Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Hartwin Lier"'
Rapid coupling between gravitational forces and the transcriptome in human myelomonocytic U937 cells
Autor:
Cora S. Thiel, Svantje Tauber, Swantje Christoffel, Andreas Huge, Beatrice A. Lauber, Jennifer Polzer, Katrin Paulsen, Hartwin Lier, Frank Engelmann, Burkhard Schmitz, Andreas Schütte, Christiane Raig, Liliana E. Layer, Oliver Ullrich
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-24 (2018)
Abstract The gravitational force has been constant throughout Earth’s evolutionary history. Since the cell nucleus is subjected to permanent forces induced by Earth’s gravity, we addressed the question, if gene expression homeostasis is constantl
Externí odkaz:
https://doaj.org/article/44e64d0c24c0444c8c368d6412db525b
Autor:
Cora S. Thiel, Swantje Hauschild, Andreas Huge, Svantje Tauber, Beatrice A. Lauber, Jennifer Polzer, Katrin Paulsen, Hartwin Lier, Frank Engelmann, Burkhard Schmitz, Andreas Schütte, Liliana E. Layer, Oliver Ullrich
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-22 (2017)
Abstract We investigated the dynamics of immediate and initial gene expression response to different gravitational environments in human Jurkat T lymphocytic cells and compared expression profiles to identify potential gravity-regulated genes and ada
Externí odkaz:
https://doaj.org/article/cb286fb18e6c487984773382255761ca
Autor:
Svantje Tauber, Swantje Hauschild, Katrin Paulsen, Annett Gutewort, Christiane Raig, Eva Hürlimann, Josefine Biskup, Claudia Philpot, Hartwin Lier, Frank Engelmann, Antonella Pantaleo, Augusto Cogoli, Proto Pippia, Liliana E. Layer, Cora S. Thiel, Oliver Ullrich
Publikováno v:
Cellular Physiology and Biochemistry, Vol 35, Iss 3, Pp 1034-1051 (2015)
Background/Aims: Several limiting factors for human health and performance in microgravity have been clearly identified arising from the immune system, and substantial research activities are required in order to provide the basic information for app
Externí odkaz:
https://doaj.org/article/eeda18d13cf64b3f83039a039587c149
Rapid coupling between gravitational forces and the transcriptome in human myelomonocytic U937 cells
Autor:
Swantje Christoffel, Burkhard Schmitz, Frank Engelmann, Andreas Schütte, Hartwin Lier, Jennifer Polzer, Svantje Tauber, Oliver Ullrich, Cora S. Thiel, Liliana E. Layer, Katrin Paulsen, Beatrice A. Lauber, Andreas Huge, Christiane Raig
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-24 (2018)
Scientific Reports
Scientific Reports
The gravitational force has been constant throughout Earth’s evolutionary history. Since the cell nucleus is subjected to permanent forces induced by Earth’s gravity, we addressed the question, if gene expression homeostasis is constantly shaped
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67664b3e015165611036ed7f7747458d
https://doaj.org/article/44e64d0c24c0444c8c368d6412db525b
https://doaj.org/article/44e64d0c24c0444c8c368d6412db525b
Autor:
Svantje Tauber, Andreas Huge, Jennifer Polzer, Cora S. Thiel, Frank Engelmann, Andreas Schütte, Hartwin Lier, Swantje Hauschild, Burkhard Schmitz, Beatrice A. Lauber, Oliver Ullrich, Liliana E. Layer, Katrin Paulsen
Publikováno v:
NPJ Microgravity
npj Microgravity, Vol 3, Iss 1, Pp 1-20 (2017)
npj Microgravity, Vol 3, Iss 1, Pp 1-20 (2017)
In the last decades, a plethora of in vitro studies with living human cells contributed a vast amount of knowledge about cellular and molecular effects of microgravity. Previous studies focused mostly on the identification of gravity-responsive genes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84bee69c2ff41dd77820072bc62a77b8
http://europepmc.org/articles/PMC5579209
http://europepmc.org/articles/PMC5579209
Autor:
Jennifer Polzer, Cora S. Thiel, Oliver Ullrich, Liliana E. Layer, Beatrice A. Lauber, Frank Engelmann, Katrin Paulsen, Svantje Tauber, Swantje Hauschild, Andreas Schütte, Burkhard Schmitz, Hartwin Lier, Andreas Huge
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-22 (2017)
Scientific Reports
Scientific Reports
We investigated the dynamics of immediate and initial gene expression response to different gravitational environments in human Jurkat T lymphocytic cells and compared expression profiles to identify potential gravity-regulated genes and adaptation p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c4096a0fd48d88aae37761b1516ed92
https://doi.org/10.1038/s41598-017-05580-x
https://doi.org/10.1038/s41598-017-05580-x
Autor:
Swantje Hauschild, Isabell Buttron, Arnold Raem, Hartwin Lier, Cora S. Thiel, Frank Engelmann, Claudia Philpot, Christiane Raig, Felix Unverdorben, Svantje Tauber, Beatrice A. Lauber, Oliver Ullrich, Liliana E. Layer, Katrin Paulsen, Annett Gutewort, Josefine Biskup, Eva Hürlimann
Publikováno v:
BioMed Research International, Vol 2015 (2015)
BioMed Research International
BioMed Research International
Gene expression studies are indispensable for investigation and elucidation of molecular mechanisms. For the process of normalization, reference genes (“housekeeping genes”) are essential to verify gene expression analysis. Thus, it is assumed th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae48f7f2116a40c55367f9bc916b08eb
http://elib.dlr.de/104289/
http://elib.dlr.de/104289/
Autor:
Stephanie Engeli, Andreas Huge, Josefine Biskup, Claudia Dumrese, Felix Unverdorben, Dana Michaela Simmet, Ines Barz, Lisa Mutschler, Eva Hürlimann, Svantje Tauber, Daniel Hofmänner, Frank Engelmann, Oliver Ullrich, Hartwin Lier, Isabell Buttron, Gesine Bradacs, Sonja Krammer, Cora S. Thiel, Liliana E. Layer, Christiane Raig, Nadine Gölz, Katrin Paulsen, Annett Gutewort, Gabriela Rieder, Swantje Hauschild, Claudia Philpot
Publikováno v:
BioMed Research International, Vol 2015 (2015)
BioMed Research International
BioMed Research International
Cells of the immune system are highly sensitive to altered gravity, and the monocyte as well as the macrophage function is proven to be impaired under microgravity conditions. In our study, we investigated the surface expression of ICAM-1 protein and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::677da984e1a2f41ebf65d353f782427a
https://www.zora.uzh.ch/id/eprint/106973/
https://www.zora.uzh.ch/id/eprint/106973/