Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Haruka Kawahara"'
Autor:
Naoki Miyashita, Keiichiro Okuhira, Koki Tachibana, Tatsuhiro Ishida, Yusuke Tsuda, Akira Otaka, Kohei Tsuji, Akira Shigenaga, Haruka Kawahara, Kyohei Morimoto
Publikováno v:
Biologicalpharmaceutical bulletin. 42(6)
Apolipoprotein A-I (apoA-I) plays a critical role in high-density lipoprotein (HDL) biogenesis, function and structural dynamics. Peptides that mimic apoA-I have a short amphipathic α-helical structure that can functionally recapitulate many of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb35eac5ec67678c89cf62262386fdbd
https://pubmed.ncbi.nlm.nih.gov/31155576
https://pubmed.ncbi.nlm.nih.gov/31155576
Autor:
Norihito Shibata, Yuichi Hashimoto, Risa Omura, Hiroyuki Saito, Keiichiro Okuhira, Susumu Itoh, Haruka Kawahara, Takayuki Hattori, Yukihiro Itoh, Mikihiko Naito, Ryo Sugihara, Yosuke Demizu, Asato Ichino, Takuji Shoda, Minoru Ishikawa, Masaaki Kurihara, Nobumichi Ohoka
Publikováno v:
Molecular pharmacology. 91(3)
Development of novel small molecules that selectively degrade pathogenic proteins would provide an important advance in targeted therapy. Recently, we have devised a series of hybrid small molecules named SNIPER (specific and nongenetic IAP-dependent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e511dc20e2dc860a80ba7252f7293d7c
https://pubmed.ncbi.nlm.nih.gov/27965304
https://pubmed.ncbi.nlm.nih.gov/27965304
Publikováno v:
Cancer science. 101(6)
Sunitinib malate (Sutent, SU11248) is a small-molecule multitargeted tyrosine kinase inhibitor (TKI) used for the treatment of renal cell carcinoma and imatinib-resistant gastrointestinal stromal tumors. Some TKIs can overcome multidrug resistance co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d6ab615fe2d40b2e4d6cfe554960b2a
https://pubmed.ncbi.nlm.nih.gov/20345483
https://pubmed.ncbi.nlm.nih.gov/20345483
Substrate-dependent bidirectional modulation of P-glycoprotein-mediated drug resistance by erlotinib
Autor:
Junko Mitsuhashi, Kohji Noguchi, Yoshikazu Sugimoto, Haruka Kawahara, Kazuhiro Katayama, Airi Kaji
Publikováno v:
Cancer science. 100(9)
Epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs) inhibit the function of certain adenosine triphosphate (ATP)-binding cassette transporters, including P-glycoprotein/ABCB1 and breast cancer resistance protein (BCRP)/ABCG2. We p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abf36b30041b5e442294280da1d7977e
https://pubmed.ncbi.nlm.nih.gov/19493273
https://pubmed.ncbi.nlm.nih.gov/19493273