Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Haruhiro Takenoshita"'
Autor:
Shuichi Ando, Tsunehiko Soga, Ikuo Mitsui, Hirofumi Terasawa, Kouichi Uoto, Haruhiro Takenoshita, Yasuhide Hirota, Toshiharu Yoshino
Publikováno v:
Chemical and Pharmaceutical Bulletin. 46:770-776
To develop non-prodrugs of taxoids with satisfactory stability in vivo, high water-solubility, and potent antitumor activity, we prepared several 10-O-sec-aminoethyl docetaxel analogs (3) and evaluated their cytotoxicity against mouse leukemia and hu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b57cf8754b51c033a35a13f828c8b66
https://doi.org/10.1248/cpb.46.770
https://doi.org/10.1248/cpb.46.770
Publikováno v:
ChemInform. 22
In the presence of a catalytic amount of a transition metal compound such as [Rh(COD)Cl]2, Co(acac)2, or NiCl2, trimethylsilyl cyanide smoothly reacts with acetals to form α-methoxy carbonitriles in good yields. In the coexistence of catalytic amoun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7f3e236f3e173e4fb7a319806e8ea659
https://doi.org/10.1002/chin.199114098
https://doi.org/10.1002/chin.199114098
Publikováno v:
ChemInform. 22
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6aa03ef1c4d811a3fd47b9b29068398c
https://doi.org/10.1002/chin.199135129
https://doi.org/10.1002/chin.199135129
Publikováno v:
ChemInform. 22
In the presence of a catalytic amount of trityl perchlorate, trimethylsilyl cyanide reacts with the dimethyl acetals of chalcone derivatives, with simultaneous double bond isomerization, to yield γ-methoxy-α,β-unsaturated carbonitriles. Trimethyls
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::faa0aa126d88ffa1c8424f299aff4046
https://doi.org/10.1002/chin.199131072
https://doi.org/10.1002/chin.199131072
Autor:
Kouichi Uoto, Shin Iimura, Takashi Ishiyama, Satoru Ohsuki, Hirofumi Terasawa, Haruhiro Takenoshita, Tsunehiko Soga, Ikuo Mitsui, Y. Hirota
Publikováno v:
ChemInform. 29
To investigate the role of the 2'-hydroxy group at the C-13 side chain of docetaxel in the antitumor activity, we prepared several 2',2'-difluoro derivatives of docetaxel and evaluated their cytotoxicity against mouse leukemia and human tumor cell li
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::086fec225b515a690c2296da4f4795e2
https://doi.org/10.1002/chin.199818200
https://doi.org/10.1002/chin.199818200
Publikováno v:
ChemInform. 29
We have developed a new method to modify the C-4 position of 10-deacetylbaccatin III (5) using the C-4 acetoxy anion of the 13-keto derivative (7) and various alkyl halides. The method developed herein shound be very useful for the preparation of C-4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c48879d38e3b21e1b4754ca0c3260d8f
https://doi.org/10.1002/chin.199822127
https://doi.org/10.1002/chin.199822127
Autor:
Kouichi Uoto, Haruhiro Takenoshita, Hirofumi Terasawa, Y. Hirota, Tsunehiko Soga, Ikuo Mitsui, S. Ando, Toshiharu Yoshino
Publikováno v:
ChemInform. 29
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0dbbec3dcf469a15986f486a3e29eace
https://doi.org/10.1002/chin.199847205
https://doi.org/10.1002/chin.199847205
Publikováno v:
Bulletin of the Chemical Society of Japan. 64:1108-1117
In the presence of a catalytic amount of trityl perchlorate, trimethylsilyl cyanide reacts with the dimethyl acetals of chalcone derivatives, with simultaneous double bond isomerization, to yield γ-methoxy-α,β-unsaturated carbonitriles. Trimethyls
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::01dbd554d109138ebcd60dd415b3b450
https://doi.org/10.1246/bcsj.64.1108
https://doi.org/10.1246/bcsj.64.1108
Publikováno v:
Bulletin of the Chemical Society of Japan. 63:3122-3131
In the presence of a catalytic amount of a transition metal compound such as [Rh(COD)Cl]2, Co(acac)2, or NiCl2, trimethylsilyl cyanide smoothly reacts with acetals to form α-methoxy carbonitriles in good yields. In the coexistence of catalytic amoun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eaecd87d812bec70b524342020e2ed67
https://doi.org/10.1246/bcsj.63.3122
https://doi.org/10.1246/bcsj.63.3122
Publikováno v:
Bulletin of the Chemical Society of Japan. 63:1898-1915
In the presence of a catalytic amount of triphenylmethylium hexachloroantimonate or a catalyst system of antimony pentachloride, chlorotrimethylsilane and tin(II) iodide, α-substituted cyclic ethers are stereoselectively prepared from lactones by su
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4003efa5e627db0d38cbc950b5b579b6
https://doi.org/10.1246/bcsj.63.1898
https://doi.org/10.1246/bcsj.63.1898