Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Harunori Honjoh"'
Autor:
Harunori Honjoh, Michihiro Tanikawa, Osamu Wada-Hiraike, Katsutoshi Oda, Hirofumi Inaba, Asako Kukita, Yoshiko Kawata, Misako Kusakabe, Saki Tsuchimochi, Ayumi Taguchi, Yuichiro Miyamoto, Kenbun Sone, Tetsushi Tsuruga, Mayuyo Mori-Uchino, Yoko Matsumoto, Yutaka Osuga
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-12 (2022)
Abstract Homologous recombination (HR) is a major repair pathway of DNA double-strand breaks and is closely related to carcinogenesis. HR deficiency has been established as a therapeutic target. The aim of this study was to elucidate the functions of
Externí odkaz:
https://doaj.org/article/70d1c957390a4af6ab20a679cbdd5d2b
Autor:
Machiko Kojima, Kenbun Sone, Katsutoshi Oda, Ryuji Hamamoto, Syuzo Kaneko, Shinya Oki, Asako Kukita, Hidenori Machino, Harunori Honjoh, Yoshiko Kawata, Tomoko Kashiyama, Kayo Asada, Michihiro Tanikawa, Mayuyo Mori-Uchino, Tetsushi Tsuruga, Kazunori Nagasaka, Yoko Matsumoto, Osamu Wada-Hiraike, Yutaka Osuga, Tomoyuki Fujii
Publikováno v:
BMC Cancer, Vol 19, Iss 1, Pp 1-9 (2019)
Abstract Background Wolf-Hirschhorn syndrome candidate gene-1 (WHSC1), a histone methyltransferase, has been found to be upregulated and its expression to be correlated with expression of enhancer of zeste homolog 2 (EZH2) in several cancers. In this
Externí odkaz:
https://doaj.org/article/192dd964004d4d0fbf3bbb6867880bf4
Autor:
Miku Wada, Asako Kukita, Kenbun Sone, Ryuji Hamamoto, Syuzo Kaneko, Masaaki Komatsu, Yu Takahashi, Futaba Inoue, Machiko Kojima, Harunori Honjoh, Ayumi Taguchi, Tomoko Kashiyama, Yuichiro Miyamoto, Michihiro Tanikawa, Tetsushi Tsuruga, Mayuyo Mori-Uchino, Osamu Wada-Hiraike, Yutaka Osuga, Tomoyuki Fujii
Publikováno v:
Biomolecules, Vol 10, Iss 12, p 1686 (2020)
The histone methyltransferase SETD8, which methylates the lysine 20 of histone H4 (H4K20), is reportedly involved in human carcinogenesis along with nonhistone proteins such as p53. However, its expression profiles and functions in the context of hig
Externí odkaz:
https://doaj.org/article/6a8f15775f7e49daa6197b4060d26c48
Autor:
Katsuhiko Nara, Ayumi Taguchi, Takehito Yamamoto, Konan Hara, Yuri Tojima, Harunori Honjoh, Akira Nishijima, Satoko Eguchi, Yuichiro Miyamoto, Kenbun Sone, Mayuyo Mori, Tappei Takada, Yutaka Osuga
Background: Single-agent chemotherapy with or without bevacizumab (Bev) is a standard therapy for platinum-resistant ovarian cancer (PR-OC). However, there is a lack of literature on chemotherapy agent selection in heterogenous PR-OC. Therefore, we a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f4d4a2bf4c245de199a7c6f96f6fe873
https://doi.org/10.21203/rs.3.rs-2759326/v1
https://doi.org/10.21203/rs.3.rs-2759326/v1
Autor:
Futaba, Inoue, Kenbun, Sone, Yusuke, Toyohara, Saki, Tanimoto, Yu, Takahashi, Misako, Kusakabe, Asako, Kukita, Harunori, Honjoh, Akira, Nishijima, Ayumi, Taguchi, Yuichiro, Miyamoto, Michihiro, Tanikawa, Takayuki, Iriyama, Mayuyo-Mori, Uchino, Tetsushi, Tsuruga, Osamu, Wada-Hiraike, Katsutoshi, Oda, Yutaka, Osuga
Publikováno v:
Biochemical and Biophysical Research Communications. 601:123-128
Histone modification is the key epigenetic mechanism that regulates gene expression. Coactivator-associated arginine methyltransferase 1 (CARM1) is an arginine methyltransferase that catalyzes dimethylation of histone H3 (H3R17) at arginine 17. Latel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a585cfce9aa966bdba006f6960eb8381
