Zobrazeno 1 - 10
of 77
pro vyhledávání: '"Haruka YOSHIDA"'
Autor:
Hiroyuki Mizuguchi, Yuko Miyamoto, Takuma Terao, Haruka Yoshida, Wakana Kuroda, Yoshiaki Kitamura, Noriaki Takeda, Hiroyuki Fukui
Publikováno v:
Current Issues in Molecular Biology, Vol 43, Iss 3, Pp 1243-1254 (2021)
Histamine H1 receptor (H1R) is one of the targets of histamine in the nervous system and the peripheral tissues. Protein kinase Cδ (PKCδ) signaling is involved in histamine-induced upregulation of H1R gene expression in HeLa cells. Histamine also u
Externí odkaz:
https://doaj.org/article/c49e66bbf01d4a078f6aa83ae05b058a
Autor:
Tetsuo Mashima, Takeru Wakatsuki, Naomi Kawata, Myung-Kyu Jang, Akiko Nagamori, Haruka Yoshida, Kenichi Nakamura, Toshiro Migita, Hiroyuki Seimiya, Kensei Yamaguchi
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract The vascular endothelial growth factor (VEGF)/VEGF receptor (VEGFR) axis is an essential regulator of angiogenesis and important therapeutic target in cancer. Ramucirumab is an anti-VEGFR2 monoclonal antibody used for the treatment of severa
Externí odkaz:
https://doaj.org/article/422426adde034efd8700a487b51f4081
Publikováno v:
JA Clinical Reports, Vol 7, Iss 1, Pp 1-3 (2021)
Abstract Background Cannulation of a central venous catheter is sometimes associated with serious complications. When arterial cannulation occurs, attention must be given to removal of a catheter. Case presentation A 62-year-old man was planned for e
Externí odkaz:
https://doaj.org/article/4c043e8a17104b119364b8296b7215eb
Autor:
Takahiro Nakamura, Sachiko Okabe, Haruka Yoshida, Keisuke Iida, Yue Ma, Shogo Sasaki, Takao Yamori, Kazuo Shin-ya, Ichiro Nakano, Kazuo Nagasawa, Hiroyuki Seimiya
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Abstract G-quadruplex (G4) is a higher-order nucleic acid structure that is formed by guanine-rich sequences. G4 stabilization by small-molecule compounds called G4 ligands often causes cytotoxicity, although the potential medicinal impact of this ef
Externí odkaz:
https://doaj.org/article/3aa433890e6a4fbf9414876c5f696dba
Autor:
Tomoya TAMURA, Chikara KUDO, Haruhi SHONO, Saori SAKAMOTO, Toru OGATA, Haruka YOSHIDA, Ena CHIBA
Publikováno v:
Journal of the Japan Veterinary Medical Association. 76:e116-e121
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4a6c3859b7f92dc3e3928e065f808463
https://doi.org/10.12935/jvma.76.e116
https://doi.org/10.12935/jvma.76.e116
Autor:
Hiroyuki Seimiya, Yoshikazu Sugimoto, Naoya Fujita, Satoshi Nagayama, Ryohei Katayama, Masaaki Matsuura, Kento Nakata, Yukiko Muramatsu, Haruka Yoshida, Bo Gong, Aki Aoyama, Ayana Sato, Anna Mizutani, Tetsuo Mashima, Noritaka Tanaka
In most colorectal cancers, Wnt/β-catenin signaling is activated by loss-of-function mutations in the adenomatous polyposis coli (APC) gene and plays a critical role in tumorigenesis. Tankyrases poly(ADP-ribosyl)ate and destabilize Axins, a negative
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8058dabfd4016a1add46858c13f4ab3e
https://doi.org/10.1158/1535-7163.c.6538768
https://doi.org/10.1158/1535-7163.c.6538768
Autor:
Hiroyuki Seimiya, Yoshikazu Sugimoto, Naoya Fujita, Satoshi Nagayama, Ryohei Katayama, Masaaki Matsuura, Kento Nakata, Yukiko Muramatsu, Haruka Yoshida, Bo Gong, Aki Aoyama, Ayana Sato, Anna Mizutani, Tetsuo Mashima, Noritaka Tanaka
Supplementary Figure S1: Full scans of the immunoblots shown in Figs. 1C, 2A and 4A. Supplementary Figure S2: Basal expression of tankyrase, Axins, and β-catenin and intracellular localization of β-catenin in CRC cell lines used in this study. Supp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ae13bad0fba3f6dc4a70c7ff8b0ef43
https://doi.org/10.1158/1535-7163.22507726.v1
https://doi.org/10.1158/1535-7163.22507726.v1
Autor:
Hiroyuki Seimiya, Yoshikazu Sugimoto, Naoya Fujita, Satoshi Nagayama, Ryohei Katayama, Masaaki Matsuura, Kento Nakata, Yukiko Muramatsu, Haruka Yoshida, Bo Gong, Aki Aoyama, Ayana Sato, Anna Mizutani, Tetsuo Mashima, Noritaka Tanaka
Legends for Supplementary Figure S1-S8
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9c208e1d39930ee1ab90fbc4958f76a
https://doi.org/10.1158/1535-7163.22507732.v1
https://doi.org/10.1158/1535-7163.22507732.v1
Autor:
Hiroyuki Seimiya, Yoshikazu Sugimoto, Naoya Fujita, Satoshi Nagayama, Ryohei Katayama, Masaaki Matsuura, Kento Nakata, Yukiko Muramatsu, Haruka Yoshida, Bo Gong, Aki Aoyama, Ayana Sato, Anna Mizutani, Tetsuo Mashima, Noritaka Tanaka
Multiple regression analysis of tankyrase inhibitor sensitivities and genetic mutations in colorectal cancer cell lines
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cbf039b732b086df7e454dda2d5cb49a
https://doi.org/10.1158/1535-7163.22507720.v1
https://doi.org/10.1158/1535-7163.22507720.v1
Autor:
Hiroyuki Seimiya, Tohru Natsume, Shun-ichiro Iemura, Akio Saiura, Yuichi Ishikawa, Mao Miyake, Yukiko Muramatsu, Toshiro Migita, Masamichi Katori, Haruka Yoshida, Tomokazu Ohishi
Tankyrase, a PARP that promotes telomere elongation and Wnt/β-catenin signaling, has various binding partners, suggesting that it has as-yet unidentified functions. Here, we report that the tankyrase-binding protein TNKS1BP1 regulates actin cytoskel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ccd358cd4767f7d534763c48969897e0
https://doi.org/10.1158/0008-5472.c.6509610.v1
https://doi.org/10.1158/0008-5472.c.6509610.v1