Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Haruhiko Miya"'
Autor:
Shintaro Shibata, Yoichi Masui, Naoki Narukawa, Takuya Shiroshita, Haruhiko Miya, Rintaro Sato, Shunta Tokutake, Yoshiki Tanaka, Makoto Onaka
Publikováno v:
Bulletin of the Chemical Society of Japan.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bb7a7c4ec9948cbb5680b6cddd3b2ddf
https://doi.org/10.1246/bcsj.20230055
https://doi.org/10.1246/bcsj.20230055
Autor:
Takafumi Kawai, Shin Morioka, Haruhiko Miyata, Rizki Tsari Andriani, Sharmin Akter, Gabriel Toma, Tatsuya Nakagawa, Yuki Oyama, Rie Iida-Norita, Junko Sasaki, Masahiko Watanabe, Kenji Sakimura, Masahito Ikawa, Takehiko Sasaki, Yasushi Okamura
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Voltage-sensing phosphatase (VSP) exhibits voltage-dependent phosphatase activity toward phosphoinositides. VSP generates a specialized phosphoinositide environment in mammalian sperm flagellum. However, the voltage-sensing mechanism of VSP
Externí odkaz:
https://doaj.org/article/516aace4a4d64270b00fbb8aebb6be24
Autor:
Takahiro Akamine, Takeshi Terabayashi, Takako Sasaki, Riku Hayashi, Ichitaro Abe, Fumihiro Hirayama, Shin‐ichi Nureki, Masahito Ikawa, Haruhiko Miyata, Akinori Tokunaga, Takashi Kobayashi, Katsuhiro Hanada, Dean Thumkeo, Shuh Narumiya, Toshimasa Ishizaki
Publikováno v:
FEBS Open Bio, Vol 14, Iss 6, Pp 906-921 (2024)
The Ras homology (Rho) family of GTPases serves various functions, including promotion of cell migration, adhesion, and transcription, through activation of effector molecule targets. One such pair of effectors, the Rho‐associated coiled‐coil kin
Externí odkaz:
https://doaj.org/article/55c8cc91eaf9494c8af4f125e026844e
Autor:
Yuki Kaneda, Haruhiko Miyata, Zoulan Xu, Keisuke Shimada, Maki Kamoshita, Tatsuya Nakagawa, Chihiro Emori, Masahito Ikawa
Publikováno v:
eLife, Vol 13 (2024)
Ribonucleoprotein (RNP) granules are membraneless electron-dense structures rich in RNAs and proteins, and involved in various cellular processes. Two RNP granules in male germ cells, intermitochondrial cement and the chromatoid body (CB), are associ
Externí odkaz:
https://doaj.org/article/3a0a98bca3ef4f9999ead7f31f3460e5
Autor:
Haoting Wang, Rie Iida-Norita, Daisuke Mashiko, Anh Hoang Pham, Haruhiko Miyata, Masahito Ikawa
Publikováno v:
PLoS Genetics, Vol 20, Iss 6, p e1011337 (2024)
Sperm heads contain not only the nucleus but also the acrosome which is a distinctive cap-like structure located anterior to the nucleus and is derived from the Golgi apparatus. The Golgi Associated RAB2 Interactors (GARINs; also known as FAM71) prot
Externí odkaz:
https://doaj.org/article/7d3232befcf647919e47c17976cc0bd9
Multiple ageing effects on testicular/epididymal germ cells lead to decreased male fertility in mice
Autor:
Tsutomu Endo, Kiyonori Kobayashi, Takafumi Matsumura, Chihiro Emori, Manabu Ozawa, Shimpei Kawamoto, Daisuke Okuzaki, Keisuke Shimada, Haruhiko Miyata, Kentaro Shimada, Mayo Kodani, Yu Ishikawa-Yamauchi, Daisuke Motooka, Eiji Hara, Masahito Ikawa
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-16 (2024)
Abstract In mammals, females undergo reproductive cessation with age, whereas male fertility gradually declines but persists almost throughout life. However, the detailed effects of ageing on germ cells during and after spermatogenesis, in the testis
Externí odkaz:
https://doaj.org/article/623ca58762e34a14a21188196ebbee61
Autor:
Shintaro Mise, Akinobu Matsumoto, Keisuke Shimada, Toshiaki Hosaka, Masatomo Takahashi, Kazuya Ichihara, Hideyuki Shimizu, Chisa Shiraishi, Daisuke Saito, Mikita Suyama, Tomoharu Yasuda, Toru Ide, Yoshihiro Izumi, Takeshi Bamba, Tomomi Kimura-Someya, Mikako Shirouzu, Haruhiko Miyata, Masahito Ikawa, Keiichi I. Nakayama
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-17 (2022)
A number of testes-specific lncRNAs have been annotated but their roles remain largely unexplored. Here the authors identify two small peptides encoded by the lncRNA Gm9999, Kastor and Polluks, both of which are required for male fertility in mice.
Externí odkaz:
https://doaj.org/article/3779cfb8e45643108b988769fd650048
Autor:
Yuki Oyama, Haruhiko Miyata, Keisuke Shimada, Yoshitaka Fujihara, Keizo Tokuhiro, Thomas X Garcia, Martin M Matzuk, Masahito Ikawa
Publikováno v:
Asian Journal of Andrology, Vol 24, Iss 3, Pp 266-272 (2022)
Gene expression analyses suggest that more than 1000–2000 genes are expressed predominantly in mouse and human testes. Although functional analyses of hundreds of these genes have been performed, there are still many testis-enriched genes whose fun
Externí odkaz:
https://doaj.org/article/7f88ba8a95df47dfb5206782c6123575
Autor:
Kanako Kojima-Kita, Satomi Kuramochi-Miyagawa, Manabu Nakayama, Haruhiko Miyata, Steven E. Jacobsen, Masahito Ikawa, Haruhiko Koseki, Toru Nakano
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-19 (2021)
Abstract The PIWI (P-element-induced wimpy testis)-interacting-RNA (piRNA) pathway plays a crucial role in the repression of TE (transposable element) expression via de novo DNA methylation in mouse embryonic male germ cells. Various proteins, includ
Externí odkaz:
https://doaj.org/article/e4240d46cf334381916666d84f0183e3
Autor:
Yuki Oyama, Haruhiko Miyata, Keisuke Shimada, Tamara Larasati, Yoshitaka Fujihara, Masahito Ikawa
Publikováno v:
Reproductive Medicine and Biology, Vol 21, Iss 1, Pp n/a-n/a (2022)
Abstract Purpose Tulp2 (tubby‐like protein 2) is a member of the tubby protein family and expressed predominantly in mouse testis. Recently, it was reported that Tulp2 knockout (KO) mice exhibited disrupted sperm tail morphology; however, it remain
Externí odkaz:
https://doaj.org/article/a4d1e72e46fd4f91829560678d5cb692