https://doi.org/10.1016/j.bbrc.2022.02.086
https://doi.org/10.1016/j.bbrc.2022.02.086
Autor:
Satoshi Baba, Toshio Igarashi, Katsuyuki Adachi, Shan-Guang Liang, Kensuke Tomio, Takahiro Koso, Harunori Honjoh, Yasuaki Nakamura
Publikováno v:
JAPANESE JOURNAL OF GYNECOLOGIC AND OBSTETRIC ENDOSCOPY. 37:199-205
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::794d22d5f83c4dc18a9372dead0776e7
https://doi.org/10.5180/jsgoe.37.1_199
https://doi.org/10.5180/jsgoe.37.1_199
Autor:
Kenbun Sone, Eri Suzuki, Ayumi Taguchi, Harunori Honjoh, Akira Nishijima, Satoko Eguchi, Yuichiro Miyamoto, Takayuki Iriyama, Mayuyo Mori, Yutaka Osuga
Publikováno v:
Journal of Clinical Medicine; Volume 11; Issue 21; Pages: 6527
Positive peritoneal cytology is a poor prognostic factor in patients with advanced endometrial cancer. Suspicious positive peritoneal cytology (class III) is commonly encountered in clinical practice. However, no standard treatment protocol exists fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d3b68b4e9244868b2761d82c960f829
https://doi.org/10.3390/jcm11216527
https://doi.org/10.3390/jcm11216527
Autor:
Katsutoshi Oda, Shinya Oki, Yutaka Osuga, Akira Kawata, Tomoyuki Fujii, Kazunori Nagasaka, Tetsushi Tsuruga, Ryuji Hamamoto, Yuichiro Miyamoto, Ayumi Taguchi, Syuzo Kaneko, Yoshiko Kawata, Machiko Kojima, Masakazu Sato, Harunori Honjoh, Tomoko Kashiyama, Osamu Hiraike, Kenbun Sone, Asako Kukita, Michihiro Tanikawa
Publikováno v:
Oncology Letters
Previous studies have suggested that histone methylation can modulate carcinogenesis and cancer progression. For instance, the histone methyltransferase SET and MYND domain containing 2 (SMYD2) is overexpressed in several types of cancer tissue. The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48f473614cd192fe98964b4ce79642fd
http://europepmc.org/articles/PMC7471656
http://europepmc.org/articles/PMC7471656
Autor:
Wataru Isono, Hiromi Terao, Tetsuya Hirata, Nana Akino, Harunori Honjoh, Kaori Koga, Tomoyuki Fujii, Kei Kawana, Miyuki Harada, Katsutoshi Oda, Yutaka Osuga, Houju Fu, Michihiro Tanikawa, Mana Hirano, Yasushi Hirota, Yuichiro Miyamoto, Osamu Wada-Hiraike
Publikováno v:
Molecular and Cellular Endocrinology. 470:96-104
Nuclear factor-E2-related factor 2 (Nrf2)/Kelch-like ECH-associated protein 1 (Keap1)-antioxidant response element (ARE) signaling pathway is one of the most important defense mechanisms against oxidative stress (OS). It is well documented that equil
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::068dc3b0935e14af2dc68b88089877d2
https://doi.org/10.1016/j.mce.2017.10.002
https://doi.org/10.1016/j.mce.2017.10.002
Autor:
Shinya Oki, Katsutoshi Oda, Harunori Honjoh, Asako Kukita, Tomoyuki Fujii, Ryuji Hamamoto, Tomoko Kashiyama, Mayuyo Mori-Uchino, Kayo Asada, Yoshiko Kawata, Machiko Kojima, Kenbun Sone, Syuzo Kaneko, Yutaka Osuga, Kazunori Nagasaka, Michihiro Tanikawa, Osamu Wada-Hiraike, Tetsushi Tsuruga, Hidenori Machino, Yoko Matsumoto
Publikováno v:
BMC Cancer
BMC Cancer, Vol 19, Iss 1, Pp 1-9 (2019)
BMC Cancer, Vol 19, Iss 1, Pp 1-9 (2019)
Background Wolf-Hirschhorn syndrome candidate gene-1 (WHSC1), a histone methyltransferase, has been found to be upregulated and its expression to be correlated with expression of enhancer of zeste homolog 2 (EZH2) in several cancers. In this study, w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4aa9b173db57360e6efcae5ea9ed54d8
http://europepmc.org/articles/PMC6521555
http://europepmc.org/articles/PMC6521555