Zobrazeno 1 - 10
of 80
pro vyhledávání: '"Harumi Fukada"'
Publikováno v:
Appl Environ Microbiol
Chitin is a biopolymer of N-acetyl-d-glucosamine with β-1,4-bond and is the main component of arthropod exoskeletons and the cell walls of many fungi. Chitinase (EC 3.2.1.14) is an enzyme that hydrolyzes the β-1,4-bond in chitin and degrades chitin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48e5ce03a6353c7e1fa7ceab17c27ed6
https://doi.org/10.1128/aem.00652-22
https://doi.org/10.1128/aem.00652-22
Autor:
Masaaki Sawa, Takayoshi Kinoshita, Takashi Matsumoto, Akihito Yamano, Yuka Murakawa, Harumi Fukada
Publikováno v:
Biochemical and Biophysical Research Communications. 521:106-112
Mitogen-activated protein kinase kinase 4 (MAP2K4) plays a critical role in regulating the stress-activated protein kinase signaling cascade. A small angle X-ray scattering experiment, a powerful technique for analyzing a solution structure cleared f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb84949e37012d29d91fe06c4924c179
https://doi.org/10.1016/j.bbrc.2019.10.086
https://doi.org/10.1016/j.bbrc.2019.10.086
Autor:
Ana Luíza Gomide Fabiano, Júlia Harumi Fukada, Maria Júlia Matos De Oliveira, Cíntia Aparecida Meneguci
Publikováno v:
Medicina do Exercício e do Esporte: evidências científicas para uma abordagem multiprofissional-Volume 2 ISBN: 9786553603202
As neoplasias, que usualmente possuem como parte do tratamento as amputações, afetam especialmente a população jovem. Sendo assim, há uma ampla exigência por estratégias pré-cirúrgicas, cirúrgicas e pós-cirúrgicas bem elaboradas para apri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::41693821a351e6380dfb2bc5b98fedbf
https://doi.org/10.37885/230312481
https://doi.org/10.37885/230312481
Autor:
Takashi Matsumoto, Yuri Sogabe, Harumi Fukada, Masaaki Sawa, Takayoshi Kinoshita, Takuma Hashimoto
Publikováno v:
Biochemical and Biophysical Research Communications. 493:313-317
Mitogen-activated protein kinase kinase 7 (MAP2K7) regulates stress and inflammatory responses, and is an attractive drug discovery target for several diseases including arthritis and cardiac hypertrophy. Intracellular proteins such as MAP2K7 are pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8eda5ed7079b4dc161262868e2fddc57
https://doi.org/10.1016/j.bbrc.2017.09.025
https://doi.org/10.1016/j.bbrc.2017.09.025
Publikováno v:
Journal of Thermal Analysis and Calorimetry. 131:335-341
Structure folding dictates protein functions. Recent advances in structural analysis such as NMR and X-ray crystallography enabled to determine protein structures at high resolution, which helps understanding of protein folding and recognition mechan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2a8e235de3ce9ac0a8b0e5e3ba4aa42a
https://doi.org/10.1007/s10973-017-6524-9
https://doi.org/10.1007/s10973-017-6524-9
Publikováno v:
Molecular Immunology. 85:130-136
Immune response to T-cell-dependent antigens is highly dynamic; several B-cell clones responsible for antibody production appear alternately during immunization. It was previously shown that at least two-types of antibodies are secreted after immuniz
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea563dcaa29c59896ad5a36ff6c22ded
https://doi.org/10.1016/j.molimm.2017.02.010
https://doi.org/10.1016/j.molimm.2017.02.010
Autor:
Yusuke Tanaka, Satomi Inaba, Hiroshi Sekiguchi, Takachika Azuma, Yusui Sato, Takahiro Maruno, Masayuki Oda, Yuji C. Sasaki, Yuji Kobayashi, Harumi Fukada
Publikováno v:
International Journal of Biological Macromolecules. 91:151-157
Protein structure dynamics are critical for understanding structure-function relationships. An antibody can recognize its antigen, and can evolve toward the immunogen to increase binding strength, in a process referred to as affinity maturation. In t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::deccfbb9a45b5a6e2500794c082b5f62
https://doi.org/10.1016/j.ijbiomac.2016.05.074
https://doi.org/10.1016/j.ijbiomac.2016.05.074
Publikováno v:
Biochemistry. 55:724-732
Bacillus sp. TB-90 urate oxidase (BTUO) is one of the most thermostable homotetrameric enzymes. We previously reported [Hibi, T., et al. (2014) Biochemistry 53, 3879-3888] that specific binding of a sulfate anion induced thermostabilization of the en
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49dbf0b0ad7b0b0a2a333d74451cab8d
https://doi.org/10.1021/acs.biochem.5b01119
https://doi.org/10.1021/acs.biochem.5b01119
Publikováno v:
Journal of pharmaceutical sciences. 107(11)
We have here observed that the differential scanning calorimetry profiles and melting temperatures of a humanized antibody were unchanged over a 10-year span when stored at 4°C and at different pH values, even at pH 2.7. This is somewhat surprising,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87451163af5a8fbcd782e4f6d786f02c
https://pubmed.ncbi.nlm.nih.gov/30017886
https://pubmed.ncbi.nlm.nih.gov/30017886
Publikováno v:
Journal of Thermal Analysis and Calorimetry. 123:1763-1767
Protein folding thermodynamics can determine the contribution of protein fluctuation, which is difficult to detect but critical for protein function. We have analyzed the structural dynamic properties of the DNA-binding domain of a transcriptional ac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::429326578859b33d0219473cb0f5ee5c
https://doi.org/10.1007/s10973-015-4812-9
https://doi.org/10.1007/s10973-015-4812-9