Ando, Takashi Yamoto, John A. Ryals, Michael V. Milburn, James E. Weiel, Wataru Saitoh, Haruo Iwabuchi, Atsushi Sanbuissho, Lining Guo, Makoto Takei
Publikováno v:
Toxicological Sciences
Ethylene glycol monomethyl ether (EGME) is a widely used industrial solvent known to cause adverse effects to human and other mammals. Organs with high metabolism and rapid cell division, such as testes, are especially sensitive to its actions. In or
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4673cc0ed82f2e531e7093f2686438e9
https://doi.org/10.1093/toxsci/kfq211
https://doi.org/10.1093/toxsci/kfq211
Autor:
Minoru Oguchi, Haruo Iwabuchi, Juergen Mueller, Takashi Izumi, Minoru Uchiyama, Thomas Fischer, Naotoshi Yamamura, Hiroko Koda
Publikováno v:
Journal of the Mass Spectrometry Society of Japan. 58:1-11
The in vitro metabolism of rosiglitazone (RGZ) was studied in freshly isolated human, rat, and monkey hepatocytes. The metabolites of [14C]RGZ produced by incubation with hepatocytes were detected by radioactivity detection high-performance liquid ch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3ff696615f625781ff3449307b19c94d
https://doi.org/10.5702/massspec.58.1
https://doi.org/10.5702/massspec.58.1
Autor:
Takashi Izumi, Maki Goto, Hisako Tanaka, Shin-ichi Inaba, Makoto Takahashi, Haruo Iwabuchi, Tomoko Ikeda
1. Disposition and metabolism of CS-0777 (1-{5-[(3R)-3-amino-4-hydroxy-3- methylbutyl]-1-methyl-1H-pyrrol-2-yl}-4-(4-methylphenyl) butan-1-one), a selective sphingosine 1-phosphate receptor-1 modulator under development for autoimmune conditions was
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40f5565753aafdc646029efaf0e4f23e
Autor:
Hiroaki Miida, Minoru Uchiyama, Yukari Shibaya, Ayako Hara, Shingo Arakawa, Kazunori Fujimoto, Hiroaki Yasumo, Sunao Manabe, Yosuke Ando, Wataru Takasaki, Haruo Iwabuchi, Takashi Yamoto
Publikováno v:
Drug Metabolism and Disposition. 34:1495-1501
Glutathione S -transferase Mu 1 (GSTM1) has been regarded as one of the key enzymes involved in phase II reactions in the liver, because of its high expression level. In this study, we generated mice with disrupted glutathione S -transferase Mu 1 gen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0326527c3f845ecec52736ade6e20835
https://doi.org/10.1124/dmd.106.010009
https://doi.org/10.1124/dmd.106.010009
Publikováno v:
Drug Metabolism and Disposition. 34:1102-1108
We identified human UDP-glucuronosyltransferase (UGT) isoforms responsible for producing dihydrotestosterone (DHT) diglucuronide, a novel glucuronide in which the second glucuronosyl moiety is attached at the C2' position of the first glucuronosyl mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be6f432dfc41615ed4ba58eebf89faaa
https://doi.org/10.1124/dmd.106.009621
https://doi.org/10.1124/dmd.106.009621
Publikováno v:
Drug Metabolism and Pharmacokinetics. 20:282-293
Androgens (androsterone, dihydrotestosterone and testosterone) and estrogens (estradiol, estriol and estrone) were incubated with liver microsomes from rats, dogs, monkeys and humans in the presence of uridine diphosphoglucuronic acid (UDPGA), and th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2576a2ad87fc9e1931baecb0e22631b
https://doi.org/10.2133/dmpk.20.282
https://doi.org/10.2133/dmpk.20.282