Výsledky vyhledávání - "Harumi, Kumagai"

A Novel In Vitro Membrane Permeability Methodology Using Three-dimensional Caco-2 Tubules in a Microphysiological System Which Better Mimics In Vivo Physiological Conditions

Autor: Linda Gijzen, Kouichi Yoshinari, Niels Ouwerkerk, Kei Motonaga, Marleen Bokkers, Yuki Hagiwara, Remko van Vught, Harumi Kumagai, Tomokazu Tajiri, Rumaisha Annida, Yoshifumi Katakawa

Publikováno v: Journal of Pharmaceutical Sciences. 111:214-224

The aim of this study was to develop an in vitro drug permeability methodology which mimics the gastrointestinal environment more accurately than conventional 2D methodologies through a three-dimensional (3D) Caco-2 tubules using a microphysiological

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::536eaebc2e2e2421c39c2c797264f2bf
https://doi.org/10.1016/j.xphs.2021.11.016

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Effect of 4-[(5,6,7,8-Tetrahydro-5,5,8,8-Tetramethyl-2-Naphthalenyl)Carbamoyl]Benzoic Acid (Am80) on Alveolar Regeneration in Adiponectin Deficient-Mice Showing a Chronic Obstructive Pulmonary Disease–Like Pathophysiology

Autor: Mai Hirokawa, Tomomi Akita, Hitomi Sakai, Michiko Horiguchi, Isao Tachibana, Harumi Kumagai, Yoshito Takeda, Yuki Oiso, Norikazu Maeda, Chikamasa Yamashita, Chihiro Ozawa

Publikováno v: Journal of Pharmacology and Experimental Therapeutics. 361:501-505

Chronic obstructive pulmonary disease (COPD) is an intractable pulmonary disease that causes widespread and irreversible alveolar collapse. Although COPD occurs worldwide, only symptomatic therapy is currently available. Our objective is the developm

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef2afc60ec71d1324edb4b77b2e43245
https://doi.org/10.1124/jpet.117.240515

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Pulmonary administration of 1,25-dihydroxyvitamin D3 to the lungs induces alveolar regeneration in a mouse model of chronic obstructive pulmonary disease

Autor: Chikamasa Yamashita, Mai Hirokawa, Kaori Abe, Harumi Kumagai, Michiko Horiguchi

Publikováno v: Journal of Controlled Release. 233:191-197

Chronic obstructive pulmonary disease (COPD) is a progressive respiratory disease with several causes, including smoking, and no curative therapeutic agent is available, particularly for destructive alveolar lesions. In this study, we investigated th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::439bec04101068dc5f746cda3db10a01
https://doi.org/10.1016/j.jconrel.2016.05.006

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A contribuição da Biblioteca Virtual da FAPESP na disseminação e acesso equitativo às informações relacionadas à mudança climática e seus impactos globais

Autor: Morais, Thais Fernandes de, Hashimoto, Paula Harumi Kumagai, Krzyzanowski, Rosaly Favero

Publikováno v: Revista Brasileira de Biblioteconomia e Documentação; v. 13 (2017): CBBD 2017; 216-227
RBBD. Revista Brasileira de Biblioteconomia e Documentação
Federação Brasileira de Associações de Bibliotecários, Cientistas da Informação e Instituições (FEBAB)
instacron:FEBAB

Relata a experiência e o papel da Biblioteca Virtual da Fundação de Amparo à Pesquisa do Estado de São Paulo (BV-FAPESP) na disseminação dos projetos de pesquisas realizados com apoio da FAPESP e de seus resultados, relacionados ao tema Mudan�

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______3056::806fcdc4360d42e58c2a339a5938c4f6
https://rbbd.febab.org.br/rbbd/article/view/867

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The mechanism of solifenacin release from a pH-responsive ion-complex oral suspension in the fasted upper gastrointestinal lumen

