Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Harukuni Tsumura"'
Autor:
Tatsuo Sakai, Toshiro Fujita, Masafumi Takahashi, Satoshi Kinugasa, Harukuni Tsumura, Akihiro Tojo, Yasunobu Hirata
Publikováno v:
Kidney International. 80:1328-1338
The mechanism of selective albuminuria in minimal change nephrotic syndrome, in which glomerular capillaries are diffusely covered by effaced podocyte foot processes with reduced slit diaphragms, is unknown. Podocyte injury is due, in part, to NADPH-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71ddb5d7b91deb64bb92ab3981c404e7
https://doi.org/10.1038/ki.2011.282
https://doi.org/10.1038/ki.2011.282
Various adhesion molecules impair microvascular leukocyte kinetics in ventilator-induced lung injury
Autor:
Shinji Sakamoto, Naoki Miyao, Kei Takeshita, Akitoshi Ishizaka, Hiroyasu Kudo, Harukuni Tsumura, Takuya Tamatani, Makoto Suematsu, Kazuhiro Yamaguchi, Kazumi Nishio, Rika Hiraoka, Yukio Suzuki, Makoto Ishii
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology. 290:L1059-L1068
Although the endothelial expression of various adhesion molecules substantially differs between pulmonary microvessels, their importance for neutrophil and lymphocyte sequestration in ventilator-induced lung injury (VILI) has not been systematically
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e398d8483e66fac51dc87be872ff5865
https://doi.org/10.1152/ajplung.00365.2005
https://doi.org/10.1152/ajplung.00365.2005
Autor:
Katsuhiko Naoki, Naoki Miyao, Kei Takeshita, H. Kudo, N. Sato, Yusuke Suzuki, Kazuhiro Yamaguchi, Harukuni Tsumura, K. Suzuki, Makoto Ishii
Publikováno v:
European Respiratory Journal. 20:43-51
The aim of the present study was to compare microvessel responses to hypercapnic and isocapnic acidosis in hyperoxia-injured lungs and to assess the role of constitutive and inducible forms of nitric oxide synthase (NOS) and cyclo-oxygenase (COX). Re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f903547600fe09c635b1596da784d41
https://doi.org/10.1183/09031936.02.00263502
https://doi.org/10.1183/09031936.02.00263502
Autor:
Kazumi Nishio, Harukuni Tsumura, Kei Takeshita, Naoki Miyao, Kazuhiro Yamaguchi, Makoto Suematsu, Hiroyasu Kudo, Yukio Suzuki, Koichi Suzuki, Hiroshi Serizawa, Nagato Sato, Katsuhiko Naoki
Publikováno v:
American Journal of Respiratory and Critical Care Medicine. 161:1681-1688
To assess the importance of endothelial intercellular adhesion molecule-1 (ICAM-1) in microvascular leukocyte kinetics in diseased lungs, we investigated the transitional changes in ICAM-1 expression, vascular diameter, and leukocyte behavior in rat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e086046d38173e975588cc36d93180db
https://doi.org/10.1164/ajrccm.161.5.9907104
https://doi.org/10.1164/ajrccm.161.5.9907104
Autor:
Nagato Sato, Kazuhiro Yamaguchi, Hiroyasu Kudo, Kazumi Nishio, Harukuni Tsumura, Koichi Suzuki, Katsuhiko Naoki, Kei Takeshita, Yukio Suzuki
Publikováno v:
The American journal of physiology. 277(1)
The issue of whether the acinar microvessel response to alveolar hypoxia and hypercapnia is impaired in injured lungs has not been vigorously addressed, despite the importance of knowing whether it is or not when treating patients with serious lung i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d045d5c7168d9e91825958748a406074
https://pubmed.ncbi.nlm.nih.gov/10409272
