Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Harumi Y. Mukai"'
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0119442 (2015)
Erythropoietin (Epo) and its receptor (EpoR) are required for the regulation of erythropoiesis. Epo binds to the EpoR homodimer on the surface of erythroid progenitors and erythroblasts, and positions the intracellular domains of the homodimer to be
Externí odkaz:
https://doaj.org/article/2ae5d37f7a0541bdbbfd6263a62d84e0
Publikováno v:
International Journal of Hematology. 99:726-736
Several clinical trials have demonstrated the effectiveness of bortezomib in combination with various anti-myeloma agents; however, no definitive information is available regarding drugs best suited for use in combination with bortezomib. Using isobo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::466e4899b7709cf496565df09e9f730f
https://doi.org/10.1007/s12185-014-1573-3
https://doi.org/10.1007/s12185-014-1573-3
Disruption of the Hbs1l-Myb Locus Causes Hereditary Persistence of Fetal Hemoglobin in a Mouse Model
Autor:
Masayuki Yamamoto, Harumi Y. Mukai, Hiromi Yamazaki, Hozumi Motohashi, Osamu Tanabe, Mikiko Suzuki, Lihong Shi, James Douglas Engel
Publikováno v:
Molecular and Cellular Biology. 33:1687-1695
The human β-globin locus is comprised of embryonic, fetal, and adult globin genes, each of which is expressed at distinct stages of pre- and postnatal development. Functional defects in globin proteins or expression results in mild to severe anemia,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c952e4eff446e2d695d198b4b68caac
https://doi.org/10.1128/mcb.01617-12
https://doi.org/10.1128/mcb.01617-12
Autor:
Atsushi Shinagawa, Yuichi Hasegawa, Masami Fujii, Harumi Y. Mukai, Masaharu Kamoshita, Tomofumi Kimura, Norio Chikatsu, Yuriko Monma, Takayoshi Ito, Shigeru Chiba, Daisuke Kudo, Norimichi Watanabe, Hiroshi Kojima, Kazumi Suzukawa, Yasushi Okoshi, Takuya Komeno, Seiichi Shimizu, Chikashi Yoshida, Mitsuo Hori
Publikováno v:
International Journal of Hematology. 93:618-623
The correlation between imatinib (IM) trough plasma concentration (Cmin) and clinical response was assessed in patients with chronic-phase chronic myeloid leukemia. The Cmin correlated with neither the achievement of complete cytogenetic response (97
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d859b12f0409c58c33c5c90c6888b6eb
https://doi.org/10.1007/s12185-011-0838-3
https://doi.org/10.1007/s12185-011-0838-3
Publikováno v:
Journal of Thrombosis and Haemostasis. 8:1088-1097
Summary. Background: The pro-apoptotic BH3-only protein Bim is recognized as a pivotal regulator of apoptosis induced by the depletion of cytokines. In the present study, we examined the role of Bim in megakaryopoiesis. Methods: Megakaryocyte (MK) pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bde2d9876ee9f32513d3f4b4f4ca42a
https://doi.org/10.1111/j.1538-7836.2010.03785.x
https://doi.org/10.1111/j.1538-7836.2010.03785.x
Autor:
Takayuki Machino, Yukitaka Katsura, Naoshi Obara, Yuichi Hasegawa, Hiroshi Kojima, Harumi Y. Mukai, Noriko Nemoto, Yasushi Okoshi, Toshiro Nagasawa, Yasushi Kawakami, Toru Nanmoku, Kazumi Suzukawa
Publikováno v:
Cancer Genetics and Cytogenetics. 178(1):85-88
application/pdf
The t(5;12)(q31not, vert, similar35;p12not, vert, similar13) is rare among cytogenetically categorized myeloid diseases. Here we describe a case of myelodysplastic syndrome (MDS) with basophilia followed by leukocytosis, basophil
The t(5;12)(q31not, vert, similar35;p12not, vert, similar13) is rare among cytogenetically categorized myeloid diseases. Here we describe a case of myelodysplastic syndrome (MDS) with basophilia followed by leukocytosis, basophil
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1fad522c6248e75a8f3971c3956746b2
https://tsukuba.repo.nii.ac.jp/records/15049
https://tsukuba.repo.nii.ac.jp/records/15049
Autor:
Osamu Ohneda, Masayuki Yamamoto, Harumi Y. Mukai, Masumi Nagano, Norio Suzuki, Hozumi Motohashi
Publikováno v:
Molecular and Cellular Biology. 26:7953-7965
The nuclear proto-oncogene c-myb plays crucial roles in the growth, survival, and differentiation of hematopoietic cells. We established three lines of erythropoietin receptor-transgenic mice and found that one of them exhibited anemia, thrombocythem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebbf83894ab9e55332d9012ceca676ab
https://doi.org/10.1128/mcb.00718-06
https://doi.org/10.1128/mcb.00718-06
Autor:
Kazumi Suzukawa, Yasuhiro Yoda, Toshiro Nagasawa, Yasushi Okoshi, Naoko Takei, Harumi Y. Mukai, Takayoshi Itoh
Publikováno v:
International Journal of Hematology. 83:247-251
Results of recent studies with animal models suggest that expression of MLL fusion proteins promotes acute leukemogenesis. However, the most potent MLL fusion proteins are not sufficient for the development of acute myeloid leukemia (AML). The clinic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c847f698f3c9be14ce9e0aa5de897c4
https://doi.org/10.1532/ijh97.05152
https://doi.org/10.1532/ijh97.05152
Autor:
Yoriko Yamashita, Toshiro Nagasawa, Shin Kaneko, Yuichi Hasegawa, Hiroshi Kojima, Harumi Y. Mukai, Tsunehiko Komatsu, Takuya Komeno, Atsushi Shinagawa, Yasuhiro Kawachi, Kazumi Suzukawa, Naoyoshi Mori, Masaharu Kamoshita, Toshitaka Kobayashi, Shoichi Mitsuhashi
Publikováno v:
Leukemia Research. 28:1287-1292
Clinicopathological features of 36 patients, male: 58.3%; median: 68 years, with "peripheral T-cell lymphoma, unspecified" diagnosed by the WHO criteria were reviewed. Majority (69.4%) had stage IV disease with frequent involvements into bone marrow,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2cfe2ca17ae086f78b99fb6c908a48e4
https://doi.org/10.1016/j.leukres.2004.04.016
https://doi.org/10.1016/j.leukres.2004.04.016
Autor:
Tatsuo Iijima, Yuichi Hasegawa, Chikashi Yoshida, Kazumi Suzukawa, Hiroshi Kojima, Masato Abei, Seiichi Shimizu, Yukitaka Katsura, Harumi Y. Mukai, Toshiro Nagasawa
Publikováno v:
European Journal of Haematology. 72:225-228
A 54-yr-old female having chronic neutrophilic leukemia (CNL) associated with severe liver injury is presented. Physical examination on admission showed severe jaundice, hepatosplenomegaly, massive ascites, and pretibial edema. Complete blood count s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c80da1c68deecc653ae0e4aecd6bbf72
https://doi.org/10.1046/j.0902-4441.2003.00203.x
https://doi.org/10.1046/j.0902-4441.2003.00203.x