Zobrazeno 1 - 10
of 102
pro vyhledávání: '"Haruhiko Ninomiya"'
Autor:
Kazuhiro Miyata, Yuichi Aita, Syuichi Nakajima, Michiharu Sekimoto, Yukako Setaka, Yoshika Tagoya, Toshiyuki Aoyama, Takami Maeno, Masahiko Monma, Kazuhide Tomita, Haruhiko Ninomiya
Publikováno v:
PLoS ONE, Vol 17, Iss 7, p e0270864 (2022)
All healthcare professionals must understand information on a patient's biophysical functions, and it is important to educate professionals on how to use this information in an interprofessional team for diagnosis. However, there is little interprofe
Externí odkaz:
https://doaj.org/article/b085f564dedd451099a1be0ccfde8549
Autor:
Haruhiko Ninomiya, Naoshi Obara, Akiko Niiori-Onishi, Yasuhisa Yokoyama, Mamiko Sakata-Yanagimoto, Yuichi Hasegawa, Shigeru Chiba
Publikováno v:
Case Reports in Hematology, Vol 2015 (2015)
Chronic kidney disease (CKD) is one of the major manifestations of paroxysmal nocturnal hemoglobinuria (PNH). CKD in PNH is induced mainly by intravascular hemolysis of PNH-affected red blood cells (RBC) missing the glycosylphosphatidylinositol-ancho
Externí odkaz:
https://doaj.org/article/fa18285b545242e9bf20f2a7b7147bde
Autor:
Taro Ishigaki, Kazuhiro Sudo, Takashi Hiroyama, Kenichi Miharada, Haruhiko Ninomiya, Shigeru Chiba, Toshiro Nagasawa, Yukio Nakamura
Publikováno v:
Advances in Hematology, Vol 2009 (2009)
We previously reported that long-lasting in vitro hematopoiesis could be achieved using the cells differentiated from primate embryonic stem (ES) cells. Thus, we speculated that hematopoietic stem cells differentiated from ES cells could sustain long
Externí odkaz:
https://doaj.org/article/239854b7131f4c4586264a055960f650
Autor:
Takayuki Ikezoe, Hideyoshi Noji, Yasutaka Ueda, Yoshinobu Kanda, Shinichiro Okamoto, Kensuke Usuki, Takahisa Matsuda, Hirozumi Akiyama, Akihiko Shimono, Yuji Yonemura, Tatsuya Kawaguchi, Shigeru Chiba, Yuzuru Kanakura, Jun‑ichi Nishimura, Haruhiko Ninomiya, Naoshi Obara
Publikováno v:
International Journal of Hematology. 115:470-480
All Japanese patients with paroxysmal nocturnal hemoglobinuria (PNH) treated with eculizumab were enrolled in post-marketing surveillance (PMS) between June 2010 and August 2019 to assess the long-term effectiveness and safety of eculizumab. The redu
Autor:
Kohei Hosokawa, Ken Ishiyama, Haruhiko Ninomiya, Yuji Yonemura, Chiharu Sugimori, Mai Anh Thi Nguyen, Yukari Shirasugi, Toshiyuki Ikemoto, Yoshihiko Nakamura, Tsutomu Shichishima, Shinji Nakao, Shigeru Chiba, Yasutaka Ueda, Junichi Nishimura, Yuzuru Kanakura, Tatsuya Kawaguchi, Hideyoshi Noji, Naoshi Obara, Kiyoshi Ando
Publikováno v:
Annals of Hematology. 100:1975-1982
Small populations of glycosylphosphatidylinositol-anchored protein-deficient (GPI[-]) cells accounting for up to 0.01% of total granulocytes can be accurately detected by a high-sensitivity flow cytometry (FCM) assay established by the Clinical and L
Autor:
Sung Soo Yoon, Hubert Schrezenmeier, Jin Seok Kim, Simona Sica, Kensuke Usuki, Juliette Soret, Jens Panse, Alexandre Sostelly, Junichi Nishimura, Flore Sicre de Fontbrune, Marta Biedzka-Sarek, Brittany Gentile, Judith Anzures-Cabrera, Yoshikazu Ito, Régis Peffault de Latour, Barbara Klughammer, Christoph Bucher, Satoshi Ichikawa, Gregor Jordan, Zsolt Nagy, Andreas Dieckmann, Miklos Egyed, Angelika Jahreis, Alexander Röth, James Higginson, Haruhiko Ninomiya, Kenji Shinomiya, Júlia Gaál-Weisinger
Publikováno v:
Blood. 135:912-920
Complement C5 inhibition is the standard of care (SoC) for patients with paroxysmal nocturnal hemoglobinuria (PNH) with significant clinical symptoms. Constant and complete suppression of the terminal complement pathway and the high serum concentrati
Autor:
Haruhiko Ninomiya, Yukako Setaka, Michiharu Sekimoto, Toshiyuki Aoyama, Kazuhide Tomita, Yuichi Aita, Yukari Ohashi
Publikováno v:
Journal of allied health sciences. 10:10-18
Autor:
Junichi Nishimura, Yuzuru Kanakura, Yasutaka Ueda, Naoshi Obara, Hideyoshi Noji, Kiyoshi Ando, Hiroyuki Takamori, Tsutomu Shichishima, Shinji Nakao, Yuji Yonemura, Takayuki Ikezoe, Ken Ishiyama, Haruhiko Ninomiya, Kohei Hosokawa, Tatsuya Kawaguchi, Shigeru Chiba
Publikováno v:
Blood. 138:1122-1122
Background: Small populations of paroxysmal nocturnal hemoglobinuria (PNH)-type cells ( Methods: Patients diagnosed with PNH, AA, MDS or indistinguishable BMF without malignant diseases were prospectively recruited to the study between April 1 st, 20
Autor:
Anna Kiialainen, Antoine Soubret, Simon Buatois, Jules Hernández-Sánchez, Sasha Sreckovic, Sung-Soo Yoon, Jens Panse, Alexander Röth, Régis Peffault de Latour, Haruhiko Ninomiya, Jin Seok Kim, Hubert Schrezenmeier, Ido Paz-Priel, Simona Sica, Julia Ramos, Junichi Nishimura, Alexandre Sostelly
Publikováno v:
Blood. 136:6-7
Background Inhibition of complement C5 is the current standard of care for paroxysmal nocturnal hemoglobinuria (PNH). C5 inhibition reduces transfusion requirements and improves anemia and quality of life by ameliorating intravascular hemolysis. Howe
Autor:
Naoshi Obara, Kaichi Nishiwaki, Kiyoshi Ando, Kensuke Usuki, Mitsuhiro Omine, Tatsuya Kawaguchi, Kazuma Ohyashiki, Hideki Nakakuma, Junichi Nishimura, H Akiyama, Yuzuru Kanakura, Shinichiro Okamoto, Daisuke Harada, Itaru Matsumura, Taroh Kinoshita, Haruhiko Ninomiya, Keiya Ozawa, Tsutomu Shichishima, Shinji Nakao, Shigeru Chiba, Yoshinobu Kanda
Publikováno v:
International Journal of Hematology. 104:548-558
Data characterizing the safety and effectiveness of eculizumab in patients with paroxysmal nocturnal hemoglobinuria (PNH) are limited. We describe the safety and effectiveness of eculizumab in PNH patients enrolled in a post-marketing surveillance st