Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Haruka Sekiguchi"'
Autor:
Tomoko Kuroyanagi, Yuka Kobayashi, Hiroaki Ohno, Nobutaka Fujii, Kenichi Akaji, David Rhainds, Shinya Oishi, Nikolaus Heveker, Kazuya Kobayashi, Haruka Sekiguchi
Publikováno v:
Journal of Medicinal Chemistry. 61:3745-3751
The atypical chemokine receptor 3 (ACKR3)/CXC chemokine receptor 7 (CXCR7) recognizes stromal cell-derived factor 1 (SDF-1)/CXCL12 and is involved in a number of physiological and pathological processes. Here, we investigated the SAR of the component
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1024efe1537e6cf6b443707d5ff9736f
https://doi.org/10.1021/acs.jmedchem.8b00336
https://doi.org/10.1021/acs.jmedchem.8b00336
Autor:
Daisuke Nishiyama, Haruka Sekiguchi, Nobutaka Fujii, Shinya Oishi, Hiroaki Ohno, Hiroaki Chiba, Yuki Sakai, Ryosuke Misu
Publikováno v:
CHEMICAL & PHARMACEUTICAL BULLETIN. 64:996-1003
A series of novel 3,4,7-trisubstituted benzofuran derivatives were synthesized, and their binding affinity to κ- (KOR) and μ-opioid receptors (MOR) were evaluated. Several aryl ethers showed moderate binding activities to KOR (IC50=3.9-11 µM) with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d635e7aabcc0cbec99854c0f8f0d41c3
https://doi.org/10.1248/cpb.c16-00302
https://doi.org/10.1248/cpb.c16-00302