Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Haruhide Udagawa"'
Autor:
Haruhide Udagawa, Nobuaki Funahashi, Wataru Nishimura, Takashi Uebanso, Miho Kawaguchi, Riku Asahi, Shigeru Nakajima, Takao Nammo, Masaki Hiramoto, Kazuki Yasuda
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-14 (2023)
Abstract The mechanisms of impaired glucose-induced insulin secretion from the pancreatic β-cells in obesity have not yet been completely elucidated. Here, we aimed to assess the effects of adipocyte-derived factors on the functioning of pancreatic
Externí odkaz:
https://doaj.org/article/776401123a8948508e6b6a6f4767a61c
Autor:
Haruhide Udagawa, Masaki Hiramoto, Miho Kawaguchi, Takashi Uebanso, Mica Ohara‐Imaizumi, Takao Nammo, Wataru Nishimura, Kazuki Yasuda
Publikováno v:
Journal of Diabetes Investigation, Vol 11, Iss 4, Pp 814-822 (2020)
Abstract Aims/Introduction Taste receptors, T1rs and T2rs, and the taste‐selective G‐protein, α‐gustducin, are expressed outside the taste‐sensing system, such as enteroendocrine L cells. Here, we examined whether α‐gustducin also affects
Externí odkaz:
https://doaj.org/article/95d7e6014abe493b8c3c067043a71b4d
Autor:
Koki Eto, Wataru Nishimura, Hisashi Oishi, Haruhide Udagawa, Miho Kawaguchi, Masaki Hiramoto, Toshiyoshi Fujiwara, Satoru Takahashi, Kazuki Yasuda
Publikováno v:
PLoS ONE, Vol 9, Iss 8, p e104184 (2014)
The postnatal proliferation and maturation of insulin-secreting pancreatic β-cells are critical for glucose metabolism and disease development in adults. Elucidation of the molecular mechanisms underlying these events will be beneficial to direct th
Externí odkaz:
https://doaj.org/article/c9f4d253b5bf4608a4f03cdc52bdc1a1
Autor:
Kyota, Aoyagi, Shun-Ichi, Yamashita, Yoshihiro, Akimoto, Chiyono, Nishiwaki, Yoko, Nakamichi, Haruhide, Udagawa, Manabu, Abe, Kenji, Sakimura, Tomotake, Kanki, Mica, Ohara-Imaizumi
Publikováno v:
Diabetologia. 66:147-162
Mitophagy, the selective autophagy of mitochondria, is essential for maintenance of mitochondrial function. Recent studies suggested that defective mitophagy in beta cells caused diabetes. However, because of technical difficulties, the development o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe20ea67f339d46694701b8765789cac
https://doi.org/10.1007/s00125-022-05800-8
https://doi.org/10.1007/s00125-022-05800-8
Autor:
Junko, Kuramoto, Eri, Arai, Mao, Fujimoto, Ying, Tian, Yuriko, Yamada, Takuya, Yotani, Satomi, Makiuchi, Noboru, Tsuda, Hidenori, Ojima, Moto, Fukai, Yosuke, Seki, Kazunori, Kasama, Nobuaki, Funahashi, Haruhide, Udagawa, Takao, Nammo, Kazuki, Yasuda, Akinobu, Taketomi, Tatsuya, Kanto, Yae, Kanai
Publikováno v:
Clinical Epigenetics. 14
Background In recent years, non-alcoholic steatohepatitis (NASH) has become the main cause of hepatocellular carcinoma (HCC). As a means of improving the treatment of NASH-related HCCs based on early detection, this study investigated the feasibility
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a60100fcb139b3717bceee29489e3b29
https://doi.org/10.1186/s13148-022-01379-4
https://doi.org/10.1186/s13148-022-01379-4
Autor:
Wataru Nishimura, Mica Ohara-Imaizumi, Takao Nammo, Masaki Hiramoto, Kazuki Yasuda, Haruhide Udagawa, Takashi Uebanso, Miho Kawaguchi
Publikováno v:
Journal of Diabetes Investigation
Journal of Diabetes Investigation, Vol 11, Iss 4, Pp 814-822 (2020)
Journal of Diabetes Investigation, Vol 11, Iss 4, Pp 814-822 (2020)
Aims/Introduction Taste receptors, T1rs and T2rs, and the taste‐selective G‐protein, α‐gustducin, are expressed outside the taste‐sensing system, such as enteroendocrine L cells. Here, we examined whether α‐gustducin also affects nutritio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74486dafd1f43487f2175cf2943fe5e0
https://doi.org/10.1111/jdi.13214
https://doi.org/10.1111/jdi.13214
Autor:
Junko Kuramoto, Eri Arai, Mao Fujimoto, Ying Tian, Yuriko Yamada, Takuya Yotani, Satomi Makiuchi, Noboru Tsuda, Hidenori Ojima, Moto Fukai, Yosuke Seki, Kazunori Kasama, Nobuaki Funahashi, Haruhide Udagawa, Takao Nammo, Kazuki Yasuda, Akinobu Taketomi, Tatsuya Kanto, Yae Kanai
Publikováno v:
Cancer Research. 82:5703-5703
Background: In recent years, non-alcoholic steatohepatitis (NASH) has become the main cause of hepatocellular carcinoma (HCC). As a means of improving the treatment of NASH-related HCCs based on early detection, this study investigated the feasibilit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0f3efebaa9d5297528132c87482f1419
https://doi.org/10.1158/1538-7445.am2022-5703
https://doi.org/10.1158/1538-7445.am2022-5703
Autor:
Yoshiro Maezawa, Takuya Minamizuka, Kazuki Yasuda, Masaya Koshizaka, Koutaro Yokote, Yusuke Endo, Yusuke Baba, Haruhide Udagawa
Publikováno v:
Diabetes. 69
Accumulation of visceral fat leads to insulin resistance and diabetes. Therefore, it is important to elucidate the mechanism by which adipose progenitor cells (APCs) are maintained and how they differentiate. The bHLH transcription factor 21 (Tcf21)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f65ae24b8d75baca0ff83bef45024ba5
https://doi.org/10.2337/db20-1962-p
https://doi.org/10.2337/db20-1962-p
Autor:
Wataru Nishimura, Nobuaki Funahashi, Miho Kawaguchi, Masaki Hiramoto, Takao Nammo, Kazuki Yasuda, Takashi Uebanso, Haruhide Udagawa
Publikováno v:
Diabetologia. 61:2608-2620
Epigenetic regulation of gene expression has been implicated in the pathogenesis of obesity and type 2 diabetes. However, detailed information, such as key transcription factors in pancreatic beta cells that mediate environmental effects, is not yet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab2853039a115a8b26e7a39bee018b6a
https://doi.org/10.1007/s00125-018-4735-7
https://doi.org/10.1007/s00125-018-4735-7
Autor:
Haruhide Udagawa, Wataru Nishimura, Keisuke Miyazawa, Atsushi Watanabe, Takao Nammo, Miho Kawaguchi, Naoko Ishibashi, Takashi Uebanso, Masaki Hiramoto, Kazuki Yasuda
Publikováno v:
International Journal of Molecular Medicine. 36:222-230
Although recent genome-wide association studies (GWAS) have been extremely successful, it remains a big challenge to functionally annotate disease‑associated single nucleotide polymorphisms (SNPs), as the majority of these SNPs are located in non
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d4171051c8f03663cd2f4c99f00e9a5
https://doi.org/10.3892/ijmm.2015.2203
https://doi.org/10.3892/ijmm.2015.2203