Zobrazeno 1 - 10
of 143
pro vyhledávání: '"Haruhito A Uchida"'
Autor:
Satoshi Yamaguchi, Koki Mise, Jun Wada, Kenichi Shikata, Takashi Matsuoka, Haruhito A Uchida, Asami Ueno, Yasuhiro Onishi, Ayaka Kanno, Ichiro Nojima, Chigusa Higuchi, Satoshi Miyamoto, Atsuko Nakatsuka, Jun Eguchi, Kazuyuki Hida, Akihiro Katayama, Mayu Watanabe, Tatsuaki Nakato, Atsuhito Tone, Sanae Teshigawara, Shinji Kamei, Kazutoshi Murakami, Ikki Shimizu, Katsuhito Miyashita, Shinichiro Ando, Tomokazu Nunoue
Publikováno v:
BMJ Open Diabetes Research & Care, Vol 12, Iss 3 (2024)
Introduction ACE cleaves angiotensin I (Ang I) to angiotensin II (Ang II) inducing vasoconstriction via Ang II type 1 (AT1) receptor, while ACE2 cleaves Ang II to Ang (1–7) causing vasodilatation by acting on the Mas receptor. In diabetic kidney di
Externí odkaz:
https://doaj.org/article/c9419a733e74406e84a4c4daa6de173f
Autor:
Ayu Ogawa-Akiyama, Hitoshi Sugiyama, Masashi Kitagawa, Keiko Tanaka, Yuzuki Kano, Koki Mise, Nozomu Otaka, Katsuyuki Tanabe, Hiroshi Morinaga, Masaru Kinomura, Haruhito A Uchida, Jun Wada
Publikováno v:
PLoS ONE, Vol 15, Iss 1, p e0228337 (2020)
Autophagy is a cellular mechanism involved in the bulk degradation of proteins and turnover of organelle. Several studies have shown the significance of autophagy of the renal tubular epithelium in rodent models of tubulointerstitial disorder. Howeve
Externí odkaz:
https://doaj.org/article/5ac617b63b12447b9953063618472413
Autor:
Hidemi Takeuchi, Michihiro Okuyama, Haruhito A Uchida, Yuki Kakio, Ryoko Umebayashi, Yuka Okuyama, Yasuhiro Fujii, Susumu Ozawa, Masashi Yoshida, Yu Oshima, Shunji Sano, Jun Wada
Publikováno v:
PLoS ONE, Vol 11, Iss 10, p e0164015 (2016)
Chronic kidney disease (CKD) and diabetes mellitus (DM) are considered as risk factors for cardiovascular diseases. The purpose of this study was to clarify the relationship of CKD and DM with the presence of abdominal aortic aneurysm (AAA).We enroll
Externí odkaz:
https://doaj.org/article/82b8ba10764542d09892307802c3db4e
Autor:
Venkateswaran Subramanian, Jessica J Moorleghen, Anju Balakrishnan, Deborah A Howatt, Athar H Chishti, Haruhito A Uchida
Publikováno v:
PLoS ONE, Vol 8, Iss 8, p e72214 (2013)
Recently, we demonstrated that angiotensin II (AngII)-infusion profoundly increased both aortic protein and activity of calpains, calcium-activated cysteine proteases, in mice. In addition, pharmacological inhibition of calpain attenuated AngII-induc
Externí odkaz:
https://doaj.org/article/8c3d5f1a7ba248e4b6ecff2b43819199
Autor:
Ryoko Umebayashi, Natsumi Matsuoka-Uchiyama, Hitoshi Sugiyama, Kenichi Shikata, Naoki Kashihara, Hirofumi Makino, Jun Wada, Haruhito A. Uchida
Publikováno v:
Diseases, Vol 12, Iss 11, p 268 (2024)
CKD public education plays a very important role in effective chronic kidney disease (CKD) countermeasure. We have been conducting CKD public education programs in Okayama Prefecture since 2007. Here, we aimed to examine the actual status of CKD perc
Externí odkaz:
https://doaj.org/article/c70b7ae28ce44f93abb3435a36739d8f
Autor:
Natsumi Matsuoka-Uchiyama, Kenji Tsuji, Yizhen Sang, Kensaku Takahashi, Kazuhiko Fukushima, Hidemi Takeuchi, Kenichi Inagaki, Haruhito A. Uchida, Shinji Kitamura, Hitoshi Sugiyama, Jun Wada
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract Hypothyroidism is known to be correlated with kidney function and nephrotic range proteinuria. However, it is uncertain whether non-nephrotic proteinuria is associated with hypothyroidism. This study aimed to evaluate the association of prot
Externí odkaz:
https://doaj.org/article/0fc8e73943844e1db6f315d0ad86c8cf
Autor:
Haruhito A. Uchida, Tetsuharu Takatsuka, Yoshiko Hada, Ryoko Umebayashi, Hidemi Takeuchi, Kenichi Shikata, Venkateswaran Subramanian, Alan Daugherty, Jun Wada
Publikováno v:
Biomolecules, Vol 12, Iss 8, p 1117 (2022)
Background: The aim of the study was to define whether edaravone, a free-radical scavenger, influenced angiotensin II (AngII)-induced atherosclerosis and abdominal aortic aneurysms (AAAs) formation. Methods: Male apolipoprotein E-deficient mice (8–
Externí odkaz:
https://doaj.org/article/fe04b3ace36548b68aef32ae5ed91359
Autor:
Takashi Goyama, Yasuhiro Fujii, Genya Muraoka, Tatsuyuki Nakatani, Daiki Ousaka, Yuichi Imai, Noriaki Kuwada, Tatsunori Tsuji, Takayuki Shuku, Haruhito A. Uchida, Masahiro Nishibori, Susumu Oozawa, Shingo Kasahara
Publikováno v:
Scientific Reports. 13
The aim of this study was to obtain comprehensive data regarding the hemocompatibility of diamond-like carbon (DLC)-coated expanded polytetrafluoroethylene (ePTFE). DLC increased hydrophilicity of the ePTFE surface and made ePTFE fibers smoother. DLC
Autor:
Takahiko Sugihara, Hajime Yoshifuji, Haruhito A Uchida, Yasuhiro Maejima, Yoshiko Watanabe, Kazuo Tanemoto, Natsuka Umezawa, Yusuke Manabe, Jun Ishizaki, Tsuyoshi Shirai, Hiroko Nagafuchi, Hitoshi Hasegawa, Hiroaki Niiro, Tomonori Ishii, Yoshikazu Nakaoka, Masayoshi Harigai
Publikováno v:
Modern Rheumatology.
Objective To develop a proposal for giant cell arteritis (GCA) remission criteria in order to implement a treat-to-target algorithm. Methods A task force consisting of 10 rheumatologists, three cardiologists, one nephrologist, and one cardiac surgeon
Autor:
Keiko Tanaka, Hitoshi Sugiyama, Hiroshi Morinaga, Akifumi Onishi, Yuzuki Kano, Hidemi Takeuchi, Kenji Tsuji, Motoki Kubo, Katsuyuki Tanabe, Haruhito A. Uchida, Kazufumi Nakamura, Jun Wada
Publikováno v:
Annals of Internal Medicine: Clinical Cases. 2