Výsledky vyhledávání - "Haruki Yamada"

Akademický článek

Cepharanthine synergistically promotes methylprednisolone pharmacodynamics against human peripheral blood mononuclear cells possibly via regulation of P-glycoprotein/glucocorticoid receptor translocation

Autor: Wencheng Xu, Shuhe Chen, Xiaoqin Wang, Jinwen Min, Sachiko Tanaka, Kenji Onda, Kentaro Sugiyama, Haruki Yamada, Toshihiko Hirano

Publikováno v: BMC Complementary Medicine and Therapies, Vol 24, Iss 1, Pp 1-12 (2024)

Abstract Background Cepharanthin® alone or in combination with glucocorticoid (GC) has been used to treat chronic immune thrombocytopenia (ITP) since the 1990s. Cepharanthine (CEP) is one of the main active components of Cepharanthin®. The purpose

Externí odkaz: https://doaj.org/article/714da0c0f0b54aeda986ca505bb97532

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Akademický článek

Pyogenic psoas abscess on the dorsal side, and bacterial meningitis and spinal epidural abscess on the ventral side, both of which were induced by spontaneous discitis in a patient with diabetes mellitus: A case report

Autor: Megumi Horiya, Takatoshi Anno, Mayuko Kawada, Haruki Yamada, Kaiou Takahashi, Haruka Takenouchi, Hideyuki Iwamoto, Fumiko Kawasaki, Katsumi Kurokawa, Hideaki Kaneto, Kohei Kaku, Koichi Tomoda

Publikováno v: Journal of Diabetes Investigation, Vol 12, Iss 7, Pp 1301-1305 (2021)

Abstract Type 2 diabetes mellitus patients are immunocompromised, particularly under poorly controlled conditions, and thereby they could develop rare inflammatory diseases, such as spontaneous discitis, pyogenic psoas abscess, spinal epidural absces

Externí odkaz: https://doaj.org/article/86e7c0b8359141b897320e8453181fc9

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Preparation of Tenuifolin from Polygala senega L. Root Using a Hydrolytic Continuous Flow System under High-Temperature, High-Pressure Conditions

Autor: Takayori Tojima, Masaki Yokoyama, Tatsuki Kitazoe, Takayuki Nagai, Takashi Nishino, Naruki Konishi, Eisuke Kaji, Tatsuya Shirahata, Hiroaki Kiyohara, Rintaro Miyaishi, Masaya Saito, Yoshinori Kobayashi, Yuki Taneoka, Shuhei Hidaka, Tatsuya Katsumi, Nozomu Hirata, Shunsuke Nakamori, Haruki Yamada

Publikováno v: The Journal of Organic Chemistry. 86:16268-16277

An improved process for preparing tenuifolin (presenegenin 3-β-d-glucopyranoside) from the root of Polygala senega L. was developed. A crude saponin mixture extracted from P. senega was subjected to hydrolysis, and the reactivity of compounds in the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6f19d3263977dfd135ed05842ad47dbb
https://doi.org/10.1021/acs.joc.1c01125

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Autor: Mayuko Kawada, Fumiko Kawasaki, Takatoshi Anno, Megumi Horiya, Haruki Yamada, Hideaki Kaneto, Katsumi Kurokawa, Kaiou Takahashi, Koichi Tomoda, Hideyuki Iwamoto, Haruka Takenouchi, Kohei Kaku

Publikováno v: Journal of Diabetes Investigation
Journal of Diabetes Investigation, Vol 12, Iss 7, Pp 1301-1305 (2021)

Type 2 diabetes mellitus patients are immunocompromised, particularly under poorly controlled conditions, and thereby they could develop rare inflammatory diseases, such as spontaneous discitis, pyogenic psoas abscess, spinal epidural abscess and bac

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::007c8f2f0e23a17dae5be650d4bf9c7c
http://europepmc.org/articles/PMC8264412

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Absolute configuration of tetrandrine and isotetrandrine influences their anti-proliferation effects in human T cells via different regulation of NF-κB

Autor: Yoshikazu Hara, Seiichi Hayashi, Hiroto Matsuda, Yoshiaki Fujii, Sachiko Tanaka, Kentaro Sugiyama, Junichi Kusano, Haruki Yamada, Ryusei Yamamoto, Toshihiko Hirano, Wencheng Xu, Shuhe Chen

Publikováno v: Zeitschrift für Naturforschung C. 76:21-25

Natural compound tetrandrine was reported to inhibit the proliferation of T cells by inhibiting activation of NF-κB. Chemically, isotetrandrine differs from tetrandrine only in the stereochemistry at the chiral centers. The present study aimed to co

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d914269f60e29ea48b3d12c1820aede
https://doi.org/10.1515/znc-2020-0064

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NF-κB regulation by bisbenzylisoquinoline alkaloids in human T cells: a structure–activity relationship study

Autor: Yoshiaki Fujii, Wencheng Xu, Sachiko Tanaka, Seiichi Hayashi, Xiaoqin Wang, Ryusei Yamamoto, Yoshikazu Hara, Kentaro Sugiyama, Haruki Yamada, Hiroto Matsuda, Toshihiko Hirano, Junichi Kusano, Shuhe Chen

Publikováno v: Medicinal Chemistry Research. 29:2123-2129

Suppressive potencies of tetrandrine, isotetrandrine, fangchinoline, berbamine, dauricine, cepharanthine, and armepavine on expression and activation of NF-κB in MOLT-4 cells, MOLT-4/DNR cells, peripheral blood mononuclear cells (PBMCs) of healthy s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b14388581aee78cf96fe4b11bfeb2cff
https://doi.org/10.1007/s00044-020-02624-2

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