Zobrazeno 1 - 10
of 176
pro vyhledávání: '"Haruo Hanawa"'
Autor:
Kaori Sekine, Akira T. Kawaguchi, Masaki Miyazawa, Haruo Hanawa, Shinichi Matsuda, Tetsuro Tamaki, Takayuki Asahara, Haruchika Masuda
Publikováno v:
Biology, Vol 11, Iss 1, p 106 (2022)
Fulminant myocarditis causes impaired cardiac function, leading to poor prognosis and heart failure. Cell sheet engineering is an effective therapeutic option for improving cardiac function. Naïve blood mononuclear cells (MNCs) have been previously
Externí odkaz:
https://doaj.org/article/26041e16caf14e47860c42f34c96a5e4
Autor:
Keiji Okuda, Hai Ying Fu, Takashi Matsuzaki, Ryo Araki, Shota Tsuchida, Punniyakoti V Thanikachalam, Tatsuya Fukuta, Tomohiro Asai, Masaki Yamato, Shoji Sanada, Hiroshi Asanuma, Yoshihiro Asano, Masanori Asakura, Haruo Hanawa, Hiroyuki Hao, Naoto Oku, Seiji Takashima, Masafumi Kitakaze, Yasushi Sakata, Tetsuo Minamino
Publikováno v:
PLoS ONE, Vol 11, Iss 8, p e0160944 (2016)
Immunosuppressive agents are used for the treatment of immune-mediated myocarditis; however, the need to develop a more effective therapeutic approach remains. Nano-sized liposomes may accumulate in and selectively deliver drugs to an inflammatory le
Externí odkaz:
https://doaj.org/article/b6f03b9b98d0466baa5ef429389f3cb6
Publikováno v:
Journal of Clinical Medicine. 12:2813
(1) Background: Extracorporeal circulation (ECC) is indispensable for cardiac surgery. Despite the fact that ECC causes non-physiological damage to blood components, its pathophysiology has not been fully elucidated. In our previous study, we constru
Autor:
Takeshi Kashimura, Ippei Shimizu, Takayuki Wakasugi, Shuang Jiao, Kazuyuki Ozaki, Haruo Hanawa, Tohru Minamino, Y Hsiao, Yohko Yoshida, Tohru Watanabe
Publikováno v:
European Heart Journal. 41
Background/Introduction Mitochondria are dynamic regulators of cellular metabolism and homeostasis. The dysfunction of mitochondria has long been considered a major contributor to aging and age-related diseases. The prognosis of severe heart failure
Autor:
Tohru Watanabe, Y Hsiao, Ippei Shimizu, Tohru Minamino, Shuang Jiao, Haruo Hanawa, Yohko Yoshida, Takeshi Kashimura, Kazuyuki Ozaki, Takayuki Wakasugi
Publikováno v:
Circulation Research. 127
Background/Introduction: Mitochondria are dynamic regulators of cellular metabolism and homeostasis. The dysfunction of mitochondria has long been considered a major contributor to aging and age-related diseases. The prognosis of severe heart failure
Autor:
Tohru Watanabe, Kaori Yoshida, Shuang Jiao, Tomoyasu Suzuki, Hiroaki Obata, Haruo Hanawa, Yukako Ohno, Komei Tanaka, Yuka Hayashi, Takeshi Kashimura, Tohru Minamino
Publikováno v:
The Tohoku Journal of Experimental Medicine. 235:69-79
Hepcidin is a key regulator of mammalian iron metabolism and mainly produced by the liver. Hepcidin excess causes iron deficiency and anemia by inhibiting iron absorption from the intestine and iron release from macrophage stores. Anemia is frequentl
Mutation of the BMPR2 gene is the most common genetic cause of pulmonary arterial hypertension (PAH). Although there have been some reports of BMPR2 mutation carriers among PAH patients with congenital heart disease, there have been few reports of th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10ee4cada4228f6120c9ec26f795e3fb
https://europepmc.org/articles/PMC6149631/
https://europepmc.org/articles/PMC6149631/
Autor:
Shuang Jiao, Tomoyasu Suzuki, Kaori Yoshida, Tohru Minamino, Hiroaki Obata, Yuka Hayashi, Yukako Ohno, Haruo Hanawa, Takeshi Kashimura
Publikováno v:
Journal of Cardiac Failure. 20:268-277
Background Anemia and relative iron deficiency (RID) are prevalent in patients with heart failure (HF). The etiology of anemia and RID in HF patients is unclear. Hepcidin expression may be closely related to anemia and RID in HF patients. Although he
Publikováno v:
Clinical and Experimental Medicine. 14:397-408
Interleukin-18 (IL-18) is a powerful and important cytokine in myocarditis. IL-18-binding protein (IL-18BP), a naturally occurring antagonist of IL-18, is presumed to play a vital regulatory function in IL-18-mediated immune responses. The purpose of
Autor:
Tohru Minamino, Hiroaki Obata, Yuka Hayashi, Satoru Hirono, Takeshi Kashimura, Haruo Hanawa, Masahiro Ito, Makoto Kodama, Tohru Watanabe, Yukako Ohno, Komei Tanaka
Publikováno v:
Pacing and Clinical Electrophysiology. 37:197-206
Background Mechanical alternans (MA) and electrical alternans (EA) are predictors of cardiac events. Experimental studies have suggested that refractoriness of calcium cycling underlies these cardiac alternans. However, refractoriness of left ventric