https://pubmed.ncbi.nlm.nih.gov/10409272
Autor:
Harukuni Tsumura, Kazuhiro Yamaguchi, Hiroyasu Kudo, Nagato Sato, Yukio Suzuki, Kazumi Nishio, Atsushi Miyata, Koichi Suzuki, Kei Takeshita, Takuya Aoki, Yuki Yamakawa, Katsuhiko Naoki
Publikováno v:
American journal of respiratory and critical care medicine. 158(2)
To assess the effects of exposure of the lung to hyperoxic conditions on reactivity of pulmonary microcirculation to hypoxic stimulation, we measured hypoxia-elicited overall pulmonary pressor changes (HPV) and microvascular diameter changes in intra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::830abcfb5331f795af6aa340436e6b8a
https://pubmed.ncbi.nlm.nih.gov/9700141
https://pubmed.ncbi.nlm.nih.gov/9700141
Autor:
Koichi Suzuki, Harukuni Tsumura, Kazumi Nishio, Hiroyasu Kudo, Takuya Aoki, Yukio Suzuki, Katsuhiko Naoki, Kei Takeshita, Nagato Sato, Atsushi Miyata, Kazuhiro Yamaguchi
Publikováno v:
Circulation research. 82(6)
Abstract —To elucidate the differential reactivity of pulmonary microvessels in the acini to hypoxia, excessive CO 2 , and increased H + , we investigated changes in the diameter of precapillary arterioles, postcapillary venules, and capillaries in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a883e0af455563a7d777f5389aacc37c
https://pubmed.ncbi.nlm.nih.gov/9546381
https://pubmed.ncbi.nlm.nih.gov/9546381
Autor:
Makoto Suematsu, Kazumi Nishio, Harukuni Tsumura, Kazuhiro Yamaguchi, Hiroyasu Kudo, Takuya Aoki, Yukio Suzuki, Katsuhiko Naoki, Koichi Suzuki, Hiroshi Serizawa, Atsushi Miyata, Shigeaki Moro-oka, Nagato Sato, Yuzuru Ishimura
Publikováno v:
American journal of respiratory and critical care medicine. 157(2)
To elucidate the differential role of various adhesion molecules in distorting leukocyte behavior in the microvasculature of hyperoxia-exposed rat lungs, we investigated fluorescein-labeled leukocyte and erythrocyte kinetics in isolated lungs taken f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e391ca8849c6039eeebaec16dd78e34
https://pubmed.ncbi.nlm.nih.gov/9476879
https://pubmed.ncbi.nlm.nih.gov/9476879
Autor:
Kazuhiro Yamaguchi, Harukuni Tsumura, Koichi Suzuki, Atsusi Miyata, Takuya Aoki, Katsuhiko Naoki, Yukio Suzuki, Kazumi Nishio, Hiroyasu Kudo, Nagato Sato
Publikováno v:
Oxygen Homeostasis and Its Dynamics ISBN: 9784431684787
This study was designed to examine how leukocyte traffic occurs in the pulmonary microcirculation under physiological shear rates. The leukocyte-endothelium interaction was visualized in perfused rat lungs using an intravital highspeed confocal laser
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cd22a3894d2b3422bab951e498ef6ff1
https://doi.org/10.1007/978-4-431-68476-3_78
https://doi.org/10.1007/978-4-431-68476-3_78
Autor:
Hiroshi Serizawa, Makoto Suematsu, Yukio Suzuki, Kouichi Suzuki, Takuya Aoki, Yuzuru Ishimura, Kazumi Nishio, Harukuni Tsumura, Yutaka Iigou, Atsusi Miyata, Kazuhiro Yamaguchi
Publikováno v:
The American journal of physiology. 273(5)
This study aimed to examine the behavior of stimulated leukocytes in the pulmonary microcirculation. The leukocyte-endothelium interaction was visualized under physiological shear rates in perfused rat lungs using high-speed confocal laser video micr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3cbbda03798d5decb583df6d9a74cdba
https://pubmed.ncbi.nlm.nih.gov/9374773
https://pubmed.ncbi.nlm.nih.gov/9374773