Zobrazeno 1 - 10
of 303
pro vyhledávání: '"Haruo, Ogawa"'
Autor:
Takashi Murayama, Yuya Otori, Nagomi Kurebayashi, Toshiko Yamazawa, Hideto Oyamada, Takashi Sakurai, Haruo Ogawa
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-11 (2024)
Abstract The type 1 ryanodine receptor (RyR1) is a Ca2+ release channel in the sarcoplasmic reticulum that is essential for skeletal muscle contraction. RyR1 forms a channel with six transmembrane segments, in which S5 is the fifth segment and is tho
Externí odkaz:
https://doaj.org/article/99723d9c62544795905c3d32596cbeea
Autor:
Takuya Kobayashi, Akihisa Tsutsumi, Nagomi Kurebayashi, Kei Saito, Masami Kodama, Takashi Sakurai, Masahide Kikkawa, Takashi Murayama, Haruo Ogawa
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
Ryanodine receptor 2 (RyR2) is a Ca2+ release channel essential for cardiac excitation-contraction coupling. Here, the authors use structural and functional analysis to reveal RyR2 gating mechanism and its alterations by pathogenic mutations.
Externí odkaz:
https://doaj.org/article/6fcd432efb114ceaa2b312afe8315510
Autor:
Misato Ueda, Yasuki Hirayama, Haruo Ogawa, Tadashi Nomura, Hiroto Terashi, Shunsuke Sakakibara
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 13, p 10850 (2023)
This study aimed to elucidate the vasodilatory effects and cytotoxicity of various vasodilators used as antispasmodic agents during microsurgical anastomosis. Rat smooth muscle cells (RSMCs) and human coronary artery endothelial cells (HCAECs) were u
Externí odkaz:
https://doaj.org/article/7abf92b4a0954f7e8d02b7e4bf3a889f
Autor:
Yui Kuroda, Miki Nonaka, Yuji Kamikubo, Haruo Ogawa, Takashi Murayama, Nagomi Kurebayashi, Hakushun Sakairi, Kanako Miyano, Akane Komatsu, Tetsushi Dodo, Kyoko Nakano-Ito, Keisuke Yamaguchi, Takashi Sakurai, Masako Iseki, Masakazu Hayashida, Yasuhito Uezono
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 141, Iss , Pp 111800- (2021)
Background: The misuse of opioids has led to an epidemic in recent times. The endothelin A receptor (ETAR) has recently attracted attention as a novel therapeutic target to enhance opioid analgesia. We hypothesized that endothelin A receptors may aff
Externí odkaz:
https://doaj.org/article/9d6ee8e217b147f59416574fb884b2ce
Publikováno v:
Journal of Reconstructive Microsurgery Open, Vol 06, Iss 02, Pp e63-e69 (2021)
Background Necrotizing fasciitis is a well-known disease that causes extensive tissue infection and requires radical debridement of the infected tissue. It can occur in all parts of the body, but there are few reports of necrotizing fasciitis in the
Externí odkaz:
https://doaj.org/article/51f9cf70b6f4436aa8cbdf38b352349b
Autor:
Sakakibara, Misato Ueda, Yasuki Hirayama, Haruo Ogawa, Tadashi Nomura, Hiroto Terashi, Shunsuke
Publikováno v:
International Journal of Molecular Sciences; Volume 24; Issue 13; Pages: 10850
This study aimed to elucidate the vasodilatory effects and cytotoxicity of various vasodilators used as antispasmodic agents during microsurgical anastomosis. Rat smooth muscle cells (RSMCs) and human coronary artery endothelial cells (HCAECs) were u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=multidiscipl::fa82e9c48c14675b071d5ca43e4d5e34
Publikováno v:
Journal of Reconstructive Microsurgery Open, Vol 06, Iss 02, Pp e63-e69 (2021)
Background Necrotizing fasciitis is a well-known disease that causes extensive tissue infection and requires radical debridement of the infected tissue. It can occur in all parts of the body, but there are few reports of necrotizing fasciitis in the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40e440ab5a47bcf933bb751ccf23be50
https://doi.org/10.1055/s-0041-1736422
https://doi.org/10.1055/s-0041-1736422
Autor:
Hiroki Takai, Koji Masuda, Tomohiro Sato, Yuriko Sakaguchi, Takeo Suzuki, Tsutomu Suzuki, Ryo Koyama-Nasu, Yukiko Nasu-Nishimura, Yuki Katou, Haruo Ogawa, Yasuyuki Morishita, Hiroko Kozuka-Hata, Masaaki Oyama, Tomoki Todo, Yasushi Ino, Akitake Mukasa, Nobuhito Saito, Chikashi Toyoshima, Katsuhiko Shirahige, Tetsu Akiyama
Publikováno v:
Cell Reports, Vol 9, Iss 1, Pp 48-60 (2014)
Summary: The development of cancer is driven not only by genetic mutations but also by epigenetic alterations. Here, we show that TET1-mediated production of 5-hydroxymethylcytosine (5hmC) is required for the tumorigenicity of glioblastoma cells. Fur
Externí odkaz:
https://doaj.org/article/6e167373836c4249903547f389fae70e
Autor:
Yoshiki Inoue, Tomohiro Yamaguchi, Tetsuo Otsuka, Yuto Utsunomiya, Dongqing Pan, Haruo Ogawa, Hiroaki Kato
Publikováno v:
Protein Sci
ABCB1, also known as P‐glycoprotein, is an essential component of many physiological barriers and extrudes a variety of hydrophobic chemicals out of the cell. Structures of ABCB1 provided insights into the structural changes that occur upon ATP bin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::122c71630750986a5c62eaf2edda7894
https://doi.org/10.1002/pro.4331
https://doi.org/10.1002/pro.4331
Autor:
Haruo, Ogawa, Shinya, Tahara
Publikováno v:
Cureus.
Background The deep inferior epigastric perforator (DIEP) flap has been widely used in breast reconstruction. During surgery, many surgeons use closed suction drainage for both the donor site and the reconstructed breast. However, the criteria for dr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4583ef8750b7b0b642fed24dd126f99c
https://doi.org/10.7759/cureus.23665
https://doi.org/10.7759/cureus.23665