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pro vyhledávání: '"Haruhiko Yanagisama"'
Autor:
Hiroshi Wakui, Kenji Kobayashi, Kazuyoshi Kuwano, Nahoko Sato, Saburo Ito, Haruhiko Yanagisama, Hironori Kawamoto, Akihiro Ichikawa, Masahiro Yoshida, Jun Araya, Akihiko Ito, Takanori Numata, Hiromochi Hara, Kazuya Tsubouchi, Yumi Kaneko, Yusuke Kurita, Tsukasa Kadota, Shunsuke Minagawa, Katsutoshi Nakayama, Mitsuo Hashimoto, Takeo Ishikawa, Hirofumi Utsumi, Nayuta Saito
Publikováno v:
Airway Cell Biology and Immunopathology.
Introduction: Downregulation of lamin B1 has been recognized to be a crucial step for development of full senescence. Accelerated cellular senescence linked to dysregulated autophagy and mTOR activation have been implicated in COPD pathogenesis. We h