Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Haruna Yamashiro"'
Autor:
Mayu Negishi, Hitoshi Ohtani, Mikiko C. Siomi, Tatsuki Kinoshita, Hirotsugu Ishizu, Haruna Yamashiro
Publikováno v:
EMBO Rep
Piwi and piRNA form the piRNA‐induced silencing complex (piRISC) to repress transposons. In the current model, Armitage (Armi) brings the Piwi–piRISC precursor (pre‐piRISC) to mitochondria, where Zucchini‐dependent piRISC maturation occurs. H
Autor:
Asuka Ogai, Haruhiko Siomi, Mikiko C. Siomi, Soichiro Yamanaka, Kazumichi M. Nishida, Lumi Negishi, Ryu Yashiro, Kaede Fujii, Haruna Yamashiro, Yukiko Murota
Publikováno v:
Cell reports. 23(12)
In Drosophila ovarian somatic cells (OSCs), Piwi represses transposons transcriptionally to maintain genome integrity. Piwi nuclear localization requires the N terminus and PIWI-interacting RNA (piRNA) loading of Piwi. However, the underlying mechani
Autor:
Mikiko C. Siomi, Haruna Yamashiro
Publikováno v:
Chemical reviews. 118(8)
PIWI-interacting RNAs (piRNAs) are germline-enriched small RNAs that control transposons to maintain genome integrity. To achieve this, upon being processed from piRNA precursors, most of which are transcripts of intergenic piRNA clusters, piRNAs bin