Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Haruo Isomura"'
Autor:
Tadashi Iizuka, Wataru Sakamoto, Hiroshi Tamai, Haruo Isomura, Yusuke Osaki, Kazuhiko Takahashi, Gen Tatebe, Michio Komai, Jun Nishihira, Katsutoshi Fujie
Publikováno v:
Osteoporosis International. 16:1604-1610
Reactive oxygen species (ROS) may contribute to aging and osteoporosis resulting from marked decreases in plasma antioxidants in aged osteoporotic women. On the other hand, high-dose vitamin K2 (menaquinone-4: menatrenone, MK-4) supplementation has b
Autor:
Hiroshi Izumi, Haruo Isomura, Katsutoshi Fujie, Kazuhiko Takahashi, Kei Nakao, Wataru Sakamoto
Publikováno v:
Annals of Nutrition and Metabolism. 49:149-154
Aims: In experimental animals we investigated the relationship of coffee consumption with risk factors of atherosclerosis such as cholesterol, homocysteine, oxidative stress and inflammatory cytokines. Methods: Forty-eight male Wistar rats were assig
Autor:
Hiroshi Izumi, Haruo Isomura, Jun Nishihira, Nobuo Inoue, Gen Takebe, Kouichi Shibata, Wataru Sakamoto, Kazuhiko Takahashi, Tadashi Iizuka, Katsutoshi Fujie
Publikováno v:
Toxicology. 197(2)
Osteoporosis is associated with many etiological causes such as nutrition, cytokines, hormones, and aging. Recently, reactive oxygen species (ROS) are considered to be responsible for the aging process and osteoporosis. We investigated the relationsh
Autor:
Jun Nishihira, Mitsuru Ozaki, Susumu Yukawa, Wataru Sakamoto, Haruo Isomura, Katsutoshi Fujie
Publikováno v:
Toxicology. 183(1-3)
We examined whether coffee or chlorogenic acid inhibits 8-hydroxydeoxyguanosine (8-OHdG), one of the major forms of oxidative DNA damage, in vivo and in vitro. Forty-eight male Wistar rats were assigned to three treatment groups: a control-diet group
Autor:
Bénédicte Fontaine-Bisson, Thomas Schettgen, A. Idrissi-Oudghiri, Kei Nakao, D. Hornig, A. Derouiche, Jochen Bausch, Hiroshi Izumi, Matthias W. Beckmann, Hans Drexler, M. S. Corbalán, Birgitta Kütting, J.M. Lecerf, A. Adlouni, Amelia Marti, George Grant, Reg Fletcher, Patrick Couture, Kazuhiko Takahashi, Julie Robitaille, M. Raghunath, Wataru Sakamoto, André Tchernof, Haruo Isomura, Ulf-W. Wiegand, George Bertsias, Stefan Hartmann, Ioannis N. Mammas, Marina Carbonaro, A. Drissi, Jürgen Angerer, Rune Blomhoff, M. Cherki, Marie-Claude Vohl, Katsutoshi Fujie, Anthony Kafatos, Jürgen Bock, L. Venu, G.V. Vidya Sagar, D. Sreeramulu, Miguel Ángel Martínez-González, Luis Forga, D. Hartmann, Alvaro Alonso, Manolis Linardakis, Vijayakumar C. Reddy, Odd Brørs, M. El Messal, Frosso Bervanaki, J. Alfredo Martínez, Y. Bamou
Publikováno v:
Annals of Nutrition and Metabolism. 49:204-204
Autor:
Haruo Isomura, Hiroshi Izumi, Yoshiaki Deyama, Wataru Sakamoto, Akihisa Kato, Katsutoshi Fujie, Jun Nishihira
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. (1):12-16
It has been pointed out that very high plasma levels of homocysteine are characteristic of homocystinuria, a rare autosomal recessive disease accompanied by the early onset of generalized osteoporosis. However, it is unclear by which mechanism hyperh