Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Haruka Munakata"'
Autor:
Naoko Kagawa, Eriko Isogai, Haruka Munakata, Megumi Saito, Yuichi Wakabayashi, Tatsuo Fukagawa, Kazuhiro Okumura
Publikováno v:
Cancer Science
CENP‐50/U is a component of the CENP‐O complex (CENP‐O/P/Q/R/U) and localizes to the centromere throughout the cell cycle. Aberrant expression of CENP‐50/U has been reported in many types of cancers. However, as Cenp‐50/U‐deficient mice d
Autor:
Midori Yamaguchi, Hiroshi Shitara, Kazuhiro Okumura, Ryo Kominami, Eriko Isogai, Yuichi Wakabayashi, Ikuo Miura, Megumi Saito, Andrew C. Karaplis, Choji Taya, Shigeharu Wakana, Haruka Munakata, Yasuhiro Yoshizawa
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-15 (2017)
Scientific Reports
Scientific Reports
Using a forward genetics approach to map loci in a mouse skin cancer model, we previously identified a genetic locus, Skin tumour modifier of MSM 1 (Stmm1) on chromosome 7, conferring strong tumour resistance. Sub-congenic mapping localized Parathyro
Autor:
Megumi Saito, Haruka Munakata, Yuichi Wakabayashi, Eriko Isogai, Kazuhiro Okumura, Yasuhiro Yoshizawa
Publikováno v:
Journal of Biosciences and Medicines. :53-65
Previous studies have shown that Meis1 plays an important role in the pathogenesis of acute myeloid leukemia (AML) and acute lymphoblastic leukemia (ALL). Meis1 belongs to the TALE family, the members of which are used as biomarkers for AML. Meis1 ha
Autor:
Kazuhiro Okumura, Haruka Munakata, Yuichi Wakabayashi, Eriko Isogai, Naoko Kagawa, Yasuhiro Yoshizawa, Tatsuo Fukagawa, Megumi Saito
Publikováno v:
Cancer Science
CENP‐R is a component of the CENP‐O complex, including CENP‐O, CENP‐P, CENP‐Q, CENP‐R, and CENP‐U and is constitutively localized to kinetochores throughout the cell cycle in vertebrates. CENP‐R‐deficient chicken DT40 cells are viab
Autor:
Itsuko Yoshizawa, Ken-ichi Fujita, Shinji Itoh, Takashi Satoh, Haruka Munakata, Tetsuya Kamataki, Shungo Itoh
Publikováno v:
Biological and Pharmaceutical Bulletin. 26:695-700
A study was investigated on the inhibitory effect of 29 drugs that have been reported to induce gynecomastia on the 2-hydroxylation of estradiol (E2) by recombinant P450 CYP3A4 and on the 17-oxidation of E2 by hepatic microsomal type II 17beta-hydrox
Autor:
Takashi Satoh, Ken-ichi Fujita, Haruka Munakata, Shinji Itoh, Katsunori Nakamura, Tetsuya Kamataki, Shungo Itoh, Itsuo Yoshizawa
Publikováno v:
Analytical Biochemistry. 286:179-186
To establish a prediction system for drug-induced gynecomastia in clinical fields, a model reaction system was developed to explain numerically this side effect. The principle is based on the assumption that 50% inhibition concentration (IC(50)) of d