Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Harun Budak"'
Publikováno v:
eLife, Vol 8 (2019)
Many physiological processes exhibit circadian rhythms driven by cellular clocks composed of interlinked activating and repressing elements. To investigate temporal regulation in this molecular oscillator, we combined mouse genetic approaches and ana
Externí odkaz:
https://doaj.org/article/9af7d511b4a9431e8571b37351139f01
Autor:
Melda Şişecioğlu, Harun Budak, Lars Geffers, Murat Çankaya, Mehmet Çiftci, Christina Thaller, Gregor Eichele, Ömer İrfan Küfrevioğlu, Hasan Özdemir
Publikováno v:
Journal of Lipid Research, Vol 56, Iss 8, Pp 1551-1559 (2015)
Cholesterol and its biosynthetic pathway intermediates and derivatives are required for many developmental processes including membrane biogenesis, transmembrane receptor signaling, steroid biogenesis, nuclear receptor activation, and posttranslation
Externí odkaz:
https://doaj.org/article/1a49bd1791be4705b4722c43dff57272
Publikováno v:
Journal of Applied Toxicology.
Publikováno v:
Cell Biochemistry and Biophysics.
Publikováno v:
Molecular Biology Reports. 48:7397-7404
Carbonic anhydrases (CAs) play an important role in maintaining pH balance by catalyzing the conversion of carbon dioxide to bicarbonate. Since this pH balance is critical to health, all organisms must develop mechanisms to control and regulate it. A
Autor:
Melike Karaman, Emine Toraman, Ekrem Sulukan, Alper Baran, İsmail Bolat, Serkan Yıldırım, Meryem Kankaynar, Atena Ghosigharehagaji, Harun Budak, Saltuk Buğrahan Ceyhun
Publikováno v:
Environmental toxicology and pharmacology. 97
Fluoride exposure through drinking water, foods, cosmetics, and drugs causes genotoxic effects, oxidative damage, and impaired cognitive abilities. In our study, the effects of fluoride on anxiety caused by the circadian clock and circadian clock cha
Publikováno v:
Journal of cellular biochemistryREFERENCES.
Tat-interactive protein 60 kDa (TIP60, also known as lysine acetyltransferase 5 [KAT5]) is a member of the MYST protein family with histone acetyltransferase activity. Recent studies have reported that TIP60 has multiple functions in many signal tran
Publikováno v:
Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine. 35(6)
Hepcidin (HAMP), an iron regulatory hormone synthesized by liver hepatocytes, works together with ferritin (FTH) and ferroportin (FPN) in regulating the storage, transport, and utilization of iron in the cell. Epigenetic mechanisms, especially acetyl
Publikováno v:
Chemico-Biological Interactions. 366:110128
This study aimed to evaluate the inflammatory response, hyperpolarization-activated cyclic nucleotide-gated 2 (HCN2), and voltage-gated potassium (Kv) 9.1 channel expression in rats with paclitaxel-induced neuropathic pain-like behavior.Sixteen male
Publikováno v:
Anti-Cancer Agents in Medicinal Chemistry. 18:1599-1605
Background:Thioredoxin reductase (E.C 1.6.4.5.; TrxR) is a widely distributed flavoprotein that catalyzes the NADPH-dependent reduction of thioredoxin (Trx) in many cellular events such as DNA synthesis, DNA repair, angiogenesis, antioxidative defens