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of 6
pro vyhledávání: '"Haruka Narimatsu"'
Autor:
Kumiko Taguchi, Mari Hida, Mami Hasegawa, Haruka Narimatsu, Takayuki Matsumoto, Tsuneo Kobayashi
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-14 (2017)
Abstract Despite the associations between diabetic complications and vascular endothelial dysfunction, a direct therapeutic method targeting endothelial dysfunction remains poorly characterized. We have previously shown that chemical inhibition of G-
Externí odkaz:
https://doaj.org/article/6089618781004106a9ed062aad57b2e5
Autor:
Haruka Narimatsu, Nanami Bessho, Tsuneo Kobayashi, Mari Hida, Takayuki Matsumoto, Kumiko Taguchi
Publikováno v:
Naunyn-Schmiedeberg's Archives of Pharmacology. 391:1075-1083
Abnormal G protein-coupled receptor kinase 2 (GRK2) accumulation has a crucial role in the development of insulin resistance and diabetes. Although GRK2 siRNA transfection in the liver improves insulin resistance-related vascular complications, the e
Autor:
Kumiko Taguchi, Mami Hasegawa, Nanami Bessho, Haruka Narimatsu, Tsuneo Kobayashi, Takayuki Matsumoto
Publikováno v:
Hypertension Research. 41:263-274
Hypertension and diabetes are associated with a risk of cardiovascular disease. Clonidine is currently used as a fourth-line drug therapy for hypertension because of its rebound hypertensive effect and short half-life. The purpose of this study was t
Publikováno v:
The Journal of endocrinology. 241(3)
Endothelial dysfunction is a hallmark of diabetic vascular complications. Microparticles (MPs) are small vesicles shed from the surface of blood and vascular cells that act as stimuli and during apoptosis. Circulating MPs of diabetic rats have been s
Publikováno v:
Pflügers Archiv - European Journal of Physiology. 469:293-302
In various diseases, including diabetes, extracellular vesicles (EVs) have been detected in circulation and tissues. EVs are small membrane vesicles released from various cell types under varying conditions. Recently, endothelial cell-derived EVs (EE
Publikováno v:
Journal of Endocrinology; Jun2019, Vol. 241 Issue 3, p221-233, 13p