Zobrazeno 1 - 10
of 627
pro vyhledávání: '"Harun N"'
Autor:
Feng Li, Tsz Y. Lo, Leann Miles, Qin Wang, Harun N. Noristani, Dan Li, Jingwen Niu, Shannon Trombley, Jessica I. Goldshteyn, Chuxi Wang, Shuchao Wang, Jingyun Qiu, Katarzyna Pogoda, Kalpana Mandal, Megan Brewster, Panteleimon Rompolas, Ye He, Paul A. Janmey, Gareth M. Thomas, Shuxin Li, Yuanquan Song
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-20 (2021)
The Atr-Check1 pathway is involved in cell cycle and the DNA damage response. Here, the authors show that the Atr-Check1 pathway can inhibit axon regeneration in response to Piezo-mediated mechanosensation, affecting functional recovery.
Externí odkaz:
https://doaj.org/article/005c24fb0ae4423db9855a4fda43b7ac
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 15 (2022)
Primary sensory axons in adult mammals fail to regenerate after spinal cord injury (SCI), in part due to insufficient intrinsic growth potential. Robustly boosting their growth potential continues to be a challenge. Previously, we showed that constit
Externí odkaz:
https://doaj.org/article/b098ec788d1f4975a2e8d24517053aa0
Autor:
Jamie M. Caldwell, A. Desiree LaBeaud, Eric F. Lambin, Anna M. Stewart-Ibarra, Bryson A. Ndenga, Francis M. Mutuku, Amy R. Krystosik, Efraín Beltrán Ayala, Assaf Anyamba, Mercy J. Borbor-Cordova, Richard Damoah, Elysse N. Grossi-Soyster, Froilán Heras Heras, Harun N. Ngugi, Sadie J. Ryan, Melisa M. Shah, Rachel Sippy, Erin A. Mordecai
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
The effects of climate on vector-borne disease systems are highly context-dependent. Here, the authors incorporate laboratory-measured physiological traits of the mosquito Aedes aegypti into climate-driven mechanistic models to predict number, timing
Externí odkaz:
https://doaj.org/article/7e94089f5d4541288b742dd8e9360e7a
Autor:
Harun N. Ngugi, Sindiso Nyathi, Amy Krystosik, Bryson Ndenga, Joel O. Mbakaya, Peter Aswani, Peter S. Musunzaji, Lucy W. Irungu, Donal Bisanzio, Uriel Kitron, A. Desiree LaBeaud, Francis Mutuku
Publikováno v:
Parasites & Vectors, Vol 13, Iss 1, Pp 1-14 (2020)
Abstract Background Aedes aegypti is an efficient vector of several arboviruses of public health importance, including Zika and dengue. Currently vector management is the only available avenue for disease control. Development of efficient vector cont
Externí odkaz:
https://doaj.org/article/ab4d7f5f1efa4666a65f767a57a8e686
Autor:
Hussein Ghazale, Chantal Ripoll, Nicolas Leventoux, Laurent Jacob, Safa Azar, Daria Mamaeva, Yael Glasson, Charles-Felix Calvo, Jean-Leon Thomas, Sarah Meneceur, Yvan Lallemand, Valérie Rigau, Florence E. Perrin, Harun N. Noristani, Brenda Rocamonde, Emmanuelle Huillard, Luc Bauchet, Jean-Philippe Hugnot
Publikováno v:
Stem Cell Reports, Vol 12, Iss 5, Pp 1159-1177 (2019)
Summary: Anamniotes, rodents, and young humans maintain neural stem cells in the ependymal zone (EZ) around the central canal of the spinal cord, representing a possible endogenous source for repair in mammalian lesions. Cell diversity and genes spec
Externí odkaz:
https://doaj.org/article/705f9ae190674326953c60e1d157bba2
Publikováno v:
Brain Sciences, Vol 11, Iss 12, p 1643 (2021)
Microglia are major players in scar formation after an injury to the spinal cord. Microglia proliferation, differentiation, and survival are regulated by the colony-stimulating factor 1 (CSF1). Complete microglia elimination using CSF1 receptor (CSF1
Externí odkaz:
https://doaj.org/article/2a1ca4be16a0449fa1a891b1ad487562
Autor:
Claire J Heath, Elysse N Grossi-Soyster, Bryson A Ndenga, Francis M Mutuku, Malaya K Sahoo, Harun N Ngugi, Joel O Mbakaya, Peter Siema, Uriel Kitron, Nayer Zahiri, Jimmy Hortion, Jesse J Waggoner, Charles H King, Benjamin A Pinsky, A Desiree LaBeaud
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 14, Iss 6, p e0008362 (2020)
Arboviruses are among the most important emerging pathogens due to their increasing public health impact. In Kenya, continued population growth and associated urbanization are conducive to vector spread in both urban and rural environments, yet mecha
Externí odkaz:
https://doaj.org/article/b3266bf482014fd8860b562026735425
Autor:
Harun N. Ngugi, Francis M. Mutuku, Bryson A. Ndenga, Peter S. Musunzaji, Joel O. Mbakaya, Peter Aswani, Lucy W. Irungu, Dunstan Mukoko, John Vulule, Uriel Kitron, Angelle D. LaBeaud
Publikováno v:
Parasites & Vectors, Vol 10, Iss 1, Pp 1-12 (2017)
Abstract Background Aedes aegypti, the principal vector for dengue and other emerging arboviruses, breeds preferentially in various man-made and natural container habitats. In the absence of vaccine, epidemiological surveillance and vector control re
Externí odkaz:
https://doaj.org/article/2f2b54c84a424fd39f592b06c5cba229
Publikováno v:
Frontiers in Aging Neuroscience, Vol 9 (2017)
Over the last decade, microglia have been acknowledged to be key players in central nervous system (CNS) under both physiological and pathological conditions. They constantly survey the CNS environment and as immune cells, in pathological contexts, t
Externí odkaz:
https://doaj.org/article/377d9574fe7c4f10a1781563f29496e9
Publikováno v:
In Materials Today: Proceedings