Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Harumi Kitaura"'
Publikováno v:
Journal of Pharmacological Sciences, Vol 113, Iss 2, Pp 143-152 (2010)
We investigated the effects of various emetic agents: cisplatin, apomorphine, lithium chloride (LiCl), rolipram, sibutramine, and the β3-adrenoceptor (AR) agonist CL316243 on salivary amylase secretion in rats. We also determined the inhibitory effe
Externí odkaz:
https://doaj.org/article/95f1eda6a65e4e0bb89def468e6beede
Autor:
Hirohiko Ohtsuka, Kazuaki Takahashi, Harumi Kitaura, Hitoshi Kandori, Kenta Danbayashi, Tomoaki Higuchi, Fumihiro Jinno, Shin-ichiro Nitta, Kanae Mori, Atsushi Iwai, Keiko Nakai, Kosuke Saito, Yoshiro Saito
Publikováno v:
The Journal of toxicological sciences. 47(5)
According to ICH S3A QA focusing on microsampling, its application should be avoided in main study animals for test drugs that could exacerbate hematological parameters with frequent blood sampling. However, no study has reported the effects of micro
Autor:
Hideaki Yokoyama, Eiji Murata, Fumihiro Jinno, Harumi Kitaura, Atsushi Iwai, Yoshiro Saito, Kyotaka Muta, Norimichi Hattori, Kosuke Saito, Kanae Mori, Hirohiko Ohtsuka, Akio Kobayashi, Asuka Takumi, Keiko Nakai
Publikováno v:
The Journal of Toxicological Sciences. 45:319-325
Due to finalization of the ICH S3A Q&A focusing on microsampling, application of microsampling technique to regular non-clinical animal studies is expected for non-clinical safety assessment of pharmaceuticals. In Europe, microsampling from the tail