Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Haruichi Kohno"'
Autor:
Daisuke Maruoka, Yuichi Koike, Takahiro Nishimura, Hideaki Nagai, Koichiro Atsuda, Masahiro Kobayashi, Haruichi Kohno
Publikováno v:
Drug Research. 70:199-205
In Japan, tuberculosis has been recognized as one of the major infections requiring urgent measures because of its high morbidity rate even now especially in elderly people suffering from tuberculosis during the past epidemic and its reactivation. He
Publikováno v:
Rinsho yakuri/Japanese Journal of Clinical Pharmacology and Therapeutics. 37:353-357
Publikováno v:
Rinsho yakuri/Japanese Journal of Clinical Pharmacology and Therapeutics. 32:7-13
In the metabolism of drugs, as in chemical substances, acetylation is one example of the most common pattern of genetic polymorphism. We established an easy, rapid and specific method of distinguishing the genetic polymorphism of N-acetyltransferase,
Publikováno v:
Rinsho yakuri/Japanese Journal of Clinical Pharmacology and Therapeutics. 23:599-603
1. Determination of isoniazid acetylation phenotype was carried out in 213 Japanese patients with pulmonary tuberculosis (control group) and 52 Japanese patients with both non-insulin-dependent diabetes mellitus and pulmonary tuberculosis (NIDDM grou
Publikováno v:
Rinsho yakuri/Japanese Journal of Clinical Pharmacology and Therapeutics. 23:665-671
The genetically controlled isoniazid N-acetylation capacity was determined in 340 unrelated Japanese subjects residing in Japan. After an oral dose of 300 or 400mg of isoniazid, the “molar acetylation ratio” (INH/AcINH) in 8hr urine was measured
Autor:
Atsushi Takada, Haruichi Kohno, Hiroaki Kubo, Nobutsugu Yoshino, Kouichi Furukawa, Takashi Suga
Publikováno v:
Rinsho yakuri/Japanese Journal of Clinical Pharmacology and Therapeutics. 22:723-730
Autor:
Haruichi, Kohno
Publikováno v:
Nihon rinsho. Japanese journal of clinical medicine. 62
Publikováno v:
American journal of therapeutics. 3(1)
The N-acetylation phenotyping of isoniazid (INH) was studied in 434 unrelated Japanese pulmonary tuberculosis patients. The frequency of slow acetylators was determined using three methods based on the urinary levels of INH and AcINH: percentage acet
Publikováno v:
Therapeutic drug monitoring. 13(5)
A rapid, simple, and accurate method has been developed for the determination of isoniazid and its metabolites (isonicotinic acid, isonicotinylglycine, and acetylisoniazid) in human urine by high-performance liquid chromatography. Isoniazid and its m
Publikováno v:
Rinsho yakuri/Japanese Journal of Clinical Pharmacology and Therapeutics. 13:403-412