Zobrazeno 1 - 10
of 81
pro vyhledávání: '"Hartwig Steckel"'
Publikováno v:
Pharmaceutics, Vol 12, Iss 12, p 1154 (2020)
Oseltamivir phosphate (OP) is an antiviral drug available only as oral therapy for the treatment of influenza and as a potential treatment option when in combination with other medication in the fight against the corona virus disease (COVID-19) pneum
Externí odkaz:
https://doaj.org/article/40a5698dddfb40118bfc41a453662d9a
Publikováno v:
Pharmaceutics, Vol 6, Iss 2, Pp 195-219 (2014)
Nasal drug delivery can be assessed by a variety of means and regulatory agencies, e.g., the Food and Drug Administration (FDA) and the European Medicines Agency (EMA) have published a set of guidelines and regulations proposing in vitro test methods
Externí odkaz:
https://doaj.org/article/4b3c4b233b574479ac0b8e50debe40ef
Autor:
Eman S Zarie, Viktor Kaidas, Dawit Gedamu, Yogendra K Mishra, Rainer Adelung, Franz H Furkert, Regina Scherließ, Hartwig Steckel, Birte Groessner-Schreiber
Publikováno v:
PLoS ONE, Vol 7, Iss 8, p e40746 (2012)
Nanostructuring of drug delivery systems offers many promising applications like precise control of dissolution and release kinetics, enhanced activities, flexibility in terms of surface coatings, integration into implants, designing the appropriate
Externí odkaz:
https://doaj.org/article/28d10785a2c14997b253cb1b72880696
Autor:
J. Kamplade, Peter Walzel, P. Fakner, Mathias Mönckedieck, Regina Scherließ, Nora Anne Urbanetz, Hartwig Steckel
Publikováno v:
Drying Technology. 35:1843-1857
This study was dealing with the spray drying of tailored mannitol particles as carriers in dry powder inhalation formulations. A self-constructed spray tower equipped with a laminar rotary ...
Autor:
Hartwig Steckel, Niklas Renner, Nora Anne Urbanetz, Martin Sommerfeld, Sarah Zellnitz, Yan Cui, Regina Scherließ
Publikováno v:
Particles in Contact ISBN: 9783030158989
The design of formulations intended for inhalation is a major challenge since many different factors need consideration in order to guarantee major drug delivery. This becomes especially important in dry powder inhalation. Balanced inter-particle int
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9fff6a19faa6ef6c357dc0b276980482
https://doi.org/10.1007/978-3-030-15899-6_16
https://doi.org/10.1007/978-3-030-15899-6_16
Autor:
Katharina Stank, Tessa Lühmann, Frederic Vollmers, Lorenz Meinel, Hartwig Steckel, Jens-Christoph Rybak, Michael Schmidt, Boris Kardziev, Ronja Wittmann, Isabel Schultz, Petra Högger
Publikováno v:
ACS Biomaterials Science & Engineering. 1:119-129
Insulin-like growth factor I (IGF-I) is a strong anabolic peptide with promising therapeutic value in muscle wasting diseases such as sarcopenia. We report a pulmonary IGF-I delivery system deploying silk-fibroin (SF) as carrier and in comparison to
Autor:
Mats Hertel, Hartwig Steckel, Mirjam Kobler, Regina Scherließ, Sabine Hauptstein, Eugen Schwarz
Publikováno v:
International journal of pharmaceutics. 535(1-2)
Many efforts have been made in the past to understand the function of lactose fines which are given as a ternary component to carrier-based dry powder inhaler formulations. It is undisputed that fines can significantly improve the performance of such
Autor:
Hartwig Steckel, Mirjam Kobler, Sabine Hauptstein, Mats Hertel, Eugen Schwarz, Regina Scherließ
Publikováno v:
International journal of pharmaceutics. 534(1-2)
The blending process is a key step in the production of dry powder inhaler formulations, but only little is known about the influence of process parameters. This is especially true for high shear blending of ternary formulations. For this reason, thi
Autor:
J. Kamplade, Nora Anne Urbanetz, Hartwig Steckel, Mathias Mönckedieck, Peter Walzel, Regina Scherließ, P. Fakner
Publikováno v:
International journal of pharmaceutics. 524(1-2)
Nowadays, dry powder inhalation as applied in the therapy of pulmonary diseases is known as a very effective route of drug delivery to the lungs. Here, the system of coarse carrier and fine drug particles attached to the carrier surface has successfu
Autor:
Rajeev Ahuja, Mirjam Lilja, Hartwig Steckel, Jan Henrik Sörensen, Maria Strømme, Taoran Ma, Baochang Wang
Publikováno v:
Applied Surface Science. 314:376-383
Antibiotic incorporation into hydroxyapatite (HA) coatings by co-precipitation and the impact of bone relevant doping elements on the adsorption kinetics are investigated from both theoretical and experimental points of view. Tobramycin interactions