Autor: Maria Vertzoni, Kei Motonaga, Niels Ouwerkerk, Christos Reppas, Yoshifumi Katakawa, Daisuke Murayama, Yosuke Yamamoto, Moe Haneda, Tomokazu Tajiri, Harumi Kumagai

Publikováno v: European Journal of Pharmaceutical Sciences. 142:105107

The main objective of this study was to investigate the mechanism of solifenacin release from a pH-responsive ion-complex oral resinate suspension under conditions simulating the environment in the upper gastrointestinal lumen. A secondary objective

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e96b1c0f5519696a6c0d79607e43ed5
https://doi.org/10.1016/j.ejps.2019.105107

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Preservação da memória institucional: relato de experiência da biblioteca virtual da fundação de amparo à pesquisa do Estado de São Paulo (BV-FAPESP)

Autor: Morais, Thais Fernandes de, Krzyzanowski, Rosaly Fávero, Pereira, Fabiana Andrade, Imperatriz, Inês Maria Morais, Calherani, Juliana, Hashimoto, Paula Harumi Kumagai

Publikováno v: Revista Brasileira de Biblioteconomia e Documentação; v. 12 (2016): N. Especial-III Integrar; 65-70
RBBD. Revista Brasileira de Biblioteconomia e Documentação
Federação Brasileira de Associações de Bibliotecários, Cientistas da Informação e Instituições (FEBAB)
instacron:FEBAB

Este trabalho tem como objetivo relatar a experiência e o papel da Biblioteca Virtual da Fundação de Amparo à Pesquisa do Estado de São Paulo (BV-FAPESP) na preservação da memória institucional da Fundação.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______3056::c6d5068587ed6c081d4ee365e2aded0b
https://rbbd.febab.org.br/rbbd/article/view/584

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Detection of tumor cells in blood using CD45 magnetic cell separation followed by nested mutant allele-specific amplification ofp53 and K-ras genes in patients with colorectal cancer

Autor: Harumi Kumagai, Akimitsu Ida, Junko Tamura, Koichi Sakagawa, Miki Adachi, Kazufumi Suda, Yasuo Baba, Toshiyuki Sekine, Kota Okinaga, Hisae Iinuma

Publikováno v: International Journal of Cancer. 89:337-344

A new method for detecting circulating tumor cells that is based on magnetic-activated cell separation (MACS) and nested mutant allele-specific amplification (nested MASA) was evaluated in patients with colorectal cancer using the p53 and K-ras genes

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16e9596eafbd213e484e85b55225c00d
https://doi.org/10.1002/1097-0215(20000720)89:4<337::aid-ijc4>3.0.co

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Histological evaluation of benign prostatic hyperplasia treated by long-term administration of chlormadinone acetate (CMA)

Autor: Harumi Kumagai, Koichi Sasaki, Masatoshi Moriyama, Masaoki Harada, Masahiko Hosaka, Kondo I, Mitsuru Nakahashi, Yuzo Kinoshita

Publikováno v: The Prostate. 25:147-155

Although the clinical effects of attempted nonsurgical treatment of benign prostatic hyperplasia have been well documented, detailed histological evaluation of the effects of treatment appears to be limited. The effect of long-term administration of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31cffdd1da54fc1fadbd558816dddb09
https://doi.org/10.1002/pros.2990250306

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Pharyngeal Blood Flow in Patients with Abnormal Sensation in the Throat

Autor: Takeshi Kubo, Harumi Kumagai, Toru Matsunaga, Takayuki Shiraishi

Publikováno v: Nihon Kikan Shokudoka Gakkai Kaiho. 42:457-461

We examined the blood flow in the pharyngeal mucous membrane of patients with abnormal sensation in the throat (AST) using a tissue spectrum analizer (TS-200, Sumitomo Elec.). Index Hemogrobin (IHb) was measured as an indicator of the blood flow by T

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::38002b05343aed14a58bbf66028043c0
https://doi.org/10.2468/jbes.42.